| Thyroid hormone Beta receptor agonists for treatment of kidney disease: A promising agent? | Thyroid hormone Beta receptor agonists for treatment of kidney disease: A promising agent?
Copur S, Yavuz F, Kanbay M. | 10/23/2023 |
| Effect of the Fetal THRB Genotype on the Placenta. | Effect of the Fetal THRB Genotype on the Placenta.
Salas-Lucia F, Stan MN, James H, Rajwani A, Liao XH, Dumitrescu AM, Refetoff S., Free PMC Article | 09/20/2023 |
| Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor beta Gene Mutation. | Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor β Gene Mutation.
Lai HP, Chen MH., Free PMC Article | 03/3/2023 |
| Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome. | Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome.
Cui B, Xiao X, Wang J, Wang H, Wu C, Yan Y, Zheng J, Wang J, Zong Y, Zhang Y, Hui R, Gerdes AM, Wang Y. | 01/15/2022 |
| Life Without Thyroid Hormone Receptor. | Life Without Thyroid Hormone Receptor.
Shi YB., Free PMC Article | 10/23/2021 |
| Structural insights revealed by two novel THRB mutations. | Structural insights revealed by two novel THRB mutations.
Cardoso LF, de Carvalho Melo MC, Takahashi MH, Nascimento AS, Chiamolera MI, Maciel LMZ. | 07/10/2021 |
| Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene. | Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene.
Pajek M, Avbelj Stefanija M, Trebusak Podkrajsek K, Suput Omladic J, Zerjav Tansek M, Battelino T, Groselj U., Free PMC Article | 06/19/2021 |
| Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival. | Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival.
Piqué DG, Greally JM, Mar JC., Free PMC Article | 04/24/2021 |
| Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study. | Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study.
Uter J, Heldmann M, Rogge B, Obst M, Steinhardt J, Brabant G, Moran C, Chatterjee K, Münte TF., Free PMC Article | 04/24/2021 |
| Characterization of adipogenic, PPARgamma, and TRbeta activities in house dust extracts and their associations with organic contaminants. | Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants.
Kassotis CD, Hoffman K, Phillips AL, Zhang S, Cooper EM, Webster TF, Stapleton HM., Free PMC Article | 01/16/2021 |
| Thyroid Hormone Facilitates in vitro Decidualization of Human Endometrial Stromal Cells via Thyroid Hormone Receptors. | Thyroid Hormone Facilitates in vitro Decidualization of Human Endometrial Stromal Cells via Thyroid Hormone Receptors.
Kakita-Kobayashi M, Murata H, Nishigaki A, Hashimoto Y, Komiya S, Tsubokura H, Kido T, Kida N, Tsuzuki-Nakao T, Matsuo Y, Bono H, Hirota K, Okada H. | 01/16/2021 |
| Thyroid hormone resistance syndrome with P453T mutation in thyroid hormone receptor beta gene: A pedigree report. | Thyroid hormone resistance syndrome with P453T mutation in thyroid hormone receptor β gene: A pedigree report.
Yusufu A, Chen WJ, Zhang MC., Free PMC Article | 11/21/2020 |
| Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor beta1 Are Inversely Associated with Survival in Primary Breast Cancer. | Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor β1 Are Inversely Associated with Survival in Primary Breast Cancer.
Shao W, Kuhn C, Mayr D, Ditsch N, Kailuweit M, Wolf V, Harbeck N, Mahner S, Jeschke U, Cavaillès V, Sixou S., Free PMC Article | 09/12/2020 |
| wild-type intranuclear dynamics of acetylation mimic and sumoylation-deficient TRs, whereas the nonacetylation mimic had significantly reduced mobility and transcriptional activity. | Acetylation modulates thyroid hormone receptor intracellular localization and intranuclear mobility.
Anyetei-Anum CS, Evans RM, Back AM, Roggero VR, Allison LA., Free PMC Article | 06/6/2020 |
| Identification of a novel mutation in the thyroid hormone receptor beta gene that causes thyroid hormone resistance syndrome. | Identification of a novel mutation in the thyroid hormone receptor β gene that causes thyroid hormone resistance syndrome: A case report.
Wang J, Lv H., Free PMC Article | 04/4/2020 |
| analysis of a novel mutation in the THRB gene (c.1069 G>C, p.G357R)with a role in the resistance to thyroid hormone beta syndrome | A Novel Thyroid Hormone Receptor Beta Mutation (G357R) in a Family with Resistance to Thyroid Hormone Beta: Extending the Borders of the "Hot" Region in the THRB Gene.
Censi S, Barollo S, Watutantrige-Fernando S, Manso J, Ferrara AM, Mian C. | 02/29/2020 |
| Mutation in the THRB gene is associated with Thyroid hormone resistance syndrome. | Thyroid hormone resistance from newborns to adults: a Spanish experience.
Vela A, Pérez-Nanclares G, Ríos I, Rica I, Portillo N, Castaño L, Spanish Group for the Study of RTH. | 12/28/2019 |
| A patient with thyroid hormone resistance syndrome was discribed. A heterozygous mutation c.728G>A in TRbeta gene was found. | Resistance to thyroid hormone with a mutation of the thyroid β receptor gene in an eight-month-old infant - a case report.
Foryś-Dworniczak EA, Moran C, Kalina-Faska B, Małecka-Tendera E, Zachurzok A. | 07/13/2019 |
| Age-related decrease of THRB expression in peripheral blood mononuclear cells of elderly and long-lived humans might be, in part, a result of the increased methylation of its promoter, but is unrelated to the activity of the miRNAs | Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.
Pawlik-Pachucka E, Budzinska M, Wicik Z, Domaszewska-Szostek A, Owczarz M, Roszkowska-Gancarz M, Gewartowska M, Puzianowska-Kuznicka M. | 02/23/2019 |
| These results demonstrate that thyroid hormone down-regulated basal NR4A1 mRNA levels in the pituitary, and the direct binding of thyroid hormone receptor was not required. | Pituitary NR4A1 is negatively regulated by thyroid hormone without direct binding of thyroid hormone receptors on the gene.
Okamura T, Nakajima Y, Shibusawa N, Horiguchi K, Matsumoto S, Yamada E, Tomaru T, Ishii S, Ozawa A, Ishizuka T, Hashimoto K, Okada S, Satoh T, Yamada M. | 02/16/2019 |
| transactivation of the PDZK1-promoter by triiodothyronine mediated by thyroid hormone receptors (THR) alpha and beta. | PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ.
Ferreira C, Prestin K, Hussner J, Zimmermann U, Meyer Zu Schwabedissen HE. | 02/16/2019 |
| Mechanism of TRbeta repression of oncogenic gene expression: TRbeta recruitment of BRG1 induces chromatin compaction and diminishes RUNX2 expression. Therefore, BRG1-mediated chromatin remodeling may be obligatory for TRbeta transcriptional repression and tumor suppressor function in thyroid tumorigenesis. | Thyroid Hormone Receptor β Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling.
Gillis NE, Taber TH, Bolf EL, Beaudet CM, Tomczak JA, White JH, Stein JL, Stein GS, Lian JB, Frietze S, Carr FE., Free PMC Article | 02/9/2019 |
| These data indicate that m-TRbeta1 can act as a tumor suppressor in hepatocarcinoma and its role was significantly better than that of TRbeta1. | Overexpression of modified human TRβ1 suppresses the growth of hepatocarcinoma SK-hep1 cells in vitro and in xenograft models.
Peng X, Zhou Y, Sun Y, Song W, Meng X, Zhao C, Zhao R., Free PMC Article | 12/22/2018 |
| Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. | Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.
Gao X, Lee HY, Li W, Platt RJ, Barrasa MI, Ma Q, Elmes RR, Rosenfeld MG, Lodish HF., Free PMC Article | 06/9/2018 |
| Report of a novel mutation T273R in the THRB gene of patients exhibiting signs of the syndrome of resistance to thyroid hormone. Authors propose that the trans-activating function of TRbeta is likely dominantly hindered in these patients. | Novel Mutation (T273R) in Thyroid Hormone Receptor β Gene Provides Further Insight into Cryptic Negative Regulation by Thyroid Hormone.
Kaššák F, Hána V, Saudek V, Kostrouchová M. | 05/5/2018 |