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    THBS2 thrombospondin 2 [ Homo sapiens (human) ]

    Gene ID: 7058, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Heterozygous THBS2 pathogenic variant causes Ehlers-Danlos syndrome with prominent vascular features in humans and mice.

    Heterozygous THBS2 pathogenic variant causes Ehlers-Danlos syndrome with prominent vascular features in humans and mice.
    Hadar N, Porgador O, Cohen I, Levi H, Dolgin V, Yogev Y, Sued-Hendrickson S, Shelef I, Didkovsky E, Eskin-Schwartz M, Birk OS., Free PMC Article

    05/3/2024
    THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

    THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.
    Corbella E, Fara C, Covarelli F, Porreca V, Palmisano B, Mignogna G, Corsi A, Riminucci M, Maras B, Mancone C., Free PMC Article

    02/15/2024
    Thrombospondin 2 is a key determinant of fibrogenesis in non-alcoholic fatty liver disease.

    Thrombospondin 2 is a key determinant of fibrogenesis in non-alcoholic fatty liver disease.
    Kimura T, Iwadare T, Wakabayashi SI, Kuldeep S, Nakajima T, Yamazaki T, Aomura D, Zafar H, Iwaya M, Joshita S, Uehara T, Pydi SP, Tanaka N, Umemura T.

    01/31/2024
    Thrombospondin 2 is a novel biomarker of essential hypertension and associated with nocturnal Na[+] excretion and insulin resistance.

    Thrombospondin 2 is a novel biomarker of essential hypertension and associated with nocturnal Na(+) excretion and insulin resistance.
    Zhou X, Zhang L, Lin X, Chen X, Liu H, Yuan X, Zhao Q, Wang W, Lei X, Jose PA, Deng C, Yang J.

    11/15/2023
    Serum THBS2 is a potential biomarker for the diagnosis of non-small cell lung cancer.

    Serum THBS2 is a potential biomarker for the diagnosis of non-small cell lung cancer.
    Xiong L, Zhu C, Lu Y, Chen M, Li M.

    11/6/2023
    MiR-214-3p suppresses cervical cancer cell metastasis by downregulating THBS2.

    MiR-214-3p suppresses cervical cancer cell metastasis by downregulating THBS2.
    Wang X, Xu J, Hua F, Wang Y, Fang G, Zhang H, Wu X.

    11/6/2023
    Hsa_circ_0015382 is involved in the pathogenesis of preeclampsia by mediating THBS2 expression.

    Hsa_circ_0015382 is involved in the pathogenesis of preeclampsia by mediating THBS2 expression.
    Wang Y, Liu L, Wang J, Gao Y.

    08/31/2023
    Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.

    Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.
    Fang K, Deng Y, Yang P, Zhang Y, Luo D, Wang F, Cai Z, Liu Y.

    05/24/2023
    CEBPB regulates the migration, invasion and EMT of breast cancer cells by inhibiting THBS2 expression and O-fucosylation.

    CEBPB regulates the migration, invasion and EMT of breast cancer cells by inhibiting THBS2 expression and O-fucosylation.
    Qi L, Sun B, Yang B, Lu S.

    05/22/2023
    COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.

    COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.
    Li H, Cao L, Li H., Free PMC Article

    04/14/2023
    Identification of BGN and THBS2 as metastasis-specific biomarkers and poor survival key regulators in human colon cancer by integrated analysis.

    Identification of BGN and THBS2 as metastasis-specific biomarkers and poor survival key regulators in human colon cancer by integrated analysis.
    He Z, Lin J, Chen C, Chen Y, Yang S, Cai X, He Y, Liu S., Free PMC Article

    11/26/2022
    Prospective associations of circulating thrombospondin-2 level with heart failure hospitalization, left ventricular remodeling and diastolic function in type 2 diabetes.

    Prospective associations of circulating thrombospondin-2 level with heart failure hospitalization, left ventricular remodeling and diastolic function in type 2 diabetes.
    Lee CH, Wu MZ, Lui D, Fong C, Ren QW, Yu SY, Yuen M, Chow WS, Huang JY, Xu A, Yiu KH, Lam K., Free PMC Article

    11/12/2022
    Tsp2 Facilitates Tumor-associated Fibroblasts Formation and Promotes Tumor Progression in Retroperitoneal Liposarcoma.

    Tsp2 Facilitates Tumor-associated Fibroblasts Formation and Promotes Tumor Progression in Retroperitoneal Liposarcoma.
    Xu C, Yan L, Guan X, Wang Z, Wu J, Lv A, Liu D, Liu F, Dong B, Zhao M, Jia L, Tian X, Hao C., Free PMC Article

    08/27/2022
    Circ-OPHN1 suppresses the proliferation, migration, and invasion of trophoblast cells through mediating miR-558/THBS2 axis.

    Circ-OPHN1 suppresses the proliferation, migration, and invasion of trophoblast cells through mediating miR-558/THBS2 axis.
    Li Y, Chen J, Song S.

    07/2/2022
    THBS2 promotes cell migration and invasion in colorectal cancer via modulating Wnt/beta-catenin signaling pathway.

    THBS2 promotes cell migration and invasion in colorectal cancer via modulating Wnt/β-catenin signaling pathway.
    Qu HL, Hasen GW, Hou YY, Zhang CX.

    05/7/2022
    Circ_0007580 knockdown strengthens the radiosensitivity of non-small cell lung cancer via the miR-598-dependent regulation of THBS2.

    Circ_0007580 knockdown strengthens the radiosensitivity of non-small cell lung cancer via the miR-598-dependent regulation of THBS2.
    Yang Z, Wu H, Zhang K, Rao S, Qi S, Liu M, Chen Y, Wang Y., Free PMC Article

    03/26/2022
    mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

    mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.
    Auguściak-Duma A, Lesiak M, Stępień K, Gutmajster E, Sieroń AL.

    03/19/2022
    THBS2/CA19-9 Detecting Pancreatic Ductal Adenocarcinoma at Diagnosis Underperforms in Prediagnostic Detection: Implications for Biomarker Advancement.

    THBS2/CA19-9 Detecting Pancreatic Ductal Adenocarcinoma at Diagnosis Underperforms in Prediagnostic Detection: Implications for Biomarker Advancement.
    Udgata S, Takenaka N, Bamlet WR, Oberg AL, Yee SS, Carpenter EL, Herman D, Kim J, Petersen GM, Zaret KS., Free PMC Article

    02/12/2022
    MicroRNA 1228 Mediates the Viability of High Glucose-Cultured Renal Tubule Cells through Targeting Thrombospondin 2 and PI3K/AKT Signaling Pathway.

    MicroRNA 1228 Mediates the Viability of High Glucose-Cultured Renal Tubule Cells through Targeting Thrombospondin 2 and PI3K/AKT Signaling Pathway.
    Mo T, Fu Q, Hu X, Fu Y, Li J.

    02/5/2022
    Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis.

    Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis.
    Kozumi K, Kodama T, Murai H, Sakane S, Govaere O, Cockell S, Motooka D, Kakita N, Yamada Y, Kondo Y, Tahata Y, Yamada R, Hikita H, Sakamori R, Kamada Y, Daly AK, Anstee QM, Tatsumi T, Morii E, Takehara T., Free PMC Article

    01/15/2022
    Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer.

    Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer.
    Wang Y, Zheng K, Chen X, Chen R, Zou Y., Free PMC Article

    12/18/2021
    Correlation analysis between TSP2, MMP-9 and perihematoma edema, as well as the short-term prognosis of patients with hypertensive intracerebral hemorrhage.

    Correlation analysis between TSP2, MMP-9 and perihematoma edema, as well as the short-term prognosis of patients with hypertensive intracerebral hemorrhage.
    Cao D, Liu F, Liu Q, Feng J.

    12/11/2021
    miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis.

    miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis.
    Hsu CH, Liu IF, Kuo HF, Li CY, Lian WS, Chang CY, Chen YH, Liu WL, Lu CY, Liu YR, Lin TC, Lee TY, Huang CY, Hsieh CC, Liu PL., Free PMC Article

    11/6/2021
    Circulating Thrombospondin-2 as a Novel Fibrosis Biomarker of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes.

    Circulating Thrombospondin-2 as a Novel Fibrosis Biomarker of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes.
    Lee CH, Seto WK, Lui DT, Fong CH, Wan HY, Cheung CY, Chow WS, Woo YC, Yuen MF, Xu A, Lam KS.

    10/23/2021
    Prognostic and Immunological Role of THBS2 in Colorectal cancer.

    Prognostic and Immunological Role of THBS2 in Colorectal cancer.
    Deng B, Liu XP, Wang X., Free PMC Article

    10/16/2021
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