| FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway. | FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway.
Sun X, Zhou L, Wang X, Li Y, Liu X, Chen Y, Zhong Z, Chen J. | 12/3/2022 |
| A Novel Mutation in the FYCO1 Gene Causing Congenital Cataract: Case Study of a Chinese Family. | A Novel Mutation in the FYCO1 Gene Causing Congenital Cataract: Case Study of a Chinese Family.
Mei S, Lin J, Liu Z, Li C., Free PMC Article | 09/10/2022 |
| Targeted gene sequencing of FYCO1 identified a novel mutation in a Pakistani family for autosomal recessive congenital cataract. | Targeted gene sequencing of FYCO1 identified a novel mutation in a Pakistani family for autosomal recessive congenital cataract.
Saleem RS, Siddiqui SN, Irshad S, Ashraf NM, Hamid A, Khan MAU, Khan MI, Micheal S., Free PMC Article | 08/13/2022 |
| Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1. | Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Xiao W, Yeerken D, Li J, Li Z, Jiang L, Li D, Fu M, Ma L, Song Y, Zhang W, Zhan Q., Free PMC Article | 03/12/2022 |
| Autosomal recessive cataract (CTRCT18) in the Yakut population isolate of Eastern Siberia: a novel founder variant in the FYCO1 gene. | Autosomal recessive cataract (CTRCT18) in the Yakut population isolate of Eastern Siberia: a novel founder variant in the FYCO1 gene.
Barashkov NA, Konovalov FA, Borisova TV, Teryutin FM, Solovyev AV, Pshennikova VG, Sapojnikova NV, Vychuzhina LS, Romanov GP, Gotovtsev NN, Morozov IV, Bondar AA, Platonov FA, Burtseva TE, Khusnutdinova EK, Posukh OL, Fedorova SA., Free PMC Article | 02/5/2022 |
| Identification of a novel nonsense variant in FYCO1 gene associated with infantile cataract and cortical atrophy. | Identification of a novel nonsense variant in FYCO1 gene associated with infantile cataract and cortical atrophy.
Aprahamian R, Yammine T, Salem N, Souaid M, Mansour H, Farra C. | 02/5/2022 |
| Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants. | Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants.
Cotroneo CE, Mangano N, Dragani TA, Colombo F., Free PMC Article | 06/26/2021 |
| Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases. | Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases.
Sakurai S, Shimizu T, Ohto U., Free PMC Article | 06/12/2021 |
| FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation | FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation.
Dionne LK, Peterman E, Schiel J, Gibieža P, Skeberdis VA, Jimeno A, Wang XJ, Prekeris R., Free PMC Article | 08/4/2018 |
| FYCO1 and MAP1LC3A interact through a novel binding mode that involves Atg8-family proteins | Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins.
Cheng X, Wang Y, Gong Y, Li F, Guo Y, Hu S, Liu J, Pan L., Free PMC Article | 01/6/2018 |
| Rare missense variants in FYCO1 are overrepresented in sporadic inclusion body myositis patients. | Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis.
Güttsches AK, Brady S, Krause K, Maerkens A, Uszkoreit J, Eisenacher M, Schreiner A, Galozzi S, Mertens-Rill J, Tegenthoff M, Holton JL, Harms MB, Lloyd TE, Vorgerd M, Weihl CC, Marcus K, Kley RA., Free PMC Article | 07/1/2017 |
| FYCO1 requires a functional LC3A/B-preferring LC3-interacting Region (LIR) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected | FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy.
Olsvik HL, Lamark T, Takagi K, Larsen KB, Evjen G, Øvervatn A, Mizushima T, Johansen T., Free PMC Article | 04/23/2016 |
| FYCO1 is involved in lens development and transparency in humans, and mutations in this gene are one of the most common causes of autosomal-recessive congenital cataracts in the Pakistani population. | Mutations in FYCO1 cause autosomal-recessive congenital cataracts.
Chen J, Ma Z, Jiao X, Fariss R, Kantorow WL, Kantorow M, Pras E, Frydman M, Pras E, Riazuddin S, Riazuddin SA, Hejtmancik JF., Free PMC Article | 08/20/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. | 04/7/2010 |
| We have characterized the LC3-, Rab7-, and phosphatidylinositol-3-phosphate-binding domains in FYCO1 and mapped part of the CC region essential for MT plus end-directed transport. | FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport.
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T., Free PMC Article | 03/1/2010 |
| Maps to a region of chromosome 3p21.3 which is frequently deleted in tumors. | The transcriptional map of the common eliminated region 1 (C3CER1) in 3p21.3.
Kiss H, Yang Y, Kiss C, Andersson K, Klein G, Imreh S, Dumanski JP. | 01/21/2010 |