| Gollop-Wolfgang Complex Is Associated with a Monoallelic Variation in WNT11. | Gollop-Wolfgang Complex Is Associated with a Monoallelic Variation in WNT11.
Odrzywolski A, Tüysüz B, Debeer P, Souche E, Voet A, Dimitrov B, Krzesińska P, Vermeesch JR, Tylzanowski P., Free PMC Article | 02/6/2024 |
| Inhibition of Wnt11 impairs the osteogenesis and aggravates the inflammatory response of human mesenchymal stem cells under LPS-induced inflammatory condition. | Inhibition of Wnt11 impairs the osteogenesis and aggravates the inflammatory response of human mesenchymal stem cells under LPS-induced inflammatory condition.
Ding G, Mu-Guo S. | 05/4/2023 |
| Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload. | Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Zou Y, Pan L, Shen Y, Wang X, Huang C, Wang H, Jin X, Yin C, Wang Y, Jia J, Qian J, Zou Y, Gong H, Ge J., Free PMC Article | 02/5/2022 |
| Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis. | Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis.
Liu T, Gonzalez De Los Santos F, Hirsch M, Wu Z, Phan SH., Free PMC Article | 11/22/2021 |
| WNT11 is a direct target of early growth response protein 1. | WNT11 is a direct target of early growth response protein 1.
Kim J, Jung E, Ahn SS, Yeo H, Lee JY, Seo JK, Lee YH, Shin SY., Free PMC Article | 08/28/2021 |
| WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway. | WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway.
Wang J, Gong M, Zuo S, Xu J, Paul C, Li H, Liu M, Wang YG, Ashraf M, Xu M., Free PMC Article | 07/24/2021 |
| Aberrant expression of Wnt/beta-catenin signaling pathway genes in aggressive malignant gastric gastrointestinal stromal tumors. | Aberrant expression of Wnt/β-catenin signaling pathway genes in aggressive malignant gastric gastrointestinal stromal tumors.
Fujiya K, Ohshima K, Kitagawa Y, Hatakeyama K, Nagashima T, Aizawa D, Sugino T, Urakami K, Yamaguchi K, Terashima M. | 12/19/2020 |
| Investigated the role of Wnt11 in neuroendocrine (NE) differentiation, cell proliferation, and epithelial-to-mesenchymal transition in small-cell lung cancer (SCLC). Ascl1 plays an important role in regulating the Wnt signaling pathway and is one of the driver molecules of Wnt11 in SCLC. Wnt11 controlled NE differentiation, cell proliferation, and E-cadherin expression under the regulation of Ascl1 in SCLC cell lines. | Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology.
Tenjin Y, Kudoh S, Kubota S, Yamada T, Matsuo A, Sato Y, Ichimura T, Kohrogi H, Sashida G, Sakagami T, Ito T. | 07/11/2020 |
| that ABHD11-AS1 promotes CRC progression through the miR-1254-WNT11 pathway | Long noncoding RNA ABHD11-AS1 promote cells proliferation and invasion of colorectal cancer via regulating the miR-1254-WNT11 pathway.
He D, Yue Z, Liu L, Fang X, Chen L, Han H. | 05/16/2020 |
| WNT11 mRNA was present in three different human pancreatic ductal adenocarcinoma (PDAC) cell lines. WNT11 loss affected epithelial-mesenchymal transition, expression of neuronal and stemness biomarkers associated with metastasis. Human biopsies of PDAC showed significantly higher WNT11 mRNA levels compared with matched adjacent tissues. Upregulation of WNT11 expression ultimately worsens patient survival. | Wnt-11 Expression Promotes Invasiveness and Correlates with Survival in Human Pancreatic Ductal Adeno Carcinoma.
Dart DA, Arisan DE, Owen S, Hao C, Jiang WG, Uysal-Onganer P., Free PMC Article | 05/9/2020 |
| Genetic variants in WNT3A and WNT11 were associated with the left-right asymmetry in the amount of palatal rugae. | Left-right asymmetry in palatal rugae is associated with genetic variants in WNT signaling pathway.
Silva-Sousa AC, Marañón-Vásquez GA, Gerber JT, Judachesci CS, Stuani MBS, Nakane Matsumoto MA, Coletta RD, Scariot R, Küchler EC. | 02/8/2020 |
| Data indicate that Wnt family member 11 protein (Wnt11) is a mediator of osteoblast commitment of mesenchymal stem cells (MSCs), and increases in a surface-roughness dependent manner. | Role of Wnt11 during Osteogenic Differentiation of Human Mesenchymal Stem Cells on Microstructured Titanium Surfaces.
Boyan BD, Olivares-Navarrete R, Berger MB, Hyzy SL, Schwartz Z., Free PMC Article | 10/26/2019 |
| Downregulation of WNT11 results in fibrotic changes of bladder epithelial cells and is associated with the pathogenesis and differential diagnosis of non-Hunner-type interstitial cystitis. | Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion.
Choi D, Han JY, Shin JH, Ryu CM, Yu HY, Kim A, Lee S, Lim J, Shin DM, Choo MS., Free PMC Article | 10/12/2019 |
| Wnt11 impedes Multicellular tumor spheroid-like structures attachment to Extracellular matrix components and therefore can affect ovarian cancer progression. | Wnt11 alters integrin and cadherin expression by ovarian cancer spheroids and inhibits tumorigenesis and metastasis.
Azimian-Zavareh V, Hossein G, Ebrahimi M, Dehghani-Ghobadi Z. | 06/1/2019 |
| The study uncovers a critical role of Wnt11-mediated non-canonical Wnt signaling (CaMKII and JNK pathways) in secreted AGR2's promoted migration of CRC cells. | Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling.
Tian S, Hu J, Tao K, Wang J, Chu Y, Li J, Liu Z, Ding X, Xu L, Li Q, Cai M, Gao J, Shuai X, Wang G, Wang L, Wang Z. | 01/12/2019 |
| FZD8 co-localizes and co-immunoprecipitates with Wnt-11 and potentiates Wnt-11 activation of ATF2-dependent transcription | Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.
Murillo-Garzón V, Gorroño-Etxebarria I, Åkerfelt M, Puustinen MC, Sistonen L, Nees M, Carton J, Waxman J, Kypta RM., Free PMC Article | 12/22/2018 |
| we found that the hypoxic environment of the perivenular zone promotes Wnt11 expression in hepatocytes, which then regulates unique gene expression via activation of the non-canonical Wnt pathway | Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways.
McEnerney L, Duncan K, Bang BR, Elmasry S, Li M, Miki T, Ramakrishnan SK, Shah YM, Saito T., Free PMC Article | 07/21/2018 |
| Noncanonical Wnt signaling via Wnt5a/5b/11 may have role in the pathogenesis of aortic valve calcification. | Role of Noncanonical Wnt Signaling Pathway in Human Aortic Valve Calcification.
Albanese I, Yu B, Al-Kindi H, Barratt B, Ott L, Al-Refai M, de Varennes B, Shum-Tim D, Cerruti M, Gourgas O, Rhéaume E, Tardif JC, Schwertani A. | 06/24/2017 |
| TGF-beta1-induced sm-alpha-actin expression is mediated by WNT-11 via RhoA activation and subsequent actin cytoskeletal remodeling. | Cooperative signaling by TGF-β1 and WNT-11 drives sm-α-actin expression in smooth muscle via Rho kinase-actin-MRTF-A signaling.
Kumawat K, Koopmans T, Menzen MH, Prins A, Smit M, Halayko AJ, Gosens R. | 06/3/2017 |
| The positive rates of Wnt11 protein in normal esophageal epithelium tissue was 29.8% and in esophageal carcinomas tissue was 31.9%; there was no significant difference between the two groups | Expression of Wnt11 and Rock2 in esophageal squamous cell carcinoma by activation of the WNT/PCP pathway and its clinical significance.
Wang X, Liu D, Zhou K, Wang B, Liu Q, Deng F, Li Q, Ma Y. | 03/25/2017 |
| Data suggest that Wnt-11 may serve as a target for cervical cancer therapy. | Wnt-11 overexpression promoting the invasion of cervical cancer cells.
Wei H, Wang N, Zhang Y, Wang S, Pang X, Zhang S. | 02/18/2017 |
| The Wnt11 gene plays an important role in human mesenchymal stromal cells for enhancing the osteogenesis in an infectious environment. | Wnt11 plays an important role in the osteogenesis of human mesenchymal stem cells in a PHA/FN/ALG composite scaffold: possible treatment for infected bone defect.
Wang H, He XQ, Jin T, Li Y, Fan XY, Wang Y, Xu YQ., Free PMC Article | 10/22/2016 |
| Demonstrate immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. | Immunohistochemical Expression and Clinical Significance of Wnt11 and BCL2A1 in Complete Moles.
Hao Z, Lü W, Cheng X, Zhou C. | 08/13/2016 |
| Report high expression of Wnt11 in esophageal squamous cell carcinoma, which was significantly associated with AJCC stage. | Expression of Wnt11 and Rock2 protein with clinical characteristics of esophageal squamous cell carcinoma in Kazakh and Han patients.
Liu D, Zhou K, Li Q, Deng F, Ma Y., Free PMC Article | 05/21/2016 |
| Notch1-induced WISP-1 expression appeared to be Wnt11-dependent, but Wnt1-independent | Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1.
Liu ZJ, Li Y, Tan Y, Xiao M, Zhang J, Radtke F, Velazquez OC., Free PMC Article | 02/14/2015 |