| Exploring WNT2 polymorphisms in comitant strabismus: A genetic association study. | Exploring WNT2 polymorphisms in comitant strabismus: A genetic association study.
Zehra Z, von Bartheld CS, Agarwal AB, Vasquez-Gross H, Noorani Siddiqui S, Azam M, Qamar R. | 08/19/2024 |
| A translational exploration of the effects of WNT2 variants on altered cortical structures in autism spectrum disorder. | A translational exploration of the effects of WNT2 variants on altered cortical structures in autism spectrum disorder.
Chien YL, Chen YC, Chiu YN, Tsai WC, Gau SS., Free PMC Article | 06/18/2022 |
| WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas. | WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas.
Aavikko M, Kaasinen E, Andersson N, Pentinmikko N, Sulo P, Donner I, Pihlajamaa P, Kuosmanen A, Bramante S, Katainen R, Sipilä LJ, Martin S, Arola J, Carpén O, Heiskanen I, Mecklin JP, Taipale J, Ristimäki A, Lehti K, Gucciardo E, Katajisto P, Schalin-Jäntti C, Vahteristo P, Aaltonen LA., Free PMC Article | 04/16/2022 |
| Overexpression of IL-8 and Wnt2 is associated with prognosis of gastric cancer. | Overexpression of IL-8 and Wnt2 is associated with prognosis of gastric cancer.
Lin L, Li L, Ma G, Kang Y, Wang X, He J. | 03/26/2022 |
| Distinguishing colorectal adenoma from hyperplastic polyp by WNT2 expression. | Distinguishing colorectal adenoma from hyperplastic polyp by WNT2 expression.
Wang B, Wang X, Tseng Y, Huang M, Luo F, Zhang J, Liu J., Free PMC Article | 02/5/2022 |
| LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p. | LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p.
Jin L, Luo C, Wu X, Li M, Wu S, Feng Y., Free PMC Article | 01/15/2022 |
| Prognostic Significance of Wnt1, Wnt2, E-Cadherin, and beta-catenin Expression in Operable Non-small Cell Lung Cancer. | Prognostic Significance of Wnt1, Wnt2, E-Cadherin, and β-catenin Expression in Operable Non-small Cell Lung Cancer.
Wrona A, Sejda A, Dziadziuszko R, Jassem J., Free PMC Article | 12/11/2021 |
| Involvement of WNT2 in trophoblast cell behavior in preeclampsia development. | Involvement of WNT2 in trophoblast cell behavior in preeclampsia development.
Liu Y, Huang J, Yu N, Wei S, Liu Z., Free PMC Article | 09/4/2021 |
| MiR-548b suppresses proliferative capacity of colorectal cancer by binding WNT2. | MiR-548b suppresses proliferative capacity of colorectal cancer by binding WNT2.
Xu Y, Zhong YD, Zhao XX. | 06/26/2021 |
| The increased expression of DKK1 and decreased expression of WNT2 may be involved in the pathogenesis of early-onset preeclampsia | Altered DNA methylation and transcription of WNT2 and DKK1 genes in placentas associated with early-onset preeclampsia.
Zhang L, Leng M, Li Y, Yuan Y, Yang B, Li Y, Yuan E, Shi W, Yan S, Cui S. | 03/23/2019 |
| Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway through inhibition of Wnt2 and Fzd2. | Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway.
Qi B, Wang Y, Chen ZJ, Li XN, Qi Y, Yang Y, Cui GH, Guo HZ, Li WH, Zhao S., Free PMC Article | 08/4/2018 |
| The data suggest that Med19 expression correlates with aggressive characteristics of bladder cancer, and Med19 knockdown suppresses the proliferation and migration of cancer cells through down-regulating the Wnt/beta-catenin pathway. | Knockdown of mediator subunit Med19 suppresses bladder cancer cell proliferation and migration by downregulating Wnt/β-catenin signalling pathway.
Yuan H, Yu S, Cui Y, Men C, Yang D, Gao Z, Zhu Z, Wu J., Free PMC Article | 07/14/2018 |
| The findings of this study have shown that molecular mechanisms, including aberrant activation of the WNT2 gene signaling pathway, may be involved in the pathogenesis of preeclampsia. | Promoter Methylation Status of WNT2 in Placenta from Patients with Preeclampsia.
Liu Y, Ma Y., Free PMC Article | 07/7/2018 |
| SNPs in WNT2 and FOXP2 are associated with clinical symptom severity of autism spectrum disorders. | The central nervous system patterning gene variants associated with clinical symptom severity of autism spectrum disorders.
Chien YL, Wu YY, Chen HI, Tsai WC, Chiu YN, Liu SK, Gau SS. | 06/9/2018 |
| WNT2 insufficiency might cause impaired trophoblast cell proliferation and migration via downregulation of Wnt/beta-catenin signaling pathway. | Decreased expression of WNT2 in villi of unexplained recurrent spontaneous abortion patients may cause trophoblast cell dysfunction via downregulated Wnt/β-catenin signaling pathway.
Li N, Li S, Wang Y, Wang J, Wang K, Liu X, Li Y, Liu J. | 04/14/2018 |
| Three-dimensional organotypic co-culture assays revealed that WNT2-mediated fibroblast motility and extracellular matrix remodeling enhanced cancer cell invasion of cell lines even harboring mutations in the adenomatous polyposis coli/beta-catenin pathway. | Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.
Kramer N, Schmöllerl J, Unger C, Nivarthi H, Rudisch A, Unterleuthner D, Scherzer M, Riedl A, Artaker M, Crncec I, Lenhardt D, Schwarz T, Prieler B, Han X, Hengstschläger M, Schüler J, Eferl R, Moriggl R, Sommergruber W, Dolznig H. | 10/28/2017 |
| Chondrogenic potential was higher and Wnt/beta-catenin signaling was more potently activated by a GSK-3beta inhibitor in the posterior than in the anterior part of the human infant sclera. | Anteroposterior Patterning of Gene Expression in the Human Infant Sclera: Chondrogenic Potential and Wnt Signaling.
Seko Y, Azuma N, Yokoi T, Kami D, Ishii R, Nishina S, Toyoda M, Shimokawa H, Umezawa A. | 10/28/2017 |
| data enforced the evidence that knockdown of c-Fos inhibited cell proliferation, migration, and invasion, and promoted the apoptosis of OS cells accompanied by altered expression of Wnt2 and Fzd9 | Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.
Wang Q, Liu H, Wang Q, Zhou F, Liu Y, Zhang Y, Ding H, Yuan M, Li F, Chen Y., Free PMC Article | 10/7/2017 |
| High WNT2 expression is associated with Cervical Carcinoma Metastasis. | WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition.
Zhou Y, Huang Y, Cao X, Xu J, Zhang L, Wang J, Huang L, Huang S, Yuan L, Jia W, Yu X, Luo R, Zheng M., Free PMC Article | 07/29/2017 |
| targeting beta-catenin with lipofection-delivered small interfering RNA oligonucleotide inhibited the proliferation and cell cycle arrest in G0/G1 phase and increased apoptosis of fibroblast cells, accompanied by downregulation of Wnt2 and cyclin D1 as well as the phosphorylation level of glycogen synthase kinase 3 beta in the keloid fibrosis | Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts.
Cai Y, Zhu S, Yang W, Pan M, Wang C, Wu W. | 07/15/2017 |
| Genetic polymorphisms in the WNT2 and CTNNB1 genes were closely associated with hepatocellular carcinoma risk and progression in a Chinese Han population | Influence of polymorphisms in the Wnt/β-catenin pathway genes on hepatocellular carcinoma risk in a Chinese Han population.
Li QM, Zhang FQ, Li YF, Xian QJ, Zhang YQ, Li P., Free PMC Article | 04/15/2017 |
| The WNT2 rs39315 G allele was associated with advanced tumor stage in hepatocellular carcinoma. | Genetic polymorphisms in the Wnt/β-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma.
Kim SS, Cho HJ, Lee HY, Park JH, Noh CK, Shin SJ, Lee KM, Yoo BM, Lee KJ, Cho SW, Cheong JY. | 02/18/2017 |
| Wnt2 complements Wnt/beta-catenin signaling in regulating colorectal cancer cell proliferation. | Wnt2 complements Wnt/β-catenin signaling in colorectal cancer.
Jung YS, Jun S, Lee SH, Sharma A, Park JI., Free PMC Article | 09/10/2016 |
| Wnt2/beta-catenin signaling was involved in stromal-epithelial cells interaction in endometriosis. | Metformin regulates stromal-epithelial cells communication via Wnt2/β-catenin signaling in endometriosis.
Zhang H, Xue J, Li M, Zhao X, Wei D, Li C. | 04/9/2016 |
| High expression of Wnt2 is associated with pancreatic cancer progression promoted by pancreatic stellate cells. | Wnt2 protein plays a role in the progression of pancreatic cancer promoted by pancreatic stellate cells.
Xu Y, Li H, Huang C, Zhao T, Zhang H, Zheng C, Ren H, Hao J. | 03/19/2016 |