KLF7 enhances the invasion and migration of colorectal cancer cells via the miR-139-5p/TPD52 axis. | KLF7 enhances the invasion and migration of colorectal cancer cells via the miR-139-5p/TPD52 axis. Zhang J, Li Z, Han J, Tian Z, Meng Q, Niu W., Free PMC Article | 08/16/2024 |
Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR. | Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR. Li Y, Zhu X, Zhang C, Yin Y, Chen L, Liu Y, He A, Xia F. | 12/20/2023 |
Cross talk of tumor protein D52 (TPD52) with KLF9, PKCepsilon, and MicroRNA 223 in ovarian cancer. | Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer. Khan K, Zafar S, Badshah Y, Ashraf NM, Rafiq M, Danish L, Shabbir M, Trembley JH, Afsar T, Almajwal A, Razak S., Free PMC Article | 11/7/2023 |
Androgen receptor suppresses lung cancer invasion and increases cisplatin response via decreasing TPD52 expression. | Androgen receptor suppresses lung cancer invasion and increases cisplatin response via decreasing TPD52 expression. Liu S, Hu C, Li M, Zhou W, Wang R, Xiao Y., Free PMC Article | 08/16/2023 |
Tumor protein D52 (TPD52) affects cancer cell metabolism by negatively regulating AMPK. | Tumor protein D52 (TPD52) affects cancer cell metabolism by negatively regulating AMPK. Chen Y, Peng C, Tan W, Yu J, Zayas J, Peng Y, Lou Z, Pei H, Wang L., Free PMC Article | 01/28/2023 |
Circ_0060551 promotes the migration and invasion of cervical cancer by upregulating TPD52. | Circ_0060551 promotes the migration and invasion of cervical cancer by upregulating TPD52. Shi Q, Ma Y, Zhang X, Yin C. | 09/10/2022 |
ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. | ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. Fan Y, Hou T, Dan W, Zhu Y, Liu B, Wei Y, Wang Z, Gao Y, Zeng J, Li L., Free PMC Article | 08/13/2022 |
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer. | Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer. Fan Y, Hou T, Gao Y, Dan W, Liu T, Liu B, Chen Y, Xie H, Yang Z, Chen J, Zeng J, Li L., Free PMC Article | 04/16/2022 |
Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers. | Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers. Shabbir M, Mukhtar H, Syed D, Razak S, Afsar T, Almajwal A, Badshah Y, Aldisi D., Free PMC Article | 11/13/2021 |
Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis. | Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis. Zhang H, Li M, Zhang J, Shen Y, Gui Q., Free PMC Article | 11/6/2021 |
miR-103a-3p Suppresses Cell Proliferation and Invasion by Targeting Tumor Protein D52 in Prostate Cancer. | miR-103a-3p Suppresses Cell Proliferation and Invasion by Targeting Tumor Protein D52 in Prostate Cancer. Ge J, Mao L, Xu W, Fang W, Wang N, Ye D, Dong Z, Guan H, Guan C. | 09/25/2021 |
MicroRNA103a3p promotes metastasis by targeting TPD52 in salivary adenoid cystic carcinoma. | MicroRNA‑103a‑3p promotes metastasis by targeting TPD52 in salivary adenoid cystic carcinoma. Fu M, Chen CW, Yang LQ, Yang WW, Du ZH, Li YR, Li SL, Ge XY. | 05/8/2021 |
LINC01133 contribute to epithelial ovarian cancer metastasis by regulating miR-495-3p/TPD52 axis. | LINC01133 contribute to epithelial ovarian cancer metastasis by regulating miR-495-3p/TPD52 axis. Liu S, Xi X. | 03/28/2021 |
MicroRNA-1323 downregulation promotes migration and invasion of breast cancer cells by targeting tumour protein D52. | MicroRNA-1323 downregulation promotes migration and invasion of breast cancer cells by targeting tumour protein D52. Xu Y, Liu M. | 02/2/2021 |
Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway. | Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway. Wang Z, Li Y, Fan L, Zhao Q, Tan B, Liu R, Li F. | 08/22/2020 |
The Kaplan-Meier curve revealed that TPD52 overexpression was associated with a poor prognosis for patients with AML with good discrimination ( P = 0.013, P = 0.005, and P = 0.032 for the TGCA, GSE12417, and GSE12417, respectively). | Prognostic role of TPD52 in acute myeloid leukemia: A retrospective multicohort analysis. Ha M, Han ME, Kim JY, Jeong DC, Oh SO, Kim YH. | 06/20/2020 |
The expression levels of TPD52 and DNAJB1 were elevated in cholangiocarcinoma (CCA) cell lines, tissues and bile samples, suggesting that these proteins may contribute to tumor pathogenesis. In addition, the expression levels of TPD52 and DNAJB1 were found to be closely associated with the clinical parameters and prognosis of patients with CCA. | Identification of TPD52 and DNAJB1 as two novel bile biomarkers for cholangiocarcinoma by iTRAQ‑based quantitative proteomics analysis. Ren H, Luo M, Chen J, Zhou Y, Li X, Zhan Y, Shen D, Chen B., Free PMC Article | 04/11/2020 |
study suggests that miR-449b-5p, as a novel tumour-suppressive miRNA against nasopharyngeal carcinoma, inhibits proliferation, migration and invasion of nasopharyngeal carcinoma cells via inhibiting TPD52 expression | MicroRNA-449b-5p suppresses cell proliferation, migration and invasion by targeting TPD52 in nasopharyngeal carcinoma. Yin W, Shi L, Mao Y. | 11/30/2019 |
results show a novel interaction partner of TPD52 providing new insights of its functions and ascertain the role of TPD52-PRDX1 interaction in prostate cancer progression. | Tumor protein D52 (isoform 3) interacts with and promotes peroxidase activity of Peroxiredoxin 1 in prostate cancer cells implicated in cell growth and migration. Dasari C, Reddy KRK, Natani S, Murthy TRL, Bhukya S, Ummanni R. | 11/30/2019 |
upregulation of FTH1P3 may promote glioma cell proliferation and inhibit apoptosis via regulation of the miR-224-5p/TPD52 axis. FTH1P3 may provide a novel perspective on the pathogenesis of glioma. | Long non‑coding RNA ferritin heavy polypeptide 1 pseudogene 3 controls glioma cell proliferation and apoptosis via regulation of the microRNA‑224‑5p/tumor protein D52 axis. Zhang Y, Li Y, Wang J, Lei P., Free PMC Article | 02/2/2019 |
MiR-15a-3p enhanced radiosensitivity in cervical cancer by targeting tumor protein D52. | Over-expression of miR-15a-3p enhances the radiosensitivity of cervical cancer by targeting tumor protein D52. Wu Y, Huang J, Xu H, Gong Z. | 11/3/2018 |
Our studies suggested that miR-449a decreased in malignant process of PCa and was accompanied by excess expression of PrLZ. The loss of miR-449a caused PrLZ overexpression regulated prostate cancer progression and metastasis via regulating the stemness features of prostate cancer cells. | Loss of miR-449a-caused PrLZ overexpression promotes prostate cancer metastasis. Chen W, Liu Y, Chen H, Ning H, Ding K., Free PMC Article | 05/26/2018 |
PC-1/PrLZ is a novel candidate involved in DNA double strand break repair and radioresistance, and targeting PC-1/PrLZ may offer promise for an effective method for enhancing the efficiency of radiation therapy for prostate cancer. | Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death. Shang ZF, Wei Q, Yu L, Huang F, Xiao BB, Wang H, Song M, Wang L, Zhou J, Wang J, Li S., Free PMC Article | 02/10/2018 |
data reveal that TPD52 act through activation of JAK/STAT signaling pathway to undertake NB cells differentiation induced by All-Trans-Retinoic Acid. | All-Trans-Retinoic Acid Stimulates Overexpression of Tumor Protein D52 (TPD52, Isoform 3) and Neuronal Differentiation of IMR-32 Cells. Kotapalli SS, Dasari C, Duscharla D, Kami Reddy KR, Kasula M, Ummanni R. | 01/6/2018 |
the present study demonstrated that TPD52 inhibited growth and metastasis of RCC, at least in part, by suppressing the PI3K/Akt signaling pathway. | Tumor Protein D52 (TPD52) Inhibits Growth and Metastasis in Renal Cell Carcinoma Cells Through the PI3K/Akt Signaling Pathway. Zhao Z, Liu H, Hou J, Li T, Du X, Zhao X, Xu W, Xu W, Chang J., Free PMC Article | 11/4/2017 |