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    XIST X inactive specific transcript [ Homo sapiens (human) ]

    Gene ID: 7503, updated on 15-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression.

    XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression.
    Wang K, Bhattacharya A, Haratake N, Daimon T, Nakashoji A, Ozawa H, Peng B, Li W, Kufe D., Free PMC Article

    07/11/2024
    lncRNA XIST Interacts with Regulatory T Cells within the Tumor Microenvironment in Chronic Hepatitis B-Associated Hepatocellular Carcinoma.

    lncRNA XIST Interacts with Regulatory T Cells within the Tumor Microenvironment in Chronic Hepatitis B-Associated Hepatocellular Carcinoma.
    Pehlivanoglu B, Aysal A, Agalar C, Egeli T, Ozbilgin M, Unek T, Unek IT, Oztop I, Aktas S, Sagol O., Free PMC Article

    06/13/2024
    Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box-Binding Homeobox 1 Pathway.

    Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box-Binding Homeobox 1 Pathway.
    Guo B, He M, Ma M, Tian Z, Jin J, Tian G., Free PMC Article

    04/30/2024
    Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data.

    Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data.
    Berenji E, Valipour Motlagh A, Fathi M, Esmaeili M, Izadi T, Rezvanian P, Zanjirband M, Safaeinejad Z, Nasr-Esfahani MH., Free PMC Article

    03/19/2024
    Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism.

    Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism.
    Wang J, Yang Y, Xu Y, Xu Z, Zhao X, Jia R, Dai Y.

    03/1/2024
    Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA.

    Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA.
    Button AC, Hall SD, Ashley EL, McHugh CA., Free PMC Article

    02/22/2024
    Exploring the XIST axis as oxidative stress-related signatures in systemic lupus erythematosus.

    Exploring the XIST axis as oxidative stress-related signatures in systemic lupus erythematosus.
    Chen Z, Dai Y, Lai Y, Gao F, Wu Y.

    02/7/2024
    METTL14-mediated lncRNA XIST silencing alleviates GDM progression by facilitating trophoblast cell proliferation and migration via the miR-497-5p/FOXO1 axis.

    METTL14-mediated lncRNA XIST silencing alleviates GDM progression by facilitating trophoblast cell proliferation and migration via the miR-497-5p/FOXO1 axis.
    Li Y, Liu Y, Yao X, Wang H, Shi Z, He M.

    02/6/2024
    Long noncoding RNA X-inactive specific transcript (lncRNA XIST) inhibits hepatic insulin resistance by competitively binding microRNA-182-5p.

    Long noncoding RNA X-inactive specific transcript (lncRNA XIST) inhibits hepatic insulin resistance by competitively binding microRNA-182-5p.
    Zhong G, Yang Q, Wang Y, Liang Y, Wang X, Zhao D., Free PMC Article

    01/31/2024
    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells.

    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells.
    Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, Ding F, Plath K.,

    01/16/2024
    Gender dimorphism in hepatocarcinogenesis-DNA methylation modification regulated X-chromosome inactivation escape molecule XIST.

    Gender dimorphism in hepatocarcinogenesis-DNA methylation modification regulated X-chromosome inactivation escape molecule XIST.
    Dai Z, Wang S, Guo X, Wang Y, Yin H, Tan J, Mu C, Sun SH, Liu H, Yang F., Free PMC Article

    01/4/2024
    Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription.

    Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription.
    Xu K, Li YD, Ren LY, Song HL, Yang QY, Xu DL.

    11/20/2023
    The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE.

    The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE.
    Crawford JD, Wang H, Trejo-Zambrano D, Cimbro R, Talbot CC Jr, Thomas MA, Curran AM, Girgis AA, Schroeder JT, Fava A, Goldman DW, Petri M, Rosen A, Antiochos B, Darrah E., Free PMC Article

    11/16/2023
    Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders.

    Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders.
    Guo RY, Song S, Wang JQ, Guo JY, Liu J, Jia Z, Yuan CC, Li B.

    11/8/2023
    Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome.

    Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome.
    Zhao LY, Li P, Yao CC, Tian RH, Tang YX, Chen YZ, Zhou Z, Li Z., Free PMC Article

    11/8/2023
    Association of XIST/miRNA155/Gab2/TAK1 cascade with the pathogenesis of anti-phospholipid syndrome and its effect on cell adhesion molecules and inflammatory mediators.

    Association of XIST/miRNA155/Gab2/TAK1 cascade with the pathogenesis of anti-phospholipid syndrome and its effect on cell adhesion molecules and inflammatory mediators.
    Abd-Elmawla MA, Elsabagh YA, Aborehab NM., Free PMC Article

    11/7/2023
    LncRNA XIST Exacerbates Oxygen-Glucose Deprivation/Reoxygenation-Induced Cerebral Injury Through the miR-25-3p/TRAF3 Axis.

    LncRNA XIST Exacerbates Oxygen-Glucose Deprivation/Reoxygenation-Induced Cerebral Injury Through the miR-25-3p/TRAF3 Axis.
    Li Y, Zhang JK, Yu ZT, Jiang JW, Tang H, Tu GL, Xia Y.

    09/7/2023
    Silencing of long noncoding RNA X-inactive specific transcript alleviates Abeta1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization.

    Silencing of long noncoding RNA X-inactive specific transcript alleviates Aβ1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization.
    Zhao KP, Wang XY, Shao MQ, He CY, Yuan FQ., Free PMC Article

    09/6/2023
    LncRNA XIST facilitates hypertrophy of ligamentum flavum by activating VEGFA-mediated autophagy through sponging miR-302b-3p.

    LncRNA XIST facilitates hypertrophy of ligamentum flavum by activating VEGFA-mediated autophagy through sponging miR-302b-3p.
    Cao Y, Li J, Qiu S, Ni S, Duan Y., Free PMC Article

    05/26/2023
    Long non-coding RNA XIST promotes the malignant features of oral squamous cell carcinoma (OSCC) cells through regulating miR-133a-5p/VEGFB.

    Long non-coding RNA XIST promotes the malignant features of oral squamous cell carcinoma (OSCC) cells through regulating miR-133a-5p/VEGFB.
    Wu K, Wu W, Wu M, Liu W.

    01/28/2023
    LncRNA RNA XIST binding to GATA1 contributes to rheumatoid arthritis through its effects on proliferation of synovial fibroblasts and angiogenesis via regulation of CCN6.

    LncRNA RNA XIST binding to GATA1 contributes to rheumatoid arthritis through its effects on proliferation of synovial fibroblasts and angiogenesis via regulation of CCN6.
    Yu B, Chen Y, Chen E, Zuo F, Yuan Y, Zhao X, Xiao C.

    01/28/2023
    Sinomenine Suppressed Keratinocyte Proliferation and Imiquimod-Induced Psoriasis-Like Dermatitis by Regulating lncRNA XIST.

    Sinomenine Suppressed Keratinocyte Proliferation and Imiquimod-Induced Psoriasis-Like Dermatitis by Regulating lncRNA XIST.
    Xiang S, Wu X, Xiang Y.

    01/11/2023
    Regulation of long non-coding RNAs XIST and ROR induced by homeodomain protein TGIF2LX in colorectal cancer.

    Regulation of long non-coding RNAs XIST and ROR induced by homeodomain protein TGIF2LX in colorectal cancer.
    Tabarestani FO, Akbari A, Karizi SZ, Sotoodehnejadnematalahi F.

    12/24/2022
    Long non-coding RNA XIST negatively regulates thoracic aortic aneurysm cell proliferation by targeting the miR-193a-5p/KLF7 axis.

    Long non-coding RNA XIST negatively regulates thoracic aortic aneurysm cell proliferation by targeting the miR-193a-5p/KLF7 axis.
    Zhu M, Tan M, Xu F, Huang Y, Yang J.

    12/17/2022
    Knockdown of lncRNA XIST Ameliorates IL-1beta-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-kappaB Signaling Pathway.

    Knockdown of lncRNA XIST Ameliorates IL-1β-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-κB Signaling Pathway.
    Cao G, Zhou H, Wang D, Xu L., Free PMC Article

    12/17/2022
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