Associations of the obesity gene FTO variant with complications and comorbidities in patients with type 1 diabetes. | Associations of the obesity gene FTO variant with complications and comorbidities in patients with type 1 diabetes. Słomiński B, Skrzypkowska M, Myśliwiec M, Trzonkowski P. | 06/7/2024 |
Fat mass and obesity-associated protein (FTO) mediated m[6]A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay. | Fat mass and obesity-associated protein (FTO) mediated m(6)A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay. Wu X, Fang Y, Gu Y, Shen H, Xu Y, Xu T, Shi R, Xu D, Zhang J, Leng K, Shu Y, Ma P., Free PMC Article | 06/5/2024 |
FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner. | FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner. Yin Z, Guo X, Liang X, Wang Z. | 05/22/2024 |
FTO Positively Regulates Odontoblastic Differentiation via SMOC2 in Human Stem Cells from the Apical Papilla under Inflammatory Microenvironment. | FTO Positively Regulates Odontoblastic Differentiation via SMOC2 in Human Stem Cells from the Apical Papilla under Inflammatory Microenvironment. Huang Q, Sun Y, Huang W, Zhang F, He H, He Y, Huang F., Free PMC Article | 05/13/2024 |
FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3. | FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3. Xie W, Shao Y, Bo Q, Li Z, Yu Q, Wang L, Wu G. | 04/25/2024 |
FTO protein regulates the TGF-beta signalling pathway through RNA N6-methyladenosine modification to induce unexplained recurrent spontaneous abortion. | FTO protein regulates the TGF-β signalling pathway through RNA N6-methyladenosine modification to induce unexplained recurrent spontaneous abortion. Zhang J, Liu X, Gao Y. | 04/15/2024 |
circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis. | circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis. Liu Q, Xu P, Jin M, Wang L, Hu F, Yang Q, Bi R, Xiao H, Jiang L, Ding F., Free PMC Article | 04/4/2024 |
MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury. | MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury. Zhang C, Guan G, Wang J, Wei H, Cai J., Free PMC Article | 04/3/2024 |
Efficacy of a Comprehensive Weight Reduction Intervention in Male Adolescents With Different FTO Genotypes. | Efficacy of a Comprehensive Weight Reduction Intervention in Male Adolescents With Different FTO Genotypes. Roumi Z, Salimi Z, Mahmoudi Z, Mobarakeh KA, Ladaninezhad M, Zeinalabedini M, Keshavarz Mohammadian M, Shamsi-Goushki A, Saeedirad Z, Bahar B, Khoshdooz S, Kalantari N, Azizi Tabesh G, Doaei S, Gholamalizadeh M., Free PMC Article | 04/2/2024 |
The rs1477196 SNP of the FTO Gene is Associated with Primary Knee Osteoarthritis in a Female Population from Northern Mexico. | The rs1477196 SNP of the FTO Gene is Associated with Primary Knee Osteoarthritis in a Female Population from Northern Mexico. Arellano-Pérez-Vertti RD, González-Galarza FF, Prone-Olazábal D, Arellano-Ramírez DO, Arellano-Ramírez DF, Argüello-Beltrán CS, Tovar-Aguilar MA, Berúmen-Rodríguez M, Prieto-Hinojosa AI, Méndez-Hernández A, Argüello-Astorga R. | 03/14/2024 |
The m[6]A demethylase FTO targets POLQ to promote ccRCC cell proliferation and genome stability maintenance. | The m(6)A demethylase FTO targets POLQ to promote ccRCC cell proliferation and genome stability maintenance. He Y, Chen Y, Li Z, Wu C., Free PMC Article | 02/27/2024 |
Exosome-shuttled FTO from BM-MSCs contributes to cancer malignancy and chemoresistance in acute myeloid leukemia by inducing m6A-demethylation: A nano-based investigation. | Exosome-shuttled FTO from BM-MSCs contributes to cancer malignancy and chemoresistance in acute myeloid leukemia by inducing m6A-demethylation: A nano-based investigation. Kou R, Li T, Fu C, Jiang D, Wang Y, Meng J, Zhong R, Liang C, Dong M. | 02/22/2024 |
Evaluation of the role of FTO (rs9939609) and MC4R (rs17782313) gene polymorphisms in type 1 diabetes and their relation to obesity. | Evaluation of the role of FTO (rs9939609) and MC4R (rs17782313) gene polymorphisms in type 1 diabetes and their relation to obesity. Mosaad YM, Morzak M, Abd El Aziz El Chennawi F, Elsharkawy AA, Abdelsalam M. | 02/14/2024 |
Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and beta-cell function: In vitro studies using INS-1 cells and human pancreatic islets. | Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and β-cell function: In vitro studies using INS-1 cells and human pancreatic islets. Taneera J, Khalique A, Abdrabh S, Mohammed AK, Bouzid A, El-Huneidi W, Bustanji Y, Sulaiman N, Albasha S, Saber-Ayad M, Hamad M. | 02/12/2024 |
FTO is a major genetic link between breast cancer, obesity, and diabetes. | FTO is a major genetic link between breast cancer, obesity, and diabetes. Gholami M. | 01/29/2024 |
RNA N6-methyladenosine demethylase FTO targets MOXD1 promoting the malignant phenotype of gastric cancer. | RNA N6-methyladenosine demethylase FTO targets MOXD1 promoting the malignant phenotype of gastric cancer. Lai Y, Dong H, Xu P, Wang J, Feng W, Zhao Z, Sha L., Free PMC Article | 01/16/2024 |
Disruption of CerS6-mediated sphingolipid metabolism by FTO deficiency aggravates ulcerative colitis. | Disruption of CerS6-mediated sphingolipid metabolism by FTO deficiency aggravates ulcerative colitis. Ma Y, Zhang X, Xuan B, Li D, Yin N, Ning L, Zhou YL, Yan Y, Tong T, Zhu X, Huang X, Hu M, Wang Z, Cui Z, Li H, Wang J, Fang JY, Liu R, Chen H, Hong J. | 01/9/2024 |
FTO genotypes (rs9939609 T>A) are Associated with Increased Added Sugar Intake in Healthy Young Adults. | FTO genotypes (rs9939609 T>A) are Associated with Increased Added Sugar Intake in Healthy Young Adults. Madrigal-Juarez A, Martínez-López E, Sanchez-Murguia T, Magaña-de la Vega L, Rodriguez-Echevarria R, Sepulveda-Villegas M, Torres-Valadez R, Torres-Castillo N. | 01/6/2024 |
Characteristics of n6-methyladenosine (m6A) regulators and role of FTO/TNC in scleroderma. | Characteristics of n6-methyladenosine (m6A) regulators and role of FTO/TNC in scleroderma. Yu Y, Liang C, Tang Q, Shi Y, Shen L. | 01/5/2024 |
Minor alleles of FTO rs9939609 and rs17817449 polymorphisms confer a higher risk of type 2 diabetes mellitus and dyslipidemia, but not coronary artery disease in a Chinese Han population. | Minor alleles of FTO rs9939609 and rs17817449 polymorphisms confer a higher risk of type 2 diabetes mellitus and dyslipidemia, but not coronary artery disease in a Chinese Han population. Zhang Y, Chen L, Zhu J, Liu H, Xu L, Wu Y, He C, Song Y., Free PMC Article | 01/3/2024 |
FTO variation and early frontostriatal brain development in children. | FTO variation and early frontostriatal brain development in children. Thapaliya G, Kundu P, Jansen E, Naymik MA, Lee R, Bruchhage MMK, D'Sa V, Huentelman MJ, Lewis CR, Müller HG, Deoni SCL, RESONANCE consortium, Carnell S., | 01/3/2024 |
Increased m6A-RNA methylation and demethylase FTO suppression is associated with silica-induced pulmonary inflammation and fibrosis. | Increased m6A-RNA methylation and demethylase FTO suppression is associated with silica-induced pulmonary inflammation and fibrosis. Xu Y, Wang L, Qian R, Zhao M, Chen X, Sun D, Wang Y, Cheng W, Chen Y, He Q, Dai Y, Yao Y. | 12/21/2023 |
FTO up-regulation induced by MYC suppresses tumour progression in Epstein-Barr virus-associated gastric cancer. | FTO up-regulation induced by MYC suppresses tumour progression in Epstein-Barr virus-associated gastric cancer. Xu YY, Li T, Shen A, Bao XQ, Lin JF, Guo LZ, Meng Q, Ruan DY, Zhang QH, Zuo ZX, Zeng ZL., Free PMC Article | 12/20/2023 |
Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study. | Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study. Amin USM, Rahman TA, Hasan M, Tofail T, Hasanat MA, Seraj ZI, Salimullah M., Free PMC Article | 12/5/2023 |
N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway. | N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway. Jing YX, Li HX, Yue F, Li YM, Yu X, He JJ, Zhang XH. | 11/28/2023 |