| Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine. | Structural basis for human Ca(v)1.2 inhibition by multiple drugs and the neurotoxin calciseptine.
Gao S, Yao X, Chen J, Huang G, Fan X, Xue L, Li Z, Wu T, Zheng Y, Huang J, Jin X, Wang Y, Wang Z, Yu Y, Liu L, Pan X, Song C, Yan N. | 11/27/2023 |
| Effect of rs1108580 of DBH and rs1006737 of CACNA1C on Cognition and Tardive Dyskinesia in a North Indian Schizophrenia Cohort. | Effect of rs1108580 of DBH and rs1006737 of CACNA1C on Cognition and Tardive Dyskinesia in a North Indian Schizophrenia Cohort.
Punchaichira TJ, Kukshal P, Bhatia T, Deshpande SN, Thelma BK. | 11/22/2023 |
| The rs216009 single-nucleotide polymorphism of the CACNA1C gene is associated with phantom tooth pain. | The rs216009 single-nucleotide polymorphism of the CACNA1C gene is associated with phantom tooth pain.
Morii M, Ohka S, Nishizawa D, Hasegawa J, Nakayama K, Ebata Y, Soeda M, Fukuda KI, Yoshida K, Koshika K, Ichinohe T, Ikeda K., Free PMC Article | 11/3/2023 |
| A novel risk variant block across introns 36-45 of CACNA1C for schizophrenia: a cohort-wise replication and cerebral region-wide validation study. | A novel risk variant block across introns 36-45 of CACNA1C for schizophrenia: a cohort-wise replication and cerebral region-wide validation study.
Guo X, Wang S, Lin X, Wang Z, Dou Y, Cao Y, Zhang Y, Luo X, Kang L, Yu T, Wang Z, Tan Y, Gao S, Zheng H, Zhao F, Wang H, Wang K, Xie F, Chen W, Luo X., | 09/19/2023 |
| CACNA1C-Related Channelopathies. | CACNA1C-Related Channelopathies.
Herold KG, Hussey JW, Dick IE., Free PMC Article | 08/2/2023 |
| EMC chaperone-CaV structure reveals an ion channel assembly intermediate. | EMC chaperone-Ca(V) structure reveals an ion channel assembly intermediate.
Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL Jr., Free PMC Article | 07/26/2023 |
| Phenotypic Characterization of Timothy Syndrome Caused by the CACNA1C p.Gly402Ser Variant. | Phenotypic Characterization of Timothy Syndrome Caused by the CACNA1C p.Gly402Ser Variant.
Delinière A, Haddad C, Herrera-Siklódy C, Hermida A, Pruvot E, Bressieux-Degueldre S, Millat G, Janin A, Hermida JS, Asatryan B, Chevalier P. | 06/23/2023 |
| Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis. | Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.
Novaes de Oliveira Roldan AC, Fernandes Júnior LCC, de Oliveira CEC, Nunes SOV. | 03/13/2023 |
| BDNF Levels According to Variations in the CACNA1C Gene: Sex-Based Disparity. | BDNF Levels According to Variations in the CACNA1C Gene: Sex-Based Disparity.
Bastos CR, Xavier J, Camerini L, Dewes SS, Moreira FP, Wiener CD, Jansen K, Kaster MP, de Mattos Souza LD, da Silva RA, Oses JP, Portela LV, Lara DR, Tovo-Rodrigues L, Ghisleni G. | 01/14/2023 |
| A CACNA1C variant associated with cardiac arrhythmias provides mechanistic insights in the calmodulation of L-type Ca[2+] channels. | A CACNA1C variant associated with cardiac arrhythmias provides mechanistic insights in the calmodulation of L-type Ca(2+) channels.
Zhao J, Segura E, Marsolais M, Parent L., Free PMC Article | 01/11/2023 |
| A Cross-Sectional Study of the Neuropsychiatric Phenotype of CACNA1C-Related Disorder. | A Cross-Sectional Study of the Neuropsychiatric Phenotype of CACNA1C-Related Disorder.
Levy RJ, Timothy KW, Underwood JFG, Hall J, Bernstein JA, Pașca SP. | 01/7/2023 |
| Analysis of CACNA1C and KCNH2 Risk Variants on Cardiac Autonomic Function in Patients with Schizophrenia. | Analysis of CACNA1C and KCNH2 Risk Variants on Cardiac Autonomic Function in Patients with Schizophrenia.
Refisch A, Komatsuzaki S, Ungelenk M, Schumann A, Chung HY, Schilling SS, Jantzen W, Schröder S, Nöthen MM, Mühleisen TW, Hübner CA, Bär KJ., Free PMC Article | 12/3/2022 |
| Inhibition of L-type voltage-gated calcium channel-mediated Ca(2+) influx suppresses the collective migration and invasion of ameloblastoma. | Inhibition of L-type voltage-gated calcium channel-mediated Ca(2+) influx suppresses the collective migration and invasion of ameloblastoma.
Li S, Kim HY, Lee DJ, Park SH, Otsu K, Harada H, Jung YS, Jung HS., Free PMC Article | 11/12/2022 |
| CACNA1C (CaV1.2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics and pharmacoepidemiology. | CACNA1C (Ca(V)1.2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics and pharmacoepidemiology.
Harrison PJ, Husain SM, Lee H, Los Angeles A, Colbourne L, Mould A, Hall NAL, Haerty W, Tunbridge EM. | 10/22/2022 |
| Genetic Polymorphisms in miR-137 and Its Target Genes, TCF4 and CACNA1C, Contribute to the Risk of Bipolar Disorder: A Preliminary Case-Control Study and Bioinformatics Analysis. | Genetic Polymorphisms in miR-137 and Its Target Genes, TCF4 and CACNA1C, Contribute to the Risk of Bipolar Disorder: A Preliminary Case-Control Study and Bioinformatics Analysis.
Mokhtari MA, Sargazi S, Saravani R, Heidari Nia M, Mirinejad S, Hadzsiev K, Bene J, Shakiba M., Free PMC Article | 10/15/2022 |
| A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A). | A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A).
Guardiola-Ripoll M, Almodóvar-Payá C, Lubeiro A, Sotero A, Salvador R, Fuentes-Claramonte P, Salgado-Pineda P, Papiol S, Ortiz-Gil J, Gomar JJ, Guerrero-Pedraza A, Sarró S, Maristany T, Molina V, Pomarol-Clotet E, Fatjó-Vilas M. | 10/8/2022 |
| Further evidence and meta-analysis support association of a single nucleotide polymorphism rs4765905 in CACNA1C with schizophrenia. | Further evidence and meta-analysis support association of a single nucleotide polymorphism rs4765905 in CACNA1C with schizophrenia.
Wang Z, Fu Y, Jiang F, Chen L, Chen W, Guo X, Luo X. | 08/27/2022 |
| Novel CACNA1C R511Q mutation, located in domain - linker, causes non-syndromic type-8 long QT syndrome. | Novel CACNA1C R511Q mutation, located in domain Ⅰ-Ⅱ linker, causes non-syndromic type-8 long QT syndrome.
Nakajima T, Kawabata-Iwakawa R, Tamura S, Hasegawa H, Kobari T, Itoh H, Horie M, Nishiyama M, Kurabayashi M, Kaneko Y, Ishii H., Free PMC Article | 07/30/2022 |
| Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder. | Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder.
Scotti-Muzzi E, Chile T, Vallada H, Otaduy MCG, Soeiro-de-Souza MG. | 06/18/2022 |
| Role of CACNA1C in Brugada syndrome: Prevalence and phenotype of probands referred for genetic testing. | Role of CACNA1C in Brugada syndrome: Prevalence and phenotype of probands referred for genetic testing.
Novelli V, Memmi M, Malovini A, Mazzanti A, Liu N, Yanfei R, Bongianino R, Denegri M, Monteforte N, Bloise R, Morini M, Napolitano C. | 05/7/2022 |
| An independent, replicable, functional and significant risk variant block at intron 3 of CACNA1C for schizophrenia. | An independent, replicable, functional and significant risk variant block at intron 3 of CACNA1C for schizophrenia.
Wang Z, Chen W, Cao Y, Dou Y, Fu Y, Zhang Y, Luo X, Kang L, Liu N, Shi YS, Li CR, Xu Y, Guo X, Luo X. | 04/30/2022 |
| Increased Ca2+ influx through CaV1.2 drives aortic valve calcification. | Increased Ca2+ influx through CaV1.2 drives aortic valve calcification.
Matsui M, Bouchareb R, Storto M, Hussain Y, Gregg A, Marx SO, Pitt GS., Free PMC Article | 04/16/2022 |
| Disrupted Cacna1c gene expression perturbs spontaneous Ca(2+) activity causing abnormal brain development and increased anxiety. | Disrupted Cacna1c gene expression perturbs spontaneous Ca(2+) activity causing abnormal brain development and increased anxiety.
Smedler E, Louhivuori L, Romanov RA, Masini D, Dehnisch Ellström I, Wang C, Caramia M, West Z, Zhang S, Rebellato P, Malmersjö S, Brusini I, Kanatani S, Fisone G, Harkany T, Uhlén P., Free PMC Article | 03/12/2022 |
| Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events. | Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events.
Ballouz S, Mangala MM, Perry MD, Heitmann S, Gillis JA, Hill AP, Vandenberg JI., Free PMC Article | 02/26/2022 |
| Expanding the phenotype of CACNA1C mutation disorders. | Expanding the phenotype of CACNA1C mutation disorders.
Gakenheimer-Smith L, Meyers L, Lundahl D, Menon SC, Bunch TJ, Sawyer BL, Tristani-Firouzi M, Etheridge SP., Free PMC Article | 02/5/2022 |