Digenic FLNA and UCHL1 variants resulting in a complex phenotype.
Pernice HF, O'Donnell LF, Rossor AM, Laura M, Record CJ, Skorupinska M, Blake J, Poh R, Polke J, Reilly MM.

UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas.
Liu S, Chai T, Garcia-Marques F, Yin Q, Hsu EC, Shen M, Shaw Toland AM, Bermudez A, Hartono AB, Massey CF, Lee CS, Zheng L, Baron M, Denning CJ, Aslan M, Nguyen HM, Nolley R, Zoubeidi A, Das M, Kunder CA, Howitt BE, Soh HT, Weissman IL, Liss MA, Chin AI, Brooks JD, Corey E, Pitteri SJ, Huang J, Stoyanova T., Free PMC Article

Changes in Serum LncRNA MEG3/miR-181b and UCH-L1 Levels in Patients with Moderate and Severe Intracerebral Hemorrhage.
Wang H, Wang L, Shi Q.

Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells.
Wu DD, Lau ATY, Xu YM, Reinders-Luinge M, Koncz M, Kiss A, Timens W, Rots MG, Hylkema MN., Free PMC Article

Elevated cerebrospinal fluid ubiquitin C-terminal hydrolase-L1 levels correlate with phenotypic severity and therapeutic response in Niemann-Pick disease, type C1.
Cawley NX, Giddens S, Farhat NM, Luke RA, Scott KEJ, Mohamed HO, Dang Do A, Berry-Kravis E, Cologna SM, Liu F, Porter FD.,

UCHL1-PKM2 axis dysregulation is associated with promoted proliferation and invasiveness of urothelial bladder cancer cells.
Zheng Y, Shi D, Chen L, Yang Y, Yao M., Free PMC Article

UCHL1 facilitates protein aggregates clearance to enhance neural stem cell activation in spinal cord injury.
Ding L, Chu W, Xia Y, Shi M, Li T, Zhou FQ, Deng DYB., Free PMC Article

Ubiquitin C-terminal hydrolase L1 after out-of-hospital cardiac arrest.
Wihersaari L, Reinikainen M, Tiainen M, Bendel S, Kaukonen KM, Vaahersalo J, Romppanen J, Pettilä V, Skrifvars MB, FINNRESUSCI Study Group.

UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid.
Guo C, Liang L, Zheng J, Xie Y, Qiu X, Tan G, Huang J, Wang L.

Associations of blood UCH-L1 and NfL levels with cognitive dysfunction in Parkinson's disease patients.
Dong L, Chang Q, Ma J, Liu C, Guo D, Li X, Yang D, Fan Y, Liang K, Li D, Gu Q.

Ubiquitin C-terminal hydrolase 1 is increased in migraine attack.
Atescelik M, Yilmaz M.

Role of UCHL1 in the pathogenesis of neurodegenerative diseases and brain injury.
Mi Z, Graham SH., Free PMC Article

Pivotal Role of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) in Uterine Leiomyoma.
Suzuki T, Dai Y, Ono M, Kojima J, Sasaki T, Fujiwara H, Kuji N, Nishi H., Free PMC Article

UCHL1 promotes cancer stemness in triple-negative breast cancer.
Tian C, Liu Y, Liu Y, Hu P, Xie S, Guo Y, Wang H, Zhang Z, Du L, Lei B, Wang Y, Xue L, Zhang D, Su J, Zhang X, Zhang R, Chen J, Zhang X, Chen L, Li M, Jia Q, Song J, Liu J.

MMP-1, UCH-L1, and 20S Proteasome as Potential Biomarkers Supporting the Diagnosis of Brain Glioma.
Oldak L, Chludzinska-Kasperuk S, Milewska P, Grubczak K, Reszec J, Gorodkiewicz E., Free PMC Article

Structural basis for specific inhibition of the deubiquitinase UCHL1.
Grethe C, Schmidt M, Kipka GM, O'Dea R, Gallant K, Janning P, Gersch M., Free PMC Article

Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy.
Park J, Tucci A, Cipriani V, Demidov G, Rocca C, Senderek J, Butryn M, Velic A, Lam T, Galanaki E, Cali E, Vestito L, Maroofian R, Deininger N, Rautenberg M, Admard J, Hahn GA, Bartels C, van Os NJH, Horvath R, Chinnery PF, Tiet MY, Hewamadduma C, Hadjivassiliou M, Tofaris GK, Genomics England Research Consortium, Wood NW, Hayer SN, Bender F, Menden B, Cordts I, Klein K, Nguyen HP, Krauss JK, Blahak C, Strom TM, Sturm M, van de Warrenburg B, Lerche H, Maček B, Synofzik M, Ossowski S, Timmann D, Wolf ME, Smedley D, Riess O, Schöls L, Houlden H, Haack TB, Hengel H.

Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study.
Korley FK, Jain S, Sun X, Puccio AM, Yue JK, Gardner RC, Wang KKW, Okonkwo DO, Yuh EL, Mukherjee P, Nelson LD, Taylor SR, Markowitz AJ, Diaz-Arrastia R, Manley GT, TRACK-TBI Study Investigators., Free PMC Article

Ubiquitin carboxyl-terminal esterase L1 is not elevated in the serum of concussed rugby players: an observational cross-sectional study.
Harrell JO, Morgan JE, Beck SD, Scobercea IC, Baker JS, Knox A, Serrador JM, Rogatzki MJ., Free PMC Article

Predicting Clinical Outcomes 7-10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2.
Svingos AM, Robicsek SA, Hayes RL, Wang KK, Robertson CS, Brophy GM, Papa L, Gabrielli A, Hannay HJ, Bauer RM, Heaton SC.

Association of Ubiquitin C-Terminal Hydrolase-L1 (Uch-L1) serum levels with cognition and brain energy metabolism.
Zhang M, Chen MY, Wang SL, Ding XM, Yang R, Li J, Jiang GH.

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma.
Yao J, Reyimu A, Sun A, Duoji Z, Zhou W, Liang S, Hu S, Wang X, Dai J, Xu X., Free PMC Article

UCHL1 promotes proliferation and metastasis in head and neck squamous cell carcinoma and could be a potential therapeutic target.
Zhang D, Fu Y, Tian G, Li J, Shang D, Zhou S.

UCHL1 protects against ischemic heart injury via activating HIF-1α signal pathway.
Geng B, Wang X, Park KH, Lee KE, Kim J, Chen P, Zhou X, Tan T, Yang C, Zou X, Janssen PM, Cao L, Ye L, Wang X, Cai C, Zhu H., Free PMC Article

Ubiquitin C-terminal hydrolase L1 promotes lymph node metastasis in small cell neuroendocrine carcinomas of the cervix.
Zhang Y, Ding J, Zhang X, Hua K., Free PMC Article