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    TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]

    Gene ID: 7253, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TSHR-IGF-IR complex drives orbital fibroblast misbehavior in thyroid eye disease.

    TSHR-IGF-IR complex drives orbital fibroblast misbehavior in thyroid eye disease.
    Smith TJ.

    09/12/2024
    A Novel TSHR Gene Mutation in a Family with Non-autoimmune Hyperthyroidism.

    A Novel TSHR Gene Mutation in a Family with Non-autoimmune Hyperthyroidism.
    Kufoof T, Luxford C, Kannangara K, Clifton-Bligh R, Donaghue KC., Free PMC Article

    04/5/2024
    TSHR Variant Screening and Phenotype Analysis in 367 Chinese Patients With Congenital Hypothyroidism.

    TSHR Variant Screening and Phenotype Analysis in 367 Chinese Patients With Congenital Hypothyroidism.
    Zhang HY, Wu FY, Li XS, Tu PH, Zhang CX, Yang RM, Cui RJ, Wu CY, Fang Y, Yang L, Song HD, Zhao SX., Free PMC Article

    03/28/2024
    Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T-knockin model.

    Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T-knockin model.
    Makkonen K, Jännäri M, Crisóstomo L, Kuusi M, Patyra K, Melnyk V, Linnossuo V, Ojala J, Ravi R, Löf C, Mäkelä JA, Miettinen P, Laakso S, Ojaniemi M, Jääskeläinen J, Laakso M, Bossowski F, Sawicka B, Stożek K, Bossowski A, Kleinau G, Scheerer P, FinnGen F, Reeve MP, Kero J., Free PMC Article

    02/24/2024
    Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone Receptor Expression in Oncocytic Thyroid Neoplasms: Implications for Prognosis and Treatment.

    Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone Receptor Expression in Oncocytic Thyroid Neoplasms: Implications for Prognosis and Treatment.
    Gillis A, Zheng-Pywell R, McLeod C, Wang D, Ness JM, Guenter R, Whitt J, Prolla TA, Chen H, Gonzalez ML, Rose B, Lloyd RV, Jaskula-Sztul R, Lin D.,

    01/3/2024
    Molecular investigation of TSHR gene in Bangladeshi congenital hypothyroid patients.

    Molecular investigation of TSHR gene in Bangladeshi congenital hypothyroid patients.
    Begum MN, Mahtarin R, Islam MT, Ahmed S, Konika TK, Mannoor K, Akhteruzzaman S, Qadri F., Free PMC Article

    08/16/2023
    Eighteen-years follow-up of congenital hypothyroidism by TSHR gene p.Arg109Gln and p.Arg450His variants.

    Eighteen-years follow-up of congenital hypothyroidism by TSHR gene p.Arg109Gln and p.Arg450His variants.
    Watanabe D, Yagasaki H, Mitsui Y, Inukai T., Free PMC Article

    06/28/2023
    Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens.

    Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens.
    Andrianus S, Gubbiotti MA, Mandel SJ, Nikiforov YE, Baloch Z., Free PMC Article

    06/7/2023
    [Pathogenic TSHR variants in children with thyroid dysgenesis].

    [Pathogenic TSHR variants in children with thyroid dysgenesis].
    Shreder EV, Vadina TA, Solodovnikova EN, Zakharova VV, Degtyarev MV, Konyukhova MB, Sergeeva NV, Bezlepkina OB., Free PMC Article

    03/1/2023
    Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations.

    Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations.
    Whitmer D, Phay JE, Holt S, O'Donnell B, Nguyen J, Joseph D, Chi A, Wu S, Hao Y, Huang J, Klopper JP, Kloos RT, Kennedy GC, Shin J., Free PMC Article

    01/14/2023
    Autoantibody mimicry of hormone action at the thyrotropin receptor.

    Autoantibody mimicry of hormone action at the thyrotropin receptor.
    Faust B, Billesbølle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A., Free PMC Article

    10/8/2022
    Hormone- and antibody-mediated activation of the thyrotropin receptor.

    Hormone- and antibody-mediated activation of the thyrotropin receptor.
    Duan J, Xu P, Luan X, Ji Y, He X, Song N, Yuan Q, Jin Y, Cheng X, Jiang H, Zheng J, Zhang S, Jiang Y, Xu HE.

    10/8/2022
    Association of TSHR gene single nucleotide intronic polymorphism with the risk of hypothyroid and hyperthyroid disorders in Yazd province.

    Association of TSHR gene single nucleotide intronic polymorphism with the risk of hypothyroid and hyperthyroid disorders in Yazd province.
    Naghibi FS, Miresmaeili SM, Javid A., Free PMC Article

    10/1/2022
    Brief Report - Monoclonal Antibodies Illustrate the Difficulties in Measuring Blocking TSH Receptor Antibodies.

    Brief Report - Monoclonal Antibodies Illustrate the Difficulties in Measuring Blocking TSH Receptor Antibodies.
    Davies TF, Morshed SA, Mezei M, Latif R., Free PMC Article

    08/6/2022
    The Mysterious Universe of the TSH Receptor.

    The Mysterious Universe of the TSH Receptor.
    Vieira IH, Rodrigues D, Paiva I., Free PMC Article

    08/6/2022
    TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.

    TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.
    Jang D, Eliseeva E, Klubo-Gwiezdzinska J, Neumann S, Gershengorn MC., Free PMC Article

    04/9/2022
    Presence of TSHR in NK Cells and Action of TSH on NK Cells.

    Presence of TSHR in NK Cells and Action of TSH on NK Cells.
    Yang Q, Li J, Kou C, Zhang L, Wang X, Long Y, Ni J, Li S, Zhang H.

    03/12/2022
    Differentiation of benign thyroid nodules from malignant thyroid nodules through miR-205-5p and thyroid-stimulating hormone receptor mRNA.

    Differentiation of benign thyroid nodules from malignant thyroid nodules through miR-205-5p and thyroid-stimulating hormone receptor mRNA.
    Zhou J, Cao L, Chen Z.

    03/5/2022
    Thyrotropin Receptor p.N432D Retained Variant Is Degraded Through an Alternative Lysosomal/Autophagosomal Pathway and Can Be Functionally Rescued by Chemical Chaperones.

    Thyrotropin Receptor p.N432D Retained Variant Is Degraded Through an Alternative Lysosomal/Autophagosomal Pathway and Can Be Functionally Rescued by Chemical Chaperones.
    Grassi ES, Lábadi A, Vezzoli V, Ghiandai V, Bonomi M, Persani L.

    01/8/2022
    Implications of an Improved Model of the TSH Receptor Transmembrane Domain (TSHR-TMD-TRIO).

    Implications of an Improved Model of the TSH Receptor Transmembrane Domain (TSHR-TMD-TRIO).
    Mezei M, Latif R, Das B, Davies TF., Free PMC Article

    10/9/2021
    New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism.

    New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism.
    Caron P, Broussaud S, Galano-Frutos JJ, Sancho J, Savagner F.

    09/25/2021
    Inactivation of a Frameshift TSH Receptor Variant Val711Phefs*18 is Due to Acquisition of a Hydrophobic Degron.

    Inactivation of a Frameshift TSH Receptor Variant Val711Phefs*18 is Due to Acquisition of a Hydrophobic Degron.
    Sugisawa C, Ono M, Kashimada K, Hasegawa T, Narumi S.

    09/4/2021
    Relationship between TSHR, BRAF and PIK3CA gene copy number variations and thyroid nodules.

    Relationship between TSHR, BRAF and PIK3CA gene copy number variations and thyroid nodules.
    Shi X, Qu M, Jin X, Liu L, Meng F, Shen H.

    09/4/2021
    Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.

    Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.
    Benvenga S, Guarneri F.

    06/19/2021
    The Human TSHbeta Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation.

    The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation.
    Mezei M, Baliram R, Ali MR, Zaidi M, Davies TF, Latif R., Free PMC Article

    01/9/2021
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