Cementum protein 1 gene-modified adipose-derived mesenchymal stem cell sheets enhance periodontal regeneration in osteoporosis rat. | Cementum protein 1 gene-modified adipose-derived mesenchymal stem cell sheets enhance periodontal regeneration in osteoporosis rat. Wang M, He M, Xu X, Wu Z, Tao J, Yin F, Luo K, Jiang J. | 07/24/2023 |
Protease-activated receptor type 1 (PAR1) increases CEMP1 gene expression through MAPK/ERK pathway. | Protease-activated receptor type 1 (PAR1) increases CEMP1 gene expression through MAPK/ERK pathway. Rovai ES, Alves T, Gasparoni LM, França BN, Sipert CR, Kantarci A, Holzhausen M. | 04/30/2022 |
Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/beta-catenin Signaling in Human Oral Mucosa Stem Cells. | Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/β-catenin Signaling in Human Oral Mucosa Stem Cells. Arroyo R, López S, Romo E, Montoya G, Hoz L, Pedraza C, Garfias Y, Arzate H., Free PMC Article | 11/28/2020 |
Cementum protein 1-derived peptide (CEMP 1-p1) modulates hydroxyapatite crystal formation in vitro. | Cementum protein 1-derived peptide (CEMP 1-p1) modulates hydroxyapatite crystal formation in vitro. Montoya G, Correa R, Arenas J, Hoz L, Romo E, Arroyo R, Zeichner-David M, Arzate H. | 04/4/2020 |
data demonstrate that CEMP-1-p1 is an effective bioactive peptide for bone tissue regeneration. The application of this bioactive peptide may lead to implementing new strategies for the regeneration of bone and other mineralized tissues | Synthetic cementum protein 1-derived peptide regulates mineralization in vitro and promotes bone regeneration in vivo. Correa R, Arenas J, Montoya G, Hoz L, López S, Salgado F, Arroyo R, Salmeron N, Romo E, Zeichner-David M, Arzate H. | 09/21/2019 |
On day 14, mineralization nodules appeared, as seen by positive von Kossa staining; the nodules increased in number and size by day 21. The expression of CEMP1 was detected on day 5, and its expression level increased gradually by day 7, reached a peak on day 14, and decreased by day 21 | Establishment of a Primary Culture System of Human Periodontal Ligament Cells that Differentiate into Cementum Protein 1-expressing Cementoblast-like Cells. Kadokura H, Yamazaki T, Masuda Y, Kato Y, Hasegawa A, Sakagami H, Yokose S., Free PMC Article | 06/8/2019 |
The synthesis of hydroxyapatite with different crystallinities by controlling the concentration of recombinant CEMP1 for biological application. | The synthesis of hydroxyapatite with different crystallinities by controlling the concentration of recombinant CEMP1 for biological application. Chen X, Liu Y, Yang J, Wu W, Miao L, Yu Y, Yang X, Sun W. | 09/10/2016 |
CEMP1 exerts modulation of a number of cellular genes. | CEMP1 Induces Transformation in Human Gingival Fibroblasts. Bermúdez M, Imaz-Rosshandler I, Rangel-Escareño C, Zeichner-David M, Arzate H, Mercado-Celis GE., Free PMC Article | 02/13/2016 |
when HIF-1 was activated by gene introduction or chemically, CEMP1 expression and mineralization increased. | Hypoxia promotes CEMP1 expression and induces cementoblastic differentiation of human dental stem cells in an HIF-1-dependent manner. Choi H, Jin H, Kim JY, Lim KT, Choung HW, Park JY, Chung JH, Choung PH., Free PMC Article | 09/6/2014 |
human primary cementoblasts subjected to compression and IL-1beta stimulation impeded BSP and CEMP-1 expression, proteins that are associated with cementogenesis. | Human primary cementoblasts respond to combined IL-1β stimulation and compression with an impaired BSP and CEMP-1 expression. Diercke K, König A, Kohl A, Lux CJ, Erber R. | 06/23/2012 |
These data demonstrate for the first time that the CEMP1 is not only a marker protein for cementoblast-related cells, but it also regulates cementoblast commitment in periodontal ligament cells | Cementum protein 1 (CEMP1) induces a cementoblastic phenotype and reduces osteoblastic differentiation in periodontal ligament cells. Komaki M, Iwasaki K, Arzate H, Narayanan AS, Izumi Y, Morita I. | 02/4/2012 |
CEMP1 plays a role during the biomineralization process by promoting octacalcium phosphate crystal nucleation. | Characterization of recombinant human cementum protein 1 (hrCEMP1): primary role in biomineralization. Villarreal-Ramírez E, Moreno A, Mas-Oliva J, Chávez-Pacheco JL, Narayanan AS, Gil-Chavarría I, Zeichner-David M, Arzate H. | 01/21/2010 |
CEMP1 might participate in differentiation and mineralization of nonosteogenic cells, and it might have a potential function in cementum and bone formation | Human Cementum Protein 1 induces expression of bone and cementum proteins by human gingival fibroblasts. Carmona-Rodríguez B, Alvarez-Pérez MA, Narayanan AS, Zeichner-David M, Reyes-Gasga J, Molina-Guarneros J, García-Hernández AL, Suárez-Franco JL, Chavarría IG, Villarreal-Ramírez E, Arzate H. | 01/21/2010 |