Transglutaminase 3 suppresses proliferation and cisplatin resistance of cervical cancer cells by inactivation of the PI3K/AKT pathway. | Transglutaminase 3 suppresses proliferation and cisplatin resistance of cervical cancer cells by inactivation of the PI3K/AKT pathway. Chen R, Fang T, Liu N, Shi X, Wang J, Yu H. | 03/14/2024 |
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis. | Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis. Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM., Free PMC Article | 09/7/2023 |
Circular RNA ciRS-7 promotes laryngeal squamous cell carcinoma development by inducing TGM3 hypermethylation via miR-432-5p/DNMT3B axis. | Circular RNA ciRS-7 promotes laryngeal squamous cell carcinoma development by inducing TGM3 hypermethylation via miR-432-5p/DNMT3B axis. Zhao K, Ye F, Gao P, Zhu X, Hao S, Lou W. | 12/10/2022 |
Transglutaminase 3 expression in hepatocellular carcinoma patients: Correlation with tumor features and survival profile. | Transglutaminase 3 expression in hepatocellular carcinoma patients: Correlation with tumor features and survival profile. Wu D, Zhang R, Zhan L. | 07/23/2022 |
T Cell Response Toward Tissue-and Epidermal-Transglutaminases in Coeliac Disease Patients Developing Dermatitis Herpetiformis. | T Cell Response Toward Tissue-and Epidermal-Transglutaminases in Coeliac Disease Patients Developing Dermatitis Herpetiformis. Caproni M, Capone M, Rossi MC, Santarlasci V, Maggi L, Mazzoni A, Rossettini B, Renzi D, Quintarelli L, Bianchi B, Ninci A, Lami G, Calabrò A, Cosmi L, Annunziato F, Liotta F., Free PMC Article | 09/25/2021 |
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection. | TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection. Hu JW, Yang ZF, Li J, Hu B, Luo CB, Zhu K, Dai Z, Cai JB, Zhan H, Hu ZQ, Hu J, Cao Y, Qiu SJ, Zhou J, Fan J, Huang XW. | 07/24/2021 |
Downregulation of miR106b3p increases sensitivity to cisplatin in esophageal cancer cells by targeting TGM3. | Downregulation of miR‑106b‑3p increases sensitivity to cisplatin in esophageal cancer cells by targeting TGM3. Zhu Y, Zhang Y, Li X, Su Y, Wang N, Chen M, Yang Z. | 05/15/2021 |
TGM3 functions as a tumor suppressor by repressing epithelialtomesenchymal transition and the PI3K/AKT signaling pathway in colorectal cancer. | TGM3 functions as a tumor suppressor by repressing epithelial‑to‑mesenchymal transition and the PI3K/AKT signaling pathway in colorectal cancer. Feng Y, Ji D, Huang Y, Ji B, Zhang Y, Li J, Peng W, Zhang C, Zhang D, Sun Y, Xu Z., Free PMC Article | 09/26/2020 |
Transglutaminase 3 Promotes Skin Inflammation in Atopic Dermatitis by Activating Monocyte-Derived Dendritic Cells via DC-SIGN. | Transglutaminase 3 Promotes Skin Inflammation in Atopic Dermatitis by Activating Monocyte-Derived Dendritic Cells via DC-SIGN. Su H, Luo Y, Sun J, Liu X, Ling S, Xu B, Zhang Y, Liu J, Li W, Wang B, Yao X. | 09/19/2020 |
TGM3 played an important role in OL malignant transformation | Transglutaminase 3 contributes to malignant transformation of oral leukoplakia to cancer. Wu X, Wang R, Jiao J, Li S, Yu J, Yin Z, Zhou L, Gong Z. | 05/18/2019 |
aberrant TGase 1 and TGase 3 localization and distribution are closely related to hyper-keratinization in Oral lichen planus. | Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus. Shimada K, Ochiai T, Hasegawa H., Free PMC Article | 01/19/2019 |
Patents having higher level of TGM-3 expression have good response to chemo-radiotherapy and also have better overall survival. TGM-3 may serve as a candidate biomarker for responsiveness to chemo-radiotherapy treatment in oral squamous cell carcinoma patients | Tissue and serum expression of TGM-3 may be prognostic marker in patients of oral squamous cell carcinoma undergoing chemo-radiotherapy. Nayak S, Bhatt MLB, Goel MM, Gupta S, Mahdi AA, Mishra A, Mehrotra D., Free PMC Article | 12/22/2018 |
Cultured duodenal biopsies from patients with dermatitis herpetiformis produce transglutaminase-3 antibodies. | Ex vivo Culture of Duodenal Biopsies from Patients with Dermatitis Herpetiformis Indicates that Transglutaminase 3 Antibody Production Occurs in the Gut. Hietikko M, Hervonen K, Ilus T, Salmi T, Huhtala H, Laurila K, Rauhavirta T, Reunala T, Kaukinen K, Lindfors K. | 09/8/2018 |
Levels of TG3-IgA IC significantly elevated in plasma as well as in serum samples of untreated patients with dermatitis herpetiformis compared with healthy controls. | Circulating Transglutaminase 3-Immunoglobulin A Immune Complexes in Dermatitis Herpetiformis. Görög A, Németh K, Kolev K, Zone JJ, Mayer B, Silló P, Bognár P, Kárpáti S. | 05/26/2018 |
studies demonstrate that TGase-catalyzed transamidation and activation of rac1 and cdc42 results from stimulation of multiple types of receptors and this novel signaling pathway can regulate dendritic spine morphology and plasticity. | Receptor-stimulated transamidation induces activation of Rac1 and Cdc42 and the regulation of dendritic spines. Mi Z, Si T, Kapadia K, Li Q, Muma NA., Free PMC Article | 09/2/2017 |
The two enzymes PADI3 and TGM3, responsible for posttranslational protein modifications, and their target structural protein TCHH are all involved in hair shaft formation. | Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome. Ü Basmanav FB, Cau L, Tafazzoli A, Méchin MC, Wolf S, Romano MT, Valentin F, Wiegmann H, Huchenq A, Kandil R, Garcia Bartels N, Kilic A, George S, Ralser DJ, Bergner S, Ferguson DJP, Oprisoreanu AM, Wehner M, Thiele H, Altmüller J, Nürnberg P, Swan D, Houniet D, Büchner A, Weibel L, Wagner N, Grimalt R, Bygum A, Serre G, Blume-Peytavi U, Sprecher E, Schoch S, Oji V, Hamm H, Farrant P, Simon M, Betz RC., Free PMC Article | 05/27/2017 |
Data indicate a decrease in transglutaminases TG1 and TG3 transcripts by about 70% in foreskins from patients with balanitis xerotica obliterans (BXO) BXO in comparison with patients without BXO and an increase in transglutaminase TG2 mRNA levels by 2.9 fold. | Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. Russo T, Currò M, Barbera A, Caccamo D, Antonuccio P, Arena S, Montalto AS, Parisi S, Marseglia L, Gitto E, Ientile R, Impellizzeri P, Romeo C., Free PMC Article | 04/1/2017 |
Our data collectively demonstrate that TGM3 can be a candidate tumor suppressor that is able to induce esophageal cancer cell proliferation and migration | Transglutaminase 3 protein modulates human esophageal cancer cell growth by targeting the NF-κB signaling pathway. Li W, Zhang Z, Zhao W, Han N. | 03/18/2017 |
mRNA expression of transglutaminase 1 and transglutaminase 3 was significantly decreased in patients with chronic periodontitis compared with a healthy control group. | Differential expression of transglutaminase genes in patients with chronic periodontitis. Currò M, Matarese G, Isola G, Caccamo D, Ventura VP, Cornelius C, Lentini M, Cordasco G, Ientile R. | 05/28/2016 |
Transglutaminase 3 present in the IgA aggregates in dermatitis herpetiformis skin is enzymatically active and binds soluble fibrinogen. | Transglutaminase 3 present in the IgA aggregates in dermatitis herpetiformis skin is enzymatically active and binds soluble fibrinogen. Taylor TB, Schmidt LA, Meyer LJ, Zone JJ. | 03/28/2015 |
New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22(rs7006527). | Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. Stacey SN, Sulem P, Gudbjartsson DF, Jonasdottir A, Thorleifsson G, Gudjonsson SA, Masson G, Gudmundsson J, Sigurgeirsson B, Benediktsdottir KR, Thorisdottir K, Ragnarsson R, Fuentelsaz V, Corredera C, Grasa M, Planelles D, Sanmartin O, Rudnai P, Gurzau E, Koppova K, Hemminki K, Nexø BA, Tjønneland A, Overvad K, Johannsdottir H, Helgadottir HT, Thorsteinsdottir U, Kong A, Vogel U, Kumar R, Nagore E, Mayordomo JI, Rafnar T, Olafsson JH, Stefansson K., Free PMC Article | 01/17/2015 |
IgA-anti-TG1 antibodies were found in 2% and IgA-anti-TG3 antibodies in 3% of patients with active atopic dermatitis (AD). Two out of the 5 patients with AD and concomitant celiac disease had IgA-anti-TG1 and IgA-anti-TG2 antibodies. | Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis. Ress K, Teesalu K, Annus T, Putnik U, Lepik K, Luts K, Uibo O, Uibo R., Free PMC Article | 01/17/2015 |
TGM3, a candidate tumor suppressor, contributes to the carcinogenesis and development of human head and neck cancer. | TGM3, a candidate tumor suppressor gene, contributes to human head and neck cancer. Wu X, Cao W, Wang X, Zhang J, Lv Z, Qin X, Wu Y, Chen W., Free PMC Article | 07/12/2014 |
Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. | Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. Liedén A, Winge MC, Sääf A, Kockum I, Ekelund E, Rodriguez E, Fölster-Holst R, Franke A, Illig T, Tengvall-Linder M, Baurecht H, Weidinger S, Wahlgren CF, Nordenskjöld M, Bradley M., Free PMC Article | 05/18/2013 |
The low expression of TGM3 may contribute to the carcinogenesis and development of laryngeal carcinoma. | [Expression of TGM3 protein and its significance in laryngeal carcinoma]. Liu J, Zhou Y, Wan J, Liu Z. | 08/4/2012 |