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    MUC5B mucin 5B, oligomeric mucus/gel-forming [ Homo sapiens (human) ]

    Gene ID: 727897, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Sialylated keratan sulfates on MUC5B are Siglec-8 ligands in the human esophagus.

    Sialylated keratan sulfates on MUC5B are Siglec-8 ligands in the human esophagus.
    Li TA, Gonzalez-Gil A, Awol AK, Ackerman SJ, Orsburn BC, Schnaar RL.,

    09/5/2024
    Hyposecretion of cervical MUC5B is related to preterm birth in pregnant women after cervical excisional surgery.

    Hyposecretion of cervical MUC5B is related to preterm birth in pregnant women after cervical excisional surgery.
    Ueda Y, Mogami H, Chigusa Y, Kawamura Y, Inohaya A, Takakura M, Yasuda E, Matsuzaka Y, Shimada M, Ito S, Morita S, Mandai M, Kondoh E.

    03/14/2024
    Association of MUC5B promoter polymorphism with interstitial lung changes after COVID-19: A preliminary observation.

    Association of MUC5B promoter polymorphism with interstitial lung changes after COVID-19: A preliminary observation.
    Dhooria S, Bal A, Sharma R, Prabhakar N, Arora S, Sehgal IS, Kashyap D, Garg M, Bhalla A, Aggarwal AN, Agarwal R., Free PMC Article

    03/6/2024
    Elucidating the molecular role of MUC5B in progressive lung adenocarcinoma: Prospects for early diagnosis.

    Elucidating the molecular role of MUC5B in progressive lung adenocarcinoma: Prospects for early diagnosis.
    Ashok G, Soundararajan A, Anbarasu A, Ramaiah S.

    01/6/2024
    The Presence of T Allele (rs35705950) of the MUC5B Gene Predicts Lower Baseline Forced Vital Capacity and Its Subsequent Decline in Patients with Hypersensitivity Pneumonitis.

    The Presence of T Allele (rs35705950) of the MUC5B Gene Predicts Lower Baseline Forced Vital Capacity and Its Subsequent Decline in Patients with Hypersensitivity Pneumonitis.
    Lewandowska KB, Szturmowicz M, Lechowicz U, Franczuk M, Błasińska K, Falis M, Błaszczyk K, Sobiecka M, Wyrostkiewicz D, Siemion-Szcześniak I, Bartosiewicz M, Radwan-Röhrenschef P, Roży A, Chorostowska-Wynimko J, Tomkowski WZ., Free PMC Article

    09/11/2023
    The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

    The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.
    Khorasani AM, Mohammadi B, Saghafi MR, Mohammadi S, Ghaffari S, Mirsadraee M, Khakzad MR.

    05/23/2023
    MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study.

    MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study.
    Kim JS, Manichaikul AW, Hoffman EA, Balte P, Anderson MR, Bernstein EJ, Madahar P, Oelsner EC, Kawut SM, Wysoczanski A, Laine AF, Adegunsoye A, Ma JZ, Taub MA, Mathias RA, Rich SS, Rotter JI, Noth I, Garcia CK, Barr RG, Podolanczuk AJ., Free PMC Article

    05/18/2023
    MUC5B rs35705950 minor allele associates with older age and better survival in idiopathic pulmonary fibrosis.

    MUC5B rs35705950 minor allele associates with older age and better survival in idiopathic pulmonary fibrosis.
    van der Vis JJ, Prasse A, Renzoni EA, Stock CJW, Caliskan C, Maher TM, Bonella F, Borie R, Crestani B, Petrek M, Wuyts WA, Wind AE, Molyneaux PL, Grutters JC, van Moorsel CHM.

    04/19/2023
    Are MUC5B and TERT mutations genetic risk factors for pulmonary fibrosis in individuals with severe COVID-19?

    Are MUC5B and TERT mutations genetic risk factors for pulmonary fibrosis in individuals with severe COVID-19?
    Yetkin NA, Kiraz A, Baran Ketencioğlu B, Bol C, Tutar N., Free PMC Article

    03/14/2023
    Salivary film thickness and MUC5B levels at various intra-oral surfaces.

    Salivary film thickness and MUC5B levels at various intra-oral surfaces.
    Assy Z, Jager DHJ, Brand HS, Bikker FJ., Free PMC Article

    02/11/2023
    Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

    Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.
    Baumlin N, Silswal N, Dennis JS, Niloy AJ, Kim MD, Salathe M., Free PMC Article

    02/4/2023
    MUC5B Promoter Polymorphism and Survival in Indian Patients With Idiopathic Pulmonary Fibrosis.

    MUC5B Promoter Polymorphism and Survival in Indian Patients With Idiopathic Pulmonary Fibrosis.
    Dhooria S, Bal A, Sehgal IS, Prasad KT, Kashyap D, Sharma R, Muthu V, Agarwal R, Aggarwal AN.

    01/11/2023
    MUC5B promoter variant rs35705950, rare but significant susceptibility locus in rheumatoid arthritis-interstitial lung disease with usual interstitial pneumonia in Asian populations.

    MUC5B promoter variant rs35705950, rare but significant susceptibility locus in rheumatoid arthritis-interstitial lung disease with usual interstitial pneumonia in Asian populations.
    Joo YB, Ahn SM, Bang SY, Park Y, Hong SJ, Lee Y, Cho SK, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Bae SC, Lee HS., Free PMC Article

    01/11/2023
    Radiological Assessment in Idiopathic Pulmonary Fibrosis (IPF) Patients According to MUC5B Polymorphism.

    Radiological Assessment in Idiopathic Pulmonary Fibrosis (IPF) Patients According to MUC5B Polymorphism.
    Cocconcelli E, Bernardinello N, Giraudo C, Castelli G, Greco C, Polverosi R, Saetta M, Spagnolo P, Balestro E., Free PMC Article

    01/11/2023
    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.
    Song D, Iverson E, Kaler L, Boboltz A, Scull MA, Duncan GA., Free PMC Article

    12/24/2022
    De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

    De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.
    Vial Y, Lainey E, Leblanc T, Baudouin V, Dourthe ME, Gressens P, Verloes A, Cavé H, Drunat S.

    12/3/2022
    Associations of the MUC5B promoter variant with timing of interstitial lung disease and rheumatoid arthritis onset.

    Associations of the MUC5B promoter variant with timing of interstitial lung disease and rheumatoid arthritis onset.
    McDermott G, Gill R, Gagne S, Byrne S, Huang W, Cui J, Prisco L, Zaccardelli A, Martin L, Kronzer VL, Moll M, Cho MH, Shadick N, Dellaripa PF, Doyle T, Sparks JA., Free PMC Article

    12/3/2022
    A review on the role of salivary MUC5B in oral health.

    A review on the role of salivary MUC5B in oral health.
    Faruque M, Wanschers M, Ligtenberg AJ, Laine ML, Bikker FJ.

    11/26/2022
    Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.

    Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.
    Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV., Free PMC Article

    11/26/2022
    A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality.

    A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality.
    Verma A, Minnier J, Wan ES, Huffman JE, Gao L, Joseph J, Ho YL, Wu WC, Cho K, Gorman BR, Rajeevan N, Pyarajan S, Garcon H, Meigs JB, Sun YV, Reaven PD, McGeary JE, Suzuki A, Gelernter J, Lynch JA, Petersen JM, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Gatsby E, Lynch KE, Bonomo RA, Freiberg M, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Wilson PWF, Hung AM, O'Donnell CJ, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW, Million Veteran Program COVID-19 Science Initiative., Free PMC Article

    11/26/2022
    Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

    Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.
    Hoang ON, Ermund A, Jaramillo AM, Fakih D, French CB, Flores JR, Karmouty-Quintana H, Magnusson JM, Fois G, Fauler M, Frick M, Braubach P, Hales JB, Kurten RC, Panettieri R, Vergara L, Ehre C, Adachi R, Tuvim MJ, Hansson GC, Dickey BF., Free PMC Article

    11/5/2022
    A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease.

    A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease.
    Juge PA, Granger B, Debray MP, Ebstein E, Louis-Sidney F, Kedra J, Doyle TJ, Borie R, Constantin A, Combe B, Flipo RM, Mariette X, Vittecoq O, Saraux A, Carvajal-Alegria G, Sibilia J, Berenbaum F, Kannengiesser C, Boileau C, Sparks JA, Crestani B, Fautrel B, Dieudé P., Free PMC Article

    11/5/2022
    Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains.

    Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains.
    Chahal G, Quintana-Hayashi MP, Gaytán MO, Benktander J, Padra M, King SJ, Linden SK., Free PMC Article

    07/16/2022
    The MUC5B Promoter Polymorphism is Not Associated With Non-ILD Chronic Respiratory Diseases or Post-transplant Outcome.

    The MUC5B Promoter Polymorphism is Not Associated With Non-ILD Chronic Respiratory Diseases or Post-transplant Outcome.
    Goos T, Verleden SE, De Sadeleer LJ, Van Herck A, Sacreas A, Vanstapel A, Kaes J, Geudens V, Aelbrecht C, Ruttens D, Lambrechts D, Vermeer S, Ceulemans LJ, Van Raemdonck DE, Godinas L, Yserbyt J, Vanaudenaerde BM, Verleden GM, Vos R, Wuyts WA., Free PMC Article

    06/11/2022
    Role of MUC5B during Group B Streptococcal Vaginal Colonization.

    Role of MUC5B during Group B Streptococcal Vaginal Colonization.
    Burcham LR, Bath JR, Werlang CA, Lyon LM, Liu N, Evans C, Ribbeck K, Doran KS., Free PMC Article

    05/7/2022
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