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    CEMP1 cementum protein 1 [ Homo sapiens (human) ]

    Gene ID: 752014, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cementum protein 1 gene-modified adipose-derived mesenchymal stem cell sheets enhance periodontal regeneration in osteoporosis rat.

    Cementum protein 1 gene-modified adipose-derived mesenchymal stem cell sheets enhance periodontal regeneration in osteoporosis rat.
    Wang M, He M, Xu X, Wu Z, Tao J, Yin F, Luo K, Jiang J.

    07/24/2023
    Protease-activated receptor type 1 (PAR1) increases CEMP1 gene expression through MAPK/ERK pathway.

    Protease-activated receptor type 1 (PAR1) increases CEMP1 gene expression through MAPK/ERK pathway.
    Rovai ES, Alves T, Gasparoni LM, França BN, Sipert CR, Kantarci A, Holzhausen M.

    04/30/2022
    Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/beta-catenin Signaling in Human Oral Mucosa Stem Cells.

    Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/β-catenin Signaling in Human Oral Mucosa Stem Cells.
    Arroyo R, López S, Romo E, Montoya G, Hoz L, Pedraza C, Garfias Y, Arzate H., Free PMC Article

    11/28/2020
    Cementum protein 1-derived peptide (CEMP 1-p1) modulates hydroxyapatite crystal formation in vitro.

    Cementum protein 1-derived peptide (CEMP 1-p1) modulates hydroxyapatite crystal formation in vitro.
    Montoya G, Correa R, Arenas J, Hoz L, Romo E, Arroyo R, Zeichner-David M, Arzate H.

    04/4/2020
    data demonstrate that CEMP-1-p1 is an effective bioactive peptide for bone tissue regeneration. The application of this bioactive peptide may lead to implementing new strategies for the regeneration of bone and other mineralized tissues

    Synthetic cementum protein 1-derived peptide regulates mineralization in vitro and promotes bone regeneration in vivo.
    Correa R, Arenas J, Montoya G, Hoz L, López S, Salgado F, Arroyo R, Salmeron N, Romo E, Zeichner-David M, Arzate H.

    09/21/2019
    On day 14, mineralization nodules appeared, as seen by positive von Kossa staining; the nodules increased in number and size by day 21. The expression of CEMP1 was detected on day 5, and its expression level increased gradually by day 7, reached a peak on day 14, and decreased by day 21

    Establishment of a Primary Culture System of Human Periodontal Ligament Cells that Differentiate into Cementum Protein 1-expressing Cementoblast-like Cells.
    Kadokura H, Yamazaki T, Masuda Y, Kato Y, Hasegawa A, Sakagami H, Yokose S., Free PMC Article

    06/8/2019
    The synthesis of hydroxyapatite with different crystallinities by controlling the concentration of recombinant CEMP1 for biological application.

    The synthesis of hydroxyapatite with different crystallinities by controlling the concentration of recombinant CEMP1 for biological application.
    Chen X, Liu Y, Yang J, Wu W, Miao L, Yu Y, Yang X, Sun W.

    09/10/2016
    CEMP1 exerts modulation of a number of cellular genes.

    CEMP1 Induces Transformation in Human Gingival Fibroblasts.
    Bermúdez M, Imaz-Rosshandler I, Rangel-Escareño C, Zeichner-David M, Arzate H, Mercado-Celis GE., Free PMC Article

    02/13/2016
    when HIF-1 was activated by gene introduction or chemically, CEMP1 expression and mineralization increased.

    Hypoxia promotes CEMP1 expression and induces cementoblastic differentiation of human dental stem cells in an HIF-1-dependent manner.
    Choi H, Jin H, Kim JY, Lim KT, Choung HW, Park JY, Chung JH, Choung PH., Free PMC Article

    09/6/2014
    human primary cementoblasts subjected to compression and IL-1beta stimulation impeded BSP and CEMP-1 expression, proteins that are associated with cementogenesis.

    Human primary cementoblasts respond to combined IL-1β stimulation and compression with an impaired BSP and CEMP-1 expression.
    Diercke K, König A, Kohl A, Lux CJ, Erber R.

    06/23/2012
    These data demonstrate for the first time that the CEMP1 is not only a marker protein for cementoblast-related cells, but it also regulates cementoblast commitment in periodontal ligament cells

    Cementum protein 1 (CEMP1) induces a cementoblastic phenotype and reduces osteoblastic differentiation in periodontal ligament cells.
    Komaki M, Iwasaki K, Arzate H, Narayanan AS, Izumi Y, Morita I.

    02/4/2012
    CEMP1 plays a role during the biomineralization process by promoting octacalcium phosphate crystal nucleation.

    Characterization of recombinant human cementum protein 1 (hrCEMP1): primary role in biomineralization.
    Villarreal-Ramírez E, Moreno A, Mas-Oliva J, Chávez-Pacheco JL, Narayanan AS, Gil-Chavarría I, Zeichner-David M, Arzate H.

    01/21/2010
    CEMP1 might participate in differentiation and mineralization of nonosteogenic cells, and it might have a potential function in cementum and bone formation

    Human Cementum Protein 1 induces expression of bone and cementum proteins by human gingival fibroblasts.
    Carmona-Rodríguez B, Alvarez-Pérez MA, Narayanan AS, Zeichner-David M, Reyes-Gasga J, Molina-Guarneros J, García-Hernández AL, Suárez-Franco JL, Chavarría IG, Villarreal-Ramírez E, Arzate H.

    01/21/2010
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