| Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma. | Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest F, Noerenberg D, Hennch C, Yoshida K, Hablesreiter R, Nimo J, Sasca D, Kirchner M, Mansouri L, Inoue Y, Wiegand L, Staiger AM, Casadei B, Korkolopoulou P, Weiner J, Lopez-Guillermo A, Warth A, Schneider T, Nagy Á, Klapper W, Hummel M, Kanellis G, Anagnostopoulos I, Mertins P, Bullinger L, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F., Free PMC Article | 11/10/2023 |
| FTO-stabilized miR-139-5p targets ZNF217 to suppress prostate cancer cell malignancies by inactivating the PI3K/Akt/mTOR signal pathway. | FTO-stabilized miR-139-5p targets ZNF217 to suppress prostate cancer cell malignancies by inactivating the PI3K/Akt/mTOR signal pathway.
Azhati B, Reheman A, Dilixiati D, Rexiati M. | 05/20/2023 |
| Hsa_circ_0069094 positively regulates the expression of oncogenic ZNF217 by competitively targeting miR-758-3p to promote the development of breast cancer. | Hsa_circ_0069094 positively regulates the expression of oncogenic ZNF217 by competitively targeting miR-758-3p to promote the development of breast cancer.
Ou H, Li J, Lv Q, Feng D. | 12/3/2022 |
| MicroRNA-135 inhibits initiation of epithelial-mesenchymal transition in breast cancer by targeting ZNF217 and promoting m6A modification of NANOG. | MicroRNA-135 inhibits initiation of epithelial-mesenchymal transition in breast cancer by targeting ZNF217 and promoting m6A modification of NANOG.
Xu LM, Zhang J, Ma Y, Yuan YJ, Yu H, Wang J, Cao XC, Zhu L, Wang P. | 05/14/2022 |
| Interferon regulatory factor 5induced upregulation of zincfinger protein 217 promotes pancreatic carcinoma progression. | Interferon regulatory factor 5‑induced upregulation of zinc‑finger protein 217 promotes pancreatic carcinoma progression.
Qiao X, Lv S, Qiao Y, Wang F, Miao L., Free PMC Article | 04/16/2022 |
| lncRNA SNHG1 Knockdown Alleviates Amyloid-beta-Induced Neuronal Injury by Regulating ZNF217 via Sponging miR-361-3p in Alzheimer's Disease. | lncRNA SNHG1 Knockdown Alleviates Amyloid-β-Induced Neuronal Injury by Regulating ZNF217 via Sponging miR-361-3p in Alzheimer's Disease.
Gao Y, Zhang N, Lv C, Li N, Li X, Li W. | 09/11/2021 |
| Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma. | Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma.
Smeester BA, Draper GM, Slipek NJ, Larsson AT, Stratton N, Pomeroy EJ, Becklin KL, Yamamoto K, Williams KB, Laoharawee K, Peterson JJ, Abrahante JE, Rathe SK, Mills LJ, Crosby MR, Hudson WA, Rahrmann EP, Largaespada DA, Moriarity BS., Free PMC Article | 08/14/2021 |
| Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. | Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM., Free PMC Article | 02/20/2021 |
| Indicated ZNF217 could recruit LSD1 to affect CDH1 epigenetic expression from transcription level. | The coordination between ZNF217 and LSD1 contributes to hepatocellular carcinoma progress and is negatively regulated by miR-101.
Si W, Zhao Y, Zhou J, Zhang Q, Zhang Y. | 05/30/2020 |
| ZNF217 inhibited both COX2 and PGE2 synthesis through estradiol in KGN cells. ZNF217 and aromatase were decreased, whereas COX2 and PGE2 were increased in the GC of women with PCOS | A candidate pathogenic gene, zinc finger gene 217 (ZNF217), may contribute to polycystic ovary syndrome through prostaglandin E2.
Zhai J, Li S, Cheng X, Chen ZJ, Li W, Du Y. | 05/2/2020 |
| ZNF217 contributed to ovarian hyperstimulation syndrome (OHSS) onset through promoting E2 synthesis and the increase of vascular permeability . Increased ZNF217 and decreased TSP-1 provided new targets for the prevention or treatment of OHSS | Zinc finger gene 217 (ZNF217) Promoted Ovarian Hyperstimulation Syndrome (OHSS) through Regulating E(2) Synthesis and Inhibiting Thrombospondin-1 (TSP-1).
Zhai J, Liu J, Cheng X, Li S, Hong Y, Sun K, Chen ZJ, Du Y, Li W., Free PMC Article | 06/8/2019 |
| this study underscored that elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin -conducted iron egress | Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress.
Jiang X, Zhang C, Qi S, Guo S, Chen Y, Du E, Zhang H, Wang X, Liu R, Qiao B, Yang K, Zhang Z, Xu Y., Free PMC Article | 02/24/2018 |
| this paper shows that hypoxia-inducible factors regulate pluripotency factor expression by ZNF217-mediated modulation of RNA methylation in breast cancer cells | Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Zhang C, Zhi WI, Lu H, Samanta D, Chen I, Gabrielson E, Semenza GL., Free PMC Article | 02/24/2018 |
| ZNF217 overexpression is associated with neoplasms. | Oncogenic protein SALL4 and ZNF217 as prognostic indicators in solid cancers: a meta‑analysis of individual studies.
Cheng J, Gao J, Shuai X, Tao K., Free PMC Article | 01/20/2018 |
| GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression. | GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression.
Jiang X, Chen Y, Du E, Yang K, Zhang Z, Qi S, Xu Y. | 12/2/2017 |
| ZNF217 regulates N6-methyladenosine mRNA deposition in embryonic stem cells thus contributing to tumorigenesis by dysregulating gene expression programs. | ZNF217/ZFP217 Meets Chromatin and RNA.
Lee DF, Walsh MJ, Aguiló F., Free PMC Article | 08/5/2017 |
| The report shows that the ZNF217 oncogene is a crucial mediator and indicator of bone metastasis from breast cancer. | The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone.
Bellanger A, Donini CF, Vendrell JA, Lavaud J, Machuca-Gayet I, Ruel M, Vollaire J, Grisard E, Győrffy B, Bièche I, Peyruchaud O, Coll JL, Treilleux I, Maguer-Satta V, Josserand V, Cohen PA. | 05/13/2017 |
| findings indicate that lncRNA-ATB governs the autocrine secretion of TGF-beta2 in KFs, at least in part, by downregulating the expression level of ZNF217 via miR-200c, suggesting a signaling axis consisting of lncRNA-ATB/miR-200c/ZNF217/TGF-beta2 | Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts.
Zhu HY, Bai WD, Li C, Zheng Z, Guan H, Liu JQ, Yang XK, Han SC, Gao JX, Wang HT, Hu DH., Free PMC Article | 05/7/2017 |
| Review: highlight the downstream molecular targets and signaling pathways of ZNF217 in tumor cells. | The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value.
Cohen PA, Donini CF, Nguyen NT, Lincet H, Vendrell JA., Free PMC Article | 10/1/2016 |
| High expression of ZNF217 is associated with enhanced cell migration and invasion in colorectal carcinoma. | ZNF217 is overexpressed and enhances cell migration and invasion in colorectal carcinoma.
Zhang ZC, Zheng LQ, Pan LJ, Guo JX, Yang GS. | 02/6/2016 |
| Two polymorphisms in ZNF217 in Mexican patients with colorectal cancer, were studied. | Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population.
Ramírez-Ramírez R, Gutiérrez-Angulo M, Magaña MT, Moreno-Ortiz JM, Partida-Pérez M, Muñiz-Mendoza R, Peregrina-Sandoval J, Suárez-Villanueva AS, Centeno-Flores M, Maciel-Gutiérrez VM, Cabrales-Vazquez E, Ayala-Madrigal ML. | 01/23/2016 |
| we conclude that ZNF217 may contribute to ovarian cancer invasion and metastasis, and associated with worse clinical outcomes. | ZNF217 is associated with poor prognosis and enhances proliferation and metastasis in ovarian cancer.
Li J, Song L, Qiu Y, Yin A, Zhong M., Free PMC Article | 05/30/2015 |
| Synergic effects of loss of ARID1A and PI3K-Akt pathway activation as well as ZNF217 amplification may be related to the development of ovarian clear cell carcinoma. | Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations and ZNF217 amplification in ovarian clear cell carcinoma.
Huang HN, Lin MC, Huang WC, Chiang YC, Kuo KT. | 02/28/2015 |
| ERalpha expression highly correlates with ZNF217 in lysates from breast tumors. | Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha.
Frietze S, O'Geen H, Littlepage LE, Simion C, Sweeney CA, Farnham PJ, Krig SR., Free PMC Article | 02/21/2015 |
| ZNF217 expression seems to be a novel prognostic biomarker in gastric cancer. | Prognostic significance of ZNF217 expression in gastric carcinoma.
Shida A, Fujioka S, Kurihara H, Ishibashi Y, Mitsumori N, Omura N, Yanaga K. | 11/22/2014 |