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    XPC XPC complex subunit, DNA damage recognition and repair factor [ Homo sapiens (human) ]

    Gene ID: 7508, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Relationship between ERCC1 and XPC polymorphisms and the susceptibility to head and neck carcinoma: A systematic review, meta-analysis, and trial sequential analysis.

    Relationship between ERCC1 and XPC polymorphisms and the susceptibility to head and neck carcinoma: A systematic review, meta-analysis, and trial sequential analysis.
    Imani MM, Akbari S, Shalchi M, Sadeghi E, Sadeghi M.

    04/26/2024
    Genetic Polymorphisms of XPC, XPD, XPG Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients: A Hospital Based Study from Maharashtra.

    Genetic Polymorphisms of XPC, XPD, XPG Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients: A Hospital Based Study from Maharashtra.
    Gudur AK, Kale SR, Gudur RA, Bhosale SJ, Datkhile KD., Free PMC Article

    02/16/2024
    Structural modeling and analyses of genetic variations in the human XPC nucleotide excision repair protein.

    Structural modeling and analyses of genetic variations in the human XPC nucleotide excision repair protein.
    Le J, Min JH., Free PMC Article

    12/20/2023
    A Significant Increasing Risk Association between Cigarette Smoking and XPA and XPC Genes Polymorphisms.

    A Significant Increasing Risk Association between Cigarette Smoking and XPA and XPC Genes Polymorphisms.
    Almushawwah S, Almutairi MH, Alamri AM, Semlali A., Free PMC Article

    09/8/2023
    Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.

    Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
    Kim J, Li CL, Chen X, Cui Y, Golebiowski FM, Wang H, Hanaoka F, Sugasawa K, Yang W., Free PMC Article

    05/17/2023
    Regulation of XPC Binding Dynamics and Global Nucleotide Excision Repair by p63 and Vitamin D Receptor.

    Regulation of XPC Binding Dynamics and Global Nucleotide Excision Repair by p63 and Vitamin D Receptor.
    Wong CT, Ona K, Oh DH.

    03/22/2023
    Joint effects of polycyclic aromatic hydrocarbons, smoking, and XPC polymorphisms on damage in exon 2 of KRAS gene among young coke oven workers.

    Joint effects of polycyclic aromatic hydrocarbons, smoking, and XPC polymorphisms on damage in exon 2 of KRAS gene among young coke oven workers.
    Chen S, Yin X, He Y, He Q, Li X, Yan M, Huang S, Lu J, Yang B., Free PMC Article

    08/27/2022
    Loss of Function Variants in the XPC Causes Severe Xeroderma Pigmentosum in Three Large Consanguineous Families.", trans "Loss-of-Function-Varianten im XPC als Ursache schwerer Xeroderma pigmentosum in drei grossen konsanguinen Familien.

    Loss of Function Variants in the XPC Causes Severe Xeroderma Pigmentosum in Three Large Consanguineous Families.
    Nawal W, Ullah A, Ullah U, Farrakh K, Ahmad F, Khan H, Ahmad GS, Khan B, Ansar M, Kalsoom UE, Ahmad W.

    05/28/2022
    Association of DNA repair gene XPC Ala499Val (rs2228000 C>T) and Lys939Gln (rs2228001 A>C) polymorphisms with the risk of chronic myeloid leukemia: A case-control study in a South Indian population.

    Association of DNA repair gene XPC Ala499Val (rs2228000 C>T) and Lys939Gln (rs2228001 A>C) polymorphisms with the risk of chronic myeloid leukemia: A case-control study in a South Indian population.
    Lakkireddy S, Aula S, Kapley A, Gundeti S, Kutala VK, Jamil K.

    03/19/2022
    Hsa_circ_0069244 acts as the sponge of miR-346 to inhibit non-small cell lung cancer progression by regulating XPC expression.

    Hsa_circ_0069244 acts as the sponge of miR-346 to inhibit non-small cell lung cancer progression by regulating XPC expression.
    Shi J, Wang H, Feng W, Huang S, An J, Wang L, Jiang J.

    01/1/2022
    Increased H2O2 levels and p53 stabilization lead to mitochondrial dysfunction in XPC-deficient cells.

    Increased H2O2 levels and p53 stabilization lead to mitochondrial dysfunction in XPC-deficient cells.
    Freire TS, Mori MP, Miranda JNFA, Muta LYM, Machado FT, Moreno NC, Souza-Pinto NC.

    01/1/2022
    Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study.

    Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study.
    Wang J, Guan C, Sui J, Zang Y, Wu Y, Zhang R, Qi X, Piao S., Free PMC Article

    12/4/2021
    Genetic variations in nucleotide excision repair pathway genes and hepatoblastoma susceptibility.

    Genetic variations in nucleotide excision repair pathway genes and hepatoblastoma susceptibility.
    Zhuo Z, Miao L, Hua W, Chen H, Yang Z, Li Y, Zhang J, Li S, Cheng J, Li L, Xia H, He J.

    11/27/2021
    Vitamin D Receptor Promotes Global Nucleotide Excision Repair by Facilitating XPC Dissociation from Damaged DNA.

    Vitamin D Receptor Promotes Global Nucleotide Excision Repair by Facilitating XPC Dissociation from Damaged DNA.
    Wong CT, Oh DH.

    11/27/2021
    A33512C and Intronic Poly(AT) Insertion/Deletion (PAT-/+) Polymorphisms of the XPC Gene and Their Association With the Risk of Breast Cancer.

    A33512C and Intronic Poly(AT) Insertion/Deletion (PAT-/+) Polymorphisms of the XPC Gene and Their Association With the Risk of Breast Cancer.
    Qazvini MG, Salehi Z, Mashayekhi F, Saedi HS.

    10/16/2021
    DNA Repair Gene Polymorphisms and Susceptibility to Urothelial Carcinoma in a Southeastern European Population.

    DNA Repair Gene Polymorphisms and Susceptibility to Urothelial Carcinoma in a Southeastern European Population.
    Samara M, Papathanassiou M, Mitrakas L, Koukoulis G, Vlachostergios PJ, Tzortzis V., Free PMC Article

    10/2/2021
    HDAC3 Is Required for XPC Recruitment and Nucleotide Excision Repair of DNA Damage Induced by UV Irradiation.

    HDAC3 Is Required for XPC Recruitment and Nucleotide Excision Repair of DNA Damage Induced by UV Irradiation.
    Nishimoto K, Niida H, Uchida C, Ohhata T, Kitagawa K, Motegi A, Suda T, Kitagawa M.

    08/14/2021
    Association of XPC Polymorphisms with Cutaneous Malignant Melanoma Risk: Evidence from a Meta-Analysis.

    Association of XPC Polymorphisms with Cutaneous Malignant Melanoma Risk: Evidence from a Meta-Analysis.
    Asadian F, Niktabar SM, Ghelmani Y, Kargar S, Akbarian E, Emarati SA, Sadeghizadeh-Yazdi J, Neamatzadeh H.

    08/7/2021
    Effects of Xeroderma pigmentosum group C polymorphism on the likelihood of prostate cancer.

    Effects of Xeroderma pigmentosum group C polymorphism on the likelihood of prostate cancer.
    Yan Y, Xu J, Xu B, Wen Q, Zhou J, Zhang L, Zuo L, Lv G, Shi Y., Free PMC Article

    07/10/2021
    XPC as breast cancer susceptibility gene: evidence from genetic profiling, statistical inferences and protein structural analysis.

    XPC as breast cancer susceptibility gene: evidence from genetic profiling, statistical inferences and protein structural analysis.
    Malik SS, Zia A, Rashid S, Mubarik S, Masood N, Hussain M, Yasmin A, Bano R.

    06/26/2021
    Polymorphisms in XPC and XPD genes modulate DNA damage in pesticide-exposed agricultural workers of Punjab, North-West India.

    Polymorphisms in XPC and XPD genes modulate DNA damage in pesticide-exposed agricultural workers of Punjab, North-West India.
    Kaur K, Kaur R.

    05/1/2021
    Polymorphisms in XPC Gene and Risk of Uterine Leiomyoma in Reproductive Women.

    Polymorphisms in XPC Gene and Risk of Uterine Leiomyoma in Reproductive Women.
    Liu ZQ, Lu MY, Liu B.

    04/3/2021
    The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a missing nucleotide opposite the lesion.

    The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a missing nucleotide opposite the lesion.
    Feher KM, Kolbanovskiy A, Durandin A, Shim Y, Min JH, Lee YC, Shafirovich V, Mu H, Broyde S, Geacintov NE., Free PMC Article

    04/3/2021
    Variants in XPC, Noxa and TLR4 genes are not associated with bleomycin-induced lung injury in Hodgkin lymphoma patients.

    Variants in XPC, Noxa and TLR4 genes are not associated with bleomycin-induced lung injury in Hodgkin lymphoma patients.
    Thakkar DN, Prapath I, Adithan S, Ramasamy K, Selvarajan S, Dubashi B.

    03/27/2021
    Identification of a novel protein truncating mutation p.Asp98* in XPC associated with xeroderma pigmentosum in a consanguineous Pakistani family.

    Identification of a novel protein truncating mutation p.Asp98* in XPC associated with xeroderma pigmentosum in a consanguineous Pakistani family.
    Ali MZ, Blatterer J, Khan MA, Schaflinger E, Petek E, Ahmad S, Khan E, Windpassinger C., Free PMC Article

    03/27/2021
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