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    TRAF3 TNF receptor associated factor 3 [ Homo sapiens (human) ]

    Gene ID: 7187, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TRAF3 loss-of-function reveals the noncanonical NF-kappaB pathway as a therapeutic target in diffuse large B cell lymphoma.

    TRAF3 loss-of-function reveals the noncanonical NF-κB pathway as a therapeutic target in diffuse large B cell lymphoma.
    Li MY, Chong LC, Duns G, Lytle A, Woolcock B, Jiang A, Telenius A, Ben-Neriah S, Nawaz W, Slack GW, Elisia I, Viganò E, Aoki T, Healy S, Krystal G, Venturutti L, Scott DW, Steidl C., Free PMC Article

    05/5/2024
    FOSL1 regulates hyperproliferation and NLRP3-mediated inflammation of psoriatic keratinocytes through the NF-kB signaling via transcriptionally activating TRAF3.

    FOSL1 regulates hyperproliferation and NLRP3-mediated inflammation of psoriatic keratinocytes through the NF-kB signaling via transcriptionally activating TRAF3.
    Liang Y, Han D, Zhang S, Sun L.

    04/25/2024
    The Interaction of OTUB1 and TRAF3 Mediates NLRP3 Inflammasome Activity to Regulate TGF-beta1-induced BEAS-2B Cell Injury.

    The Interaction of OTUB1 and TRAF3 Mediates NLRP3 Inflammasome Activity to Regulate TGF-β1-induced BEAS-2B Cell Injury.
    Shang L, Du Y, Zhao Y, Zhang Y, Liu C.

    11/15/2023
    Effects of TRAF3 on the proliferation and migration of lung adenocarcinoma depend partly on pyroptosis.

    Effects of TRAF3 on the proliferation and migration of lung adenocarcinoma depend partly on pyroptosis.
    Wang W, Wang S, Wang M, Ma Y, Hu W, Wu B, Li C, Zhang D., Free PMC Article

    11/1/2023
    TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responses.

    TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responses.
    Li Y, Zhu L, Ko CJ, Yang JY, Wang H, Manyam G, Wang J, Cheng X, Zhao S, Jie Z., Free PMC Article

    10/28/2023
    Circular RNA SMARCA5 inhibits cholangiocarcinoma via microRNA-95-3p/tumor necrosis factor receptor associated factor 3 axis.

    Circular RNA SMARCA5 inhibits cholangiocarcinoma via microRNA-95-3p/tumor necrosis factor receptor associated factor 3 axis.
    Wang G, Gao X, Sun Z, He T, Huang C, Li S, Long H., Free PMC Article

    09/14/2023
    LncRNA XIST Exacerbates Oxygen-Glucose Deprivation/Reoxygenation-Induced Cerebral Injury Through the miR-25-3p/TRAF3 Axis.

    LncRNA XIST Exacerbates Oxygen-Glucose Deprivation/Reoxygenation-Induced Cerebral Injury Through the miR-25-3p/TRAF3 Axis.
    Li Y, Zhang JK, Yu ZT, Jiang JW, Tang H, Tu GL, Xia Y.

    09/7/2023
    TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.

    TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
    Zheng W, Zhou Z, Rui Y, Ye R, Xia F, Guo F, Liu X, Su J, Lou M, Yu XF., Free PMC Article

    02/27/2023
    Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations.

    Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations.
    Rae W, Sowerby JM, Verhoeven D, Youssef M, Kotagiri P, Savinykh N, Coomber EL, Boneparth A, Chan A, Gong C, Jansen MH, du Long R, Santilli G, Simeoni I, Stephens J, Wu K, Zinicola M, Allen HL, Baxendale H, Kumararatne D, Gkrania-Klotsas E, Scheffler Mendoza SC, Yamazaki-Nakashimada MA, Ruiz LB, Rojas-Maruri CM, Lugo Reyes SO, Lyons PA, Williams AP, Hodson DJ, Bishop GA, Thrasher AJ, Thomas DC, Murphy MP, Vyse TJ, Milner JD, Kuijpers TW, Smith KGC.

    08/27/2022
    Circ_0050908 up-regulates TRAF3 by sponging miR-324-5p to aggravate myocardial ischemia-reperfusion injury.

    Circ_0050908 up-regulates TRAF3 by sponging miR-324-5p to aggravate myocardial ischemia-reperfusion injury.
    Jin A, Zhang Q, Cheng H, Yang C, Wang X.

    06/25/2022
    TRAF3 alterations are frequent in del-3'IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features.

    TRAF3 alterations are frequent in del-3'IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features.
    Pérez-Carretero C, Hernández-Sánchez M, González T, Quijada-Álamo M, Martín-Izquierdo M, Santos-Mínguez S, Miguel-García C, Vidal MJ, García-De-Coca A, Galende J, Pardal E, Aguilar C, Vargas-Pabón M, Dávila J, Gascón-Y-Marín I, Hernández-Rivas JÁ, Benito R, Hernández-Rivas JM, Rodríguez-Vicente AE.

    06/18/2022
    Hypoxic colorectal cancer-derived extracellular vesicles deliver microRNA-361-3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF-kappaB pathways.

    Hypoxic colorectal cancer-derived extracellular vesicles deliver microRNA-361-3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF-κB pathways.
    Li J, Yang P, Chen F, Tan Y, Huang C, Shen H, Peng C, Feng Y, Sun Y., Free PMC Article

    01/15/2022
    Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes.

    Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes.
    Liu Y, Gokhale S, Jung J, Zhu S, Luo C, Saha D, Guo JY, Zhang H, Kyin S, Zong WX, White E, Xie P., Free PMC Article

    01/8/2022
    Brief Research Report Regional Difference in TRAF2 and TRAF3 Gene Mutations in Colon Cancers.

    Brief Research Report Regional Difference in TRAF2 and TRAF3 Gene Mutations in Colon Cancers.
    Moon SW, Son HJ, Choi EJ, Yoo NJ, Lee SH., Free PMC Article

    01/8/2022
    RIP2 knockdown inhibits cartilage degradation and oxidative stress in IL-1beta-treated chondrocytes via regulating TRAF3 and inhibiting p38 MAPK pathway.

    RIP2 knockdown inhibits cartilage degradation and oxidative stress in IL-1β-treated chondrocytes via regulating TRAF3 and inhibiting p38 MAPK pathway.
    Pan D, Lyu Y, Zhang N, Wang X, Lei T, Liang Z.

    11/27/2021
    Identification of putative phenotype-modifying genetic factors associated with phenotypic diversity in Brooke-Spiegler syndrome.

    Identification of putative phenotype-modifying genetic factors associated with phenotypic diversity in Brooke-Spiegler syndrome.
    Pap ÉM, Farkas K, Széll M, Németh G, Rajan N, Nagy N.

    10/30/2021
    Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.

    Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
    Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y.

    10/2/2021
    TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-kappaB pathways.

    TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways.
    Zhou Y, Tao T, Liu G, Gao X, Gao Y, Zhuang Z, Lu Y, Wang H, Li W, Wu L, Zhang D, Hang C., Free PMC Article

    10/2/2021
    Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.

    Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.
    Lei Y, Cao X, Xu W, Yang B, Xu Y, Zhou W, Dong S, Wu Q, Rahman K, Tyagi R, Zhao S, Chen X, Cao G., Free PMC Article

    08/21/2021
    MicroRNA MiR-27a-5p Alleviates the Cerulein-Induced Cell Apoptosis and Inflammatory Injury of AR42J Cells by Targeting Traf3 in Acute Pancreatitis.

    MicroRNA MiR-27a-5p Alleviates the Cerulein-Induced Cell Apoptosis and Inflammatory Injury of AR42J Cells by Targeting Traf3 in Acute Pancreatitis.
    Zhu Y, Liu S, Wang F.

    07/17/2021
    Mechanism of inflammasome activation by SARS coronavirus 3a protein: abridged secondary publication.

    Mechanism of inflammasome activation by SARS coronavirus 3a protein: abridged secondary publication.
    Jin DY, Zheng BJ, Tang HMV.

    06/12/2021
    Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway.

    Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway.
    Liu HJ, Qin Y, Zhao ZH, Zhang Y, Yang JH, Zhai DH, Cui F, Luo C, Lu MX, Liu PP, Xu HW, Li K, Sun B, Chen S, Zhou HG, Yang C, Sun T., Free PMC Article

    06/5/2021
    Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-beta Production via Blocking the Interaction Between TRAF3 and TBK1.

    Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.
    Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J., Free PMC Article

    04/13/2021
    SHP-1 suppresses the antiviral innate immune response by targeting TRAF3.

    SHP-1 suppresses the antiviral innate immune response by targeting TRAF3.
    Hao D, Wang Y, Li L, Qian G, Liu J, Li M, Zhang Y, Zhou R, Yan D., Free PMC Article

    03/20/2021
    TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.

    TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.
    Whillock AL, Mambetsariev N, Lin WW, Stunz LL, Bishop GA., Free PMC Article

    11/21/2020
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