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    TNF tumor necrosis factor [ Homo sapiens (human) ]

    Gene ID: 7124, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Relationship of TNFalpha-238 G/A (rs 361525) genotypes with TNFalpha gene expression in liver and pancreas disorders in sample of beta thalassemia major adult Iraqi patients.

    Relationship of TNFα-238 G/A (rs 361525) genotypes with TNFα gene expression in liver and pancreas disorders in sample of beta thalassemia major adult Iraqi patients.
    Luaibi HA, Mohammed BJ.

    10/31/2024
    Human microglia-derived proinflammatory cytokines facilitate human retinal ganglion cell development and regeneration.

    Human microglia-derived proinflammatory cytokines facilitate human retinal ganglion cell development and regeneration.
    Subramani M, Lambrecht B, Ahmad I., Free PMC Article

    10/16/2024
    TNF-alpha and RPLP0 drive the apoptosis of endothelial cells and increase susceptibility to high-altitude pulmonary edema.

    TNF-α and RPLP0 drive the apoptosis of endothelial cells and increase susceptibility to high-altitude pulmonary edema.
    Ge YL, Li PJ, Bu YR, Zhang B, Xu J, He SY, Cao QL, Bai YG, Ma J, Zhang L, Zhou J, Xie MJ., Free PMC Article

    09/23/2024
    Identification of TNF-alpha as Major Susceptible Risk Locus for Vitiligo: A Systematic Review and Meta-Analysis Study in the Asian Population.

    Identification of TNF-α as Major Susceptible Risk Locus for Vitiligo: A Systematic Review and Meta-Analysis Study in the Asian Population.
    Dutta T, Sengupta S, Adhya S, Saha A, Sengupta D, Mondal R, Naskar S, Bhattacharjee S, Sengupta M.

    09/1/2024
    TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype.

    TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype.
    Hayderi A, Zegeye MM, Meydan S, Sirsjö A, Kumawat AK, Ljungberg LU., Free PMC Article

    08/31/2024
    Cervical cancer risk in association with TNF-alpha gene polymorphisms in Bangladeshi women.

    Cervical cancer risk in association with TNF-alpha gene polymorphisms in Bangladeshi women.
    Tishe ZH, Shawkat S, Popy MN, Mumu SB, Ferdous A, Raisa MJ, Hasan M, Sultana TN, Chaity NI, Apu MNH, Mostaid MS.

    08/20/2024
    The role of TNF-alpha and il-6 SNP in polycystic ovary syndrome susceptibility.

    The role of TNF-α and il-6 SNP in polycystic ovary syndrome susceptibility.
    Raheem BM, Obaid RM, Ali BR, Al-Fahham AA.

    08/4/2024
    Effects of tumor necrosis factor-alpha rs1800629 and interleukin-10 rs1800872 genetic variants on type 2 diabetes mellitus susceptibility and metabolic parameters among Jordanians.

    Effects of tumor necrosis factor-α rs1800629 and interleukin-10 rs1800872 genetic variants on type 2 diabetes mellitus susceptibility and metabolic parameters among Jordanians.
    Mousa LN, Jarrar Y, Gharaibeh M, Alhawari H.

    07/31/2024
    Short communication: TNF-alpha and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10.

    Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10.
    Jiang W, Block ME, Boosani CS., Free PMC Article

    07/29/2024
    Effects of SNPs on TNF-alpha and IL-10 cytokine expression in TB and HIV patients in the Capricorn district, Limpopo Province, South Africa.

    Effects of SNPs on TNF-α and IL-10 cytokine expression in TB and HIV patients in the Capricorn district, Limpopo Province, South Africa.
    Manabile MA, Maguga-Phasha TC, Makgatho ME., Free PMC Article

    07/26/2024
    SorLA restricts TNFalpha release from microglia to shape a glioma-supportive brain microenvironment.

    SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.
    Kaminska P, Ovesen PL, Jakiel M, Obrebski T, Schmidt V, Draminski M, Bilska AG, Bieniek M, Anink J, Paterczyk B, Jensen AMG, Piatek S, Andersen OM, Aronica E, Willnow TE, Kaminska B, Dabrowski MJ, Malik AR., Free PMC Article

    07/16/2024
    TNF-alpha can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone-invasive pituitary adenoma.

    TNF-α can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone-invasive pituitary adenoma.
    Wu X, Gong L, Li B, Bai J, Li C, Zhang Y, Zhu H., Free PMC Article

    06/27/2024
    Association of polymorphisms in the TNFA, TNFRSF1A and TNFRSF1B genes with lepromatous leprosy in Western Mexican patients.

    Association of polymorphisms in the TNFA, TNFRSF1A and TNFRSF1B genes with lepromatous leprosy in Western Mexican patients.
    Montoya-Buelna M, Alvarado-Navarro A, Muñoz-Valle JF, Lopez-Roa RI, Guerrero-Velazquez C, Fafutis-Morris M.

    06/25/2024
    Investigation of the linkage between TNF-alfa rs1800629 polymorphism and preeclampsia risk: A meta-analysis.

    Investigation of the linkage between TNF-alfa rs1800629 polymorphism and preeclampsia risk: A meta-analysis.
    Shafiul Hossen M, Abdul Aziz M, Abdul Barek M, Safiqul Islam M.

    06/24/2024
    Indirect influence of microRNA-146a on the association of IL-6 and TNF-alpha genetic polymorphisms with the increased risk of hip osteoarthritis.

    Indirect influence of microRNA-146a on the association of IL-6 and TNF-α genetic polymorphisms with the increased risk of hip osteoarthritis.
    Tudor K, Baranasic J, Knezevic J, Serer Vicevic M, Sutic M, Dembic Z, Jotanovic Z.

    06/14/2024
    Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-alpha in rheumatoid arthritis.

    Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-α in rheumatoid arthritis.
    Hu F, Shi L, Liu X, Chen Y, Zhang X, Jia Y, Liu X, Guo J, Zhu H, Liu H, Xu L, Li Y, Wang P, Fang X, Xue J, Xie Y, Wei C, Song J, Zheng X, Liu YY, Li Y, Ren L, Xu D, Lu L, Qiu X, Mu R, He J, Wang M, Zhang X, Liu W, Li Z.

    04/25/2024
    BRG1 mediates epigenetic regulation of TNFalpha-induced CCL2 expression in oral tongue squamous cell carcinoma cells.

    BRG1 mediates epigenetic regulation of TNFα-induced CCL2 expression in oral tongue squamous cell carcinoma cells.
    Xu M, Lu X, Zhu F, Sun X, Yao H, Zhang J, Chen W, Zhu H, Liu F, Shi SL, Deng X.

    04/17/2024
    The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity.

    The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity.
    Purnama CA, Meiliana A, Barliana MI, Lestari K, Wijaya A., Free PMC Article

    04/3/2024
    TNF-alpha promotes osteocyte necroptosis by upregulating TLR4 in postmenopausal osteoporosis.

    TNF-α promotes osteocyte necroptosis by upregulating TLR4 in postmenopausal osteoporosis.
    Cui H, Li J, Li X, Su T, Wen P, Wang C, Deng X, Fu Y, Zhao W, Li C, Hua P, Zhu Y, Wan W.

    04/2/2024
    Hepatic expression of tumor necrosis factor-alpha and evaluation of MAPK-p38 and NFkappaB signaling pathways in autoimmune hepatitis.

    Hepatic expression of tumor necrosis factor-α and evaluation of MAPK-p38 and NFκB signaling pathways in autoimmune hepatitis.
    Maria Medeiros de Ataides Bezerra M, Cristina de Farias Andrade I, Cesar Dias de Melo Silva J, Clara Santos Costa A, Ricardo Costa da Silva R, Richardison Silva Vasconcelos L, de Fátima Cavalcanti Toscano Barreto M, Maria Moreira Beltrão Pereira L, Wanessa Santos Rocha S.

    03/29/2024
    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-gamma and TNF-alpha expression and its impact on disease severity.

    Effect of SARS-CoV-2 and Toxoplasma gondii co-infection on IFN-γ and TNF-α expression and its impact on disease severity.
    Abdeltawab MSA, Fateen M, Saad El-Din S, Elmessiery RM, Mohammady Mohamed O, Marzouk Sadek K, Medhat E, Hamed AMR.

    03/29/2024
    TNFalpha-308G>A Polymorphism and Susceptibility to Immune Thrombocytopenia Purpura (ITP): Evidence From a Systematic Review and Meta-analysis.

    TNFα-308G>A Polymorphism and Susceptibility to Immune Thrombocytopenia Purpura (ITP): Evidence From a Systematic Review and Meta-analysis.
    Shams SF, Mehrad-Majd H.

    03/29/2024
    Role of NF-kappaB p65/TNF-alpha in Cell Apoptosis in the Fetal Membranes of Pregnant Women with Preterm Premature Rupture of Membranes.

    Role of NF-κB p65/TNF-α in Cell Apoptosis in the Fetal Membranes of Pregnant Women with Preterm Premature Rupture of Membranes.
    Tang SH, Tang X, Liu L, Peng L, Zhang HM, Zhang H, Long T, Wu PL, Zhang XP.

    03/28/2024
    IL-6, IL-10 and TNF-alpha gene polymorphisms in preeclampsia: a case-control study in a Mexican population.

    IL-6, IL-10 and TNF-α gene polymorphisms in preeclampsia: a case-control study in a Mexican population.
    Mora Palazuelos CE, Aguilar Medina EM, Avendaño Felix MM, Payán RR, Cortez MB, Lara Avila L, Herrera Salazar A, Murillo Llanes J, Sanchez-Schmitz G, Romero Quintana JG.

    03/21/2024
    Association of the TNF-alpha-308G>A gene polymorphism with left ventricular geometry and functional abnormalities in obstructive sleep apnea subjects.

    Association of the TNF-α-308G>A gene polymorphism with left ventricular geometry and functional abnormalities in obstructive sleep apnea subjects.
    Chen S, Wang J, Shui W, Xing X, Zhang Z, Hou R.

    03/20/2024
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