| Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum. | Higher-order structure and proteoforms of co-occurring C4b-binding protein assemblies in human serum.
Kadavá T, Hevler JF, Kalaidopoulou Nteak S, Yin VC, Strasser J, Preiner J, Heck AJ., Free PMC Article | 08/13/2024 |
| The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPalpha as a Biomarker to Predict Clopidogrel Resistance. | The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPα as a Biomarker to Predict Clopidogrel Resistance.
Xie HG, Jiang LP, Tai T, Ji JZ, Mi QY. | 03/19/2024 |
| Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein. | Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein.
Beirag N, Varghese PM, Neto MM, Al Aiyan A, Khan HA, Qablan M, Shamji MH, Sim RB, Temperton N, Kishore U., Free PMC Article | 07/7/2023 |
| Potential biomarkers of spinal dural arteriovenous fistula: C4BPA and C1QA. | Potential biomarkers of spinal dural arteriovenous fistula: C4BPA and C1QA.
Wang Y, Ma Y, Yang C, Huang X, Yang K, Lan F, Fu J, Song Z, Tian A, Feng Y, Tu T, Li H, Hong T, Wang Y, Zhang H., Free PMC Article | 07/2/2022 |
| The Hidden Side of Complement Regulator C4BP: Dissection and Evaluation of Its Immunomodulatory Activity. | The Hidden Side of Complement Regulator C4BP: Dissection and Evaluation of Its Immunomodulatory Activity.
Serrano I, Luque A, Mitjavila F, Blom AM, Rodríguez de Córdoba S, Vega MC, Torras J, Aran JM., Free PMC Article | 06/11/2022 |
| Immunoexpression of C4 Binding Protein in Oral Leukoplakia and Oral Squamous Cell Carcinoma. | Immunoexpression of C4 Binding Protein in Oral Leukoplakia and Oral Squamous Cell Carcinoma.
Mashhadiabbas F, Fayazi-Boroujeni M, Alizadeh A, Namdari M, Mirzaei SA. | 12/18/2021 |
| C4b-binding protein alpha-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer. | C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer.
Sasaki K, Takano S, Tomizawa S, Miyahara Y, Furukawa K, Takayashiki T, Kuboki S, Takada M, Ohtsuka M., Free PMC Article | 12/11/2021 |
| Observation of Complement Protein Gene Expression Before and After Surgery in Opioid-Consuming and Opioid-Naive Patients. | Observation of Complement Protein Gene Expression Before and After Surgery in Opioid-Consuming and Opioid-Naive Patients.
Johnson KB, Light AR, Odell DW, Stuart AR, Radtke J, Light KC. | 01/23/2021 |
| Fetal lung C4BPA induces p100 processing in human placenta. | Fetal lung C4BPA induces p100 processing in human placenta.
Ithier MC, Parobchak N, Yadava S, Cheng J, Wang B, Rosen T., Free PMC Article | 10/10/2020 |
| The authors conclude that Streptococcus pneumoniae PspA and PspC help the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b. | The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.
Haleem KS, Ali YM, Yesilkaya H, Kohler T, Hammerschmidt S, Andrew PW, Schwaeble WJ, Lynch NJ., Free PMC Article | 07/6/2019 |
| The rs73079108 polymorphism in the 5' upstream region of C4BPA was associated with EH, and rs73079108A may be an independent predictor. | Association of single nucleotide polymorphisms in the 5' upstream region of the C4BPA gene with essential hypertension in a northeastern Han Chinese population.
Liu X, Jiang C, Yang P., Free PMC Article | 04/7/2018 |
| INDEED also identified some candidates previously reported to be relevant to HCC, such as intercellular adhesion molecule 2 (ICAM2) and c4b-binding protein alpha chain (C4BPA), which were missed by both Differential expression and differential network analyses | INDEED: Integrated differential expression and differential network analysis of omic data for biomarker discovery.
Zuo Y, Cui Y, Di Poto C, Varghese RS, Yu G, Li R, Ressom HW., Free PMC Article | 01/20/2018 |
| Exposure to arterial blood pressure leads to a transient presence of C4bp in the saphenous vein wall. | Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts.
Kupreishvili K, Meischl C, Vonk ABA, Stooker W, Eijsman L, Blom AM, Quax PHA, van Hinsbergh VWM, Niessen HWM, Krijnen PAJ. | 12/16/2017 |
| Proteomics study showed a strong association of FN1, A2M, C4BPA and CFB in molecular subtypes of breast cancer, in which, C4BPA and A2M demonstrated a potent signature in blood plasma and tissue samples of Luminal-B (LB) and Triple-negative (TN)subtypes in BC patients, respectively. | Quantitative proteomics revealed novel proteins associated with molecular subtypes of breast cancer.
Suman S, Basak T, Gupta P, Mishra S, Kumar V, Sengupta S, Shukla Y. | 12/2/2017 |
| genetic polymorphism is associated with spontaneous abortion; review | C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend.
Ermert D, Blom AM. | 10/8/2016 |
| C4BP is deposited in the diseased aortic valve, coincident with C3d expression. | C4b-Binding Protein Deposition is Induced in Diseased Aortic Heart Valves, Coinciding with C3d.
Dikhoff MJ, ter Weeme M, Vonk AB, Kupreishvili K, Blom AM, Krijnen PA, Stooker W, Niessen HW. | 03/26/2016 |
| whereas the presence of plasminogen did not affect the factor I cofactor activity of C4BP, the activation of plasminogen by urokinase-type plasminogen activator to active plasmin was significantly augmented in the presence of C4BP. | A Novel Interaction between Complement Inhibitor C4b-binding Protein and Plasminogen That Enhances Plasminogen Activation.
Agarwal V, Talens S, Grandits AM, Blom AM., Free PMC Article | 10/24/2015 |
| C4BPB/C4BPA may not confer susceptibility to schizophrenia among Han Chinese | An evaluation of association between common variants in C4BPB/C4BPA genes and schizophrenia.
Wang S, Lu H, Ni J, Zhang J, Tang W, Lu W, Cai J, Zhang C. | 09/26/2015 |
| these data suggest that when C4BP is bound to Ail, fI can cleave and inactivate C4b that has bound covalently to bacterial surface structures as well as C4b bound noncovalently to Ail. | Yersinia pestis Ail recruitment of C4b-binding protein leads to factor I-mediated inactivation of covalently and noncovalently bound C4b.
Ho DK, Skurnik M, Blom AM, Meri S. | 07/12/2014 |
| In patients treated with tacrolimus and mycophenolate mophetil as a maintenance immunosuppression, the lower C4d urinary excretion in early post-transplant period seems to be a low significance prognostic marker of a better long-term kidney outcome. | [The early C4d urinary excretion and long-term kidney graft survival in patients treated with tacrolimus and mycophenolate mophetil].
Zwiech R. | 06/7/2014 |
| mutations in women experiencing recurrent miscarriages | Analysis of genes coding for CD46, CD55, and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy loss.
Mohlin FC, Mercier E, Fremeaux-Bacchi V, Liszewski MK, Atkinson JP, Gris JC, Blom AM., Free PMC Article | 09/7/2013 |
| The heptameric core structure is stabilized by intermolecular disulfide bonds. | Arranged sevenfold: structural insights into the C-terminal oligomerization domain of human C4b-binding protein.
Hofmeyer T, Schmelz S, Degiacomi MT, Dal Peraro M, Daneschdar M, Scrima A, van den Heuvel J, Heinz DW, Kolmar H. | 05/25/2013 |
| C4BP alpha7beta0 isoform complement control protein-6 domain of C4BP alpha-chain is necessary for tolerogenic activity of the acute-phase C4BPbeta chain. | The α7β0 isoform of the complement regulator C4b-binding protein induces a semimature, anti-inflammatory state in dendritic cells.
Olivar R, Luque A, Naranjo-Gómez M, Quer J, García de Frutos P, Borràs FE, Rodríguez de Córdoba S, Blom AM, Aran JM. | 05/18/2013 |
| The Lsa30 (LIC110870) is a novel adhesin that binds plasminogen and the complement regulator C4bp. | Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp.
Souza NM, Vieira ML, Alves IJ, de Morais ZM, Vasconcellos SA, Nascimento AL. | 01/26/2013 |
| Human pneumococcal glycolytic enzyme enolase, a nonclassical cell surface and plasminogen-binding protein, is a pneumococcal C4BP-binding protein. | Enolase of Streptococcus pneumoniae binds human complement inhibitor C4b-binding protein and contributes to complement evasion.
Agarwal V, Hammerschmidt S, Malm S, Bergmann S, Riesbeck K, Blom AM. | 12/8/2012 |