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    WNT5A Wnt family member 5A [ Homo sapiens (human) ]

    Gene ID: 7474, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    WNT5A is a putative epi-driver of prostate cancer metastasis to the bone.

    WNT5A is a putative epi-driver of prostate cancer metastasis to the bone.
    Wilkinson EJ, Raspin K, Malley RC, Donovan S, Nott LM, Holloway AF, Dickinson JL., Free PMC Article

    08/21/2024
    Differential expression of WNT5A long and short isoforms in non-muscle-invasive bladder urothelial carcinoma.

    Differential expression of WNT5A long and short isoforms in non-muscle-invasive bladder urothelial carcinoma.
    Strope AM, Phillips C, Khadgi S, Jenkinson SA, Coschigano KT, Malgor R.

    07/26/2024
    Wnt5a-mediated autophagy contributes to the epithelial-mesenchymal transition of human bronchial epithelial cells during asthma.

    Wnt5a-mediated autophagy contributes to the epithelial-mesenchymal transition of human bronchial epithelial cells during asthma.
    Liu YB, Tan XH, Yang HH, Yang JT, Zhang CY, Jin L, Yang NS, Guan CX, Zhou Y, Liu SK, Xiong JB., Free PMC Article

    07/5/2024
    Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-kappaB activation.

    Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-κB activation.
    Ma J, Gan L, Chen H, Chen L, Hu Y, Luan C, Chen K, Zhang J.

    06/13/2024
    WNT5A regulates the proliferation, apoptosis and stemness of human stem Leydig cells via the beta-catenin signaling pathway.

    WNT5A regulates the proliferation, apoptosis and stemness of human stem Leydig cells via the β-catenin signaling pathway.
    Liu W, Du L, Cui Y, He C, He Z., Free PMC Article

    02/21/2024
    Exploring the role of the WNT5A rs566926 polymorphism and its interactions in non-syndromic orofacial cleft: a multicenter study in Brazil.

    Exploring the role of the WNT5A rs566926 polymorphism and its interactions in non-syndromic orofacial cleft: a multicenter study in Brazil.
    Lara LDS, Coletta RD, Assis Machado R, Querino Rocha de Oliveira L, Martelli Júnior H, de Almeida Reis SR, Scariot R, Evaristo Ricci Volpato L., Free PMC Article

    02/20/2024
    Associations of Wnt5a expression with liver injury in chronic hepatitis B virus infection.

    Associations of Wnt5a expression with liver injury in chronic hepatitis B virus infection.
    Ji XF, Zhou Q, Wang JW, Sun F, Gao S, Wang K., Free PMC Article

    01/8/2024
    WNT5A: a double-edged sword in colorectal cancer progression.

    WNT5A: a double-edged sword in colorectal cancer progression.
    Tufail M, Wu C.

    12/22/2023
    Expression of Wnt5a and ROR2, Components of the Noncanonical Wnt-Signaling Pathway, is Associated with Tumor Differentiation in Hepatocellular Carcinoma.

    Expression of Wnt5a and ROR2, Components of the Noncanonical Wnt-Signaling Pathway, is Associated with Tumor Differentiation in Hepatocellular Carcinoma.
    Wakizaka K, Kamiyama T, Kakisaka T, Orimo T, Nagatsu A, Aiyama T, Shichi S, Taketomi A., Free PMC Article

    12/16/2023
    FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.

    FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
    Liu M, Zhang G, Wang Z, Liu X, He K, Luo R, Duan Q, Bai R, Wang Y, Du W, Zheng Y, Shao Y.

    11/27/2023
    Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor.

    Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor.
    Stevenson MJ, Phanor SK, Patel U, Gisselbrecht SS, Bulyk ML, O'Brien LL., Free PMC Article

    11/22/2023
    CCNK Gene Deficiency Influences Neural Progenitor Cells Via Wnt5a Signaling in CCNK-Related Syndrome.

    CCNK Gene Deficiency Influences Neural Progenitor Cells Via Wnt5a Signaling in CCNK-Related Syndrome.
    Dai W, Wang H, Zhan Y, Li N, Li F, Wang J, Yan H, Zhang Y, Wang J, Wu L, Liu H, Fan Y, Tao Y, Mo X, Yang JJ, Sun K, Chen G, Yu Y.

    11/16/2023
    Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a.

    Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a.
    D'Cruz R, Kim YK, Mulder J, Ibeh N, Jiang N, Tian Y, Rosenblum ND.

    11/14/2023
    miR-139-3p/Wnt5A Axis Inhibits Metastasis in Hepatoblastoma.

    miR-139-3p/Wnt5A Axis Inhibits Metastasis in Hepatoblastoma.
    Wu Z, Chen S, Zuo T, Fu J, Gong J, Liu D, Wang B.

    11/13/2023
    FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC.

    FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC.
    Lu J, Yang Y, Liu X, Chen X, Song W, Liu Z., Free PMC Article

    11/7/2023
    Wnt5a-Flt1 activation contributes to preterm altered cerebral angiogenesis after prenatal inflammation.

    Wnt5a-Flt1 activation contributes to preterm altered cerebral angiogenesis after prenatal inflammation.
    Jiangxue H, Liling Y, Fang X, Shumei Y, Gengying L, Xuejun R, Yao Y, Chuan N, Jie Y, Zhuxiao R.

    10/11/2023
    CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression.

    CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression.
    Shi Y, Tian Y, Wu Y, Zhao Y.

    10/10/2023
    TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.

    TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.
    Zeng M, Wei X, He YL, Chen JX, Lin WT.

    05/19/2023
    WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.

    WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
    Coupe N, Guo L, Bridges E, Campo L, Espinosa O, Colling R, Marshall A, Nandakumar A, van Stiphout R, Buffa FM, Corrie PG, Middleton MR, Macaulay VM., Free PMC Article

    04/14/2023
    The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A.

    The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A.
    Singla A, Reuter S, Taube C, Peters M, Peters K., Free PMC Article

    03/21/2023
    [PDS5B inhibits the proliferation of A549 human lung cancer cells via downregulation of Wnt5a].

    [PDS5B inhibits the proliferation of A549 human lung cancer cells via downregulation of Wnt5a].
    Ma L, Ma T, Zhou W, Li J, Li Y, Xu H.

    02/9/2023
    WNT5A, betacatenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction.

    WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction.
    Sola IM, Karin-Kujundzic V, Paic F, Lijovic L, Glibo M, Serman N, Duic T, Skrtic A, Kuna K, Vranic S, Serman L., Free PMC Article

    12/24/2022
    Interferon-dependent SLC14A1[+] cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.

    Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
    Ma Z, Li X, Mao Y, Wei C, Huang Z, Li G, Yin J, Liang X, Liu Z.

    12/24/2022
    [Wnt5a activates JNK to promote the proliferation and autophagy of KGN human granulosa cells].

    [Wnt5a activates JNK to promote the proliferation and autophagy of KGN human granulosa cells].
    Ma Y, Xie X, Yuan X, Liu X, Xu J, Yang Y.

    11/12/2022
    Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene.

    Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene.
    Poppova L, Pavlova S, Gonzalez B, Kotaskova J, Plevova K, Dumbovic G, Janovska P, Bystry V, Panovska A, Bezdekova L, Maslejova S, Brychtova Y, Doubek M, Krzyzankova M, Borsky M, Mayer J, Bryja V, Alonso S, Pospisilova S., Free PMC Article

    11/5/2022
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