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    SNHG4 small nucleolar RNA host gene 4 [ Homo sapiens (human) ]

    Gene ID: 724102, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.

    lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.
    Li SQ, Lv F, Xu WT, Yin YX, Wei HT, Li KZ, Hu BL.

    06/3/2024
    SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.

    SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
    Li SQ, Xu WT, Yin YX, Wei HT, Li KZ, Xie MZ, Lv F, Xie LY, Hu BL.

    05/8/2024
    Long non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis.

    Long non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis.
    Song B, Chen Y., Free PMC Article

    12/29/2023
    Long Non-Coding RNA Small Nucleolar RNA Host Gene 4 Induced by Transcription Factor SP1 Promoted the Progression of Nasopharyngeal Carcinoma Through Modulating microRNA-510-5p/Centromere Protein F Axis.

    Long Non-Coding RNA Small Nucleolar RNA Host Gene 4 Induced by Transcription Factor SP1 Promoted the Progression of Nasopharyngeal Carcinoma Through Modulating microRNA-510-5p/Centromere Protein F Axis.
    Zhou S, Cao C, Hu J.

    09/25/2023
    LncRNA SNHG4 sponges miR-200b to inhibit cell apoptosis in diabetic retinopathy.

    LncRNA SNHG4 sponges miR-200b to inhibit cell apoptosis in diabetic retinopathy.
    Yu J, Qin M, Li J, Cui S.

    09/19/2023
    LncRNA SNHG4 promotes prostate cancer cell survival and resistance to enzalutamide through a let-7a/RREB1 positive feedback loop and a ceRNA network.

    LncRNA SNHG4 promotes prostate cancer cell survival and resistance to enzalutamide through a let-7a/RREB1 positive feedback loop and a ceRNA network.
    Dong Q, Qiu H, Piao C, Li Z, Cui X., Free PMC Article

    08/28/2023
    Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR-211-5p/CREB5 axis.

    Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR-211-5p/CREB5 axis.
    Qiu J, Wang P, Chen Z, Zhou Y, Zhang G, Wang Z, Wu J, Zhu Q, Jiang C., Free PMC Article

    05/4/2023
    Long Non-Coding RNA SNHG4 Expression in Women with Endometriosis: A Pilot Study.

    Long Non-Coding RNA SNHG4 Expression in Women with Endometriosis: A Pilot Study.
    Szaflik T, Romanowicz H, Szyłło K, Smolarz B., Free PMC Article

    02/14/2023
    Regulatory Effects of LncRNA SNHG4 on miR-25/FBXW7 Axis in Papillary Thyroid Cancer Cells.

    Regulatory Effects of LncRNA SNHG4 on miR-25/FBXW7 Axis in Papillary Thyroid Cancer Cells.
    Lan H.

    09/3/2022
    Long Non-Coding RNA SNHG4 Is a Potential Diagnostic and Prognostic Indicator in Non-Small Cell Lung Cancer.

    Long Non-Coding RNA SNHG4 Is a Potential Diagnostic and Prognostic Indicator in Non-Small Cell Lung Cancer.
    Li Z, Zhuo Y, Li J, Zhang M, Wang R, Lin L.

    02/12/2022
    Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 - Mediated m(6)A level of STAT2 mRNA.

    Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 - Mediated m(6)A level of STAT2 mRNA.
    Li SX, Yan W, Liu JP, Zhao YJ, Chen L.

    11/6/2021
    LncRNA SNHG4 regulates miR-138/c-Met axis to promote the proliferation of glioblastoma cells.

    LncRNA SNHG4 regulates miR-138/c-Met axis to promote the proliferation of glioblastoma cells.
    Wang X, Tian W, Wu L, Wei Z, Li W, Xu Y, Li Y.

    08/21/2021
    LncRNA SNHG4 Attenuates Inflammatory Responses by Sponging miR-449c-5p and Up-Regulating STAT6 in Microglial During Cerebral Ischemia-Reperfusion Injury.

    LncRNA SNHG4 Attenuates Inflammatory Responses by Sponging miR-449c-5p and Up-Regulating STAT6 in Microglial During Cerebral Ischemia-Reperfusion Injury.
    Zhang S, Sun WC, Liang ZD, Yin XR, Ji ZR, Chen XH, Wei MJ, Pei L., Free PMC Article

    07/10/2021
    LncRNA SNHG4 promotes the increased growth of endometrial tissue outside the uterine cavity via regulating c-Met mediated by miR-148a-3p.

    LncRNA SNHG4 promotes the increased growth of endometrial tissue outside the uterine cavity via regulating c-Met mediated by miR-148a-3p.
    Liu Y, Huang X, Lu D, Feng Y, Xu R, Li X, Yin C, Xue B, Zhao H, Wang S, Ma Y, Jia C.

    06/5/2021
    LncRNA SNHG4 promotes osteosarcoma proliferation and migration by sponging miR-377-3p.

    LncRNA SNHG4 promotes osteosarcoma proliferation and migration by sponging miR-377-3p.
    Huang YF, Lu L, Shen HL, Lu XX., Free PMC Article

    05/15/2021
    lncRNA SNHG4 promotes cell proliferation, migration, invasion and the epithelial-mesenchymal transition process via sponging miR-204-5p in gastric cancer.

    lncRNA SNHG4 promotes cell proliferation, migration, invasion and the epithelial-mesenchymal transition process via sponging miR-204-5p in gastric cancer.
    Wang S, Zhu W, Qiu J, Chen F., Free PMC Article

    05/8/2021
    SP1-mediated upregulation of lncRNA SNHG4 functions as a ceRNA for miR-377 to facilitate prostate cancer progression through regulation of ZIC5.

    SP1-mediated upregulation of lncRNA SNHG4 functions as a ceRNA for miR-377 to facilitate prostate cancer progression through regulation of ZIC5.
    Wang ZY, Duan Y, Wang P.

    02/6/2021
    LncRNA SNHG4 promotes neuroblastoma proliferation, migration, and invasion by sponging miR-377-3p.

    LncRNA SNHG4 promotes neuroblastoma proliferation, migration, and invasion by sponging miR-377-3p.
    Yang H, Guo JF, Zhang ML, Li AM.

    12/19/2020
    LncRNA SNHG4 regulates miR-10a/PTEN to inhibit the proliferation of acute myeloid leukemia cells.

    LncRNA SNHG4 regulates miR-10a/PTEN to inhibit the proliferation of acute myeloid leukemia cells.
    Yuan Z, Wang W.

    11/21/2020
    findings demonstrate that SNHG4 is required by lung cancer cells to maintain malignant phenotype; SNHG4 probably exerts its pro-survival and pro-metastatic effects by sponging anti-tumor miR-98-5p

    LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
    Tang Y, Wu L, Zhao M, Zhao G, Mao S, Wang L, Liu S, Wang X.

    03/28/2020
    Snhg4-pod was detected in urinary sediments from PAN-induced nephrotic rats. Our findings suggest that Snhg4-pod may serve as a novel marker for the diagnosis of glomerular injury

    A novel splicing variant of small nucleolar RNA host gene 4 is a podocyte-selective non-coding RNA upregulated in response to puromycin aminonucleoside-induced podocyte injury.
    Horikawa A, Yoneda T, Yaoita E, Yamaguchi K, Shigenobu S, Kuramochi M, Yamate J, Inui T, Ishibashi O.

    06/1/2019
    demonstrated that LncRNA SNHG4 promoted tumour growth by sponging miR-224-3p and represented a poor prognostic factor in patients with osteosarcoma

    LncRNA SNHG4 promotes tumour growth by sponging miR-224-3p and predicts poor survival and recurrence in human osteosarcoma.
    Xu R, Feng F, Yu X, Liu Z, Lao L., Free PMC Article

    12/22/2018
    Observational study of gene-disease association. (HuGE Navigator)

    Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.
    Graubert TA, Payton MA, Shao J, Walgren RA, Monahan RS, Frater JL, Walshauser MA, Martin MG, Kasai Y, Walter MJ., Free PMC Article

    03/25/2009
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