| The deubiquitinase OTUD1 deubiquitinates TIPE2 and plays a protective role in sepsis-induced lung injury by targeting TAK1-mediated MAPK and NF-kappaB signaling. | The deubiquitinase OTUD1 deubiquitinates TIPE2 and plays a protective role in sepsis-induced lung injury by targeting TAK1-mediated MAPK and NF-κB signaling.
Ming T, Liu H, Yuan M, Tian J, Fang Q, Liu Y, Kong Q, Wang Q, Song X, Xia Z, Wu X. | 09/24/2024 |
| TIPE2 inhibits the migration and invasion of epithelial ovarian cancer cells by targeting Smad2 to reverse TGF-beta1-induced EMT. | TIPE2 inhibits the migration and invasion of epithelial ovarian cancer cells by targeting Smad2 to reverse TGF-β1-induced EMT.
Tang Z, Zhang D, Yao C, Jiang M, Wang C, Chen Z, Yu H, Xue C, Liu Y, Shi Y, Zhang L, Wang X, Wei Z. | 09/17/2024 |
| Tumor Necrosis Factor-alpha-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells. | Tumor Necrosis Factor-α-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells.
Li J, He X, Liu F, Zheng X, Jiang J. | 01/9/2024 |
| TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2-NF-kappaB signaling pathway. | TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2-NF-κB signaling pathway.
Yuan M, Jing G, Kong Q, Ming T, Zuo J, Wang Q, Feng Y, Liu W, Wu X, Xia Z. | 11/8/2023 |
| Implication of TIPE2 Expression on the Malignant Transformation of Oral Leukoplakia. | Implication of TIPE2 Expression on the Malignant Transformation of Oral Leukoplakia.
Chen H, Pei M, Shin SW, Moon S, Nam W, Zheng Z. | 11/3/2023 |
| Research progress of TIPE2 in immune-related diseases. | Research progress of TIPE2 in immune-related diseases.
Gao J, Zhang H, Zhang F. | 10/24/2023 |
| TIPE2 regulates the response of BV2 cells to lipopolysaccharide by the crosstalk between PI3K/AKT signaling and microglia M1/M2 polarization. | TIPE2 regulates the response of BV2 cells to lipopolysaccharide by the crosstalk between PI3K/AKT signaling and microglia M1/M2 polarization.
Gao J, Wang N, Zong F, Dong J, Lin Y, Zhang H, Zhang F. | 06/24/2023 |
| TIPE2 sensitizes breast cancer cells to paclitaxel by suppressing drug-induced autophagy and cancer stem cell properties. | TIPE2 sensitizes breast cancer cells to paclitaxel by suppressing drug-induced autophagy and cancer stem cell properties.
Hu W, Zheng W, Du J, Tian Z, Zhao Y, Zhao P, Li J. | 06/23/2023 |
| TIPE2 acts as a tumor suppressor and correlates with tumor microenvironment immunity in epithelial ovarian cancer. | TIPE2 acts as a tumor suppressor and correlates with tumor microenvironment immunity in epithelial ovarian cancer.
Xu S, Gao X, Qiu J, Hong F, Gao F, Wang X, Zhang S., Free PMC Article | 03/14/2023 |
| TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma. | TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Shi B, Hao Y, Li W, Dong H, Xu M, Gao P., Free PMC Article | 05/21/2022 |
| Tumor Necrosis Factor-alpha-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer. | Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
Lou Y, Song M, Han M, Zhong J, Tian X, Ren Y, Song Y, Duan L, Zhao P, Song X, Zhang W, Chen YH, Wang H. | 05/7/2022 |
| TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity. | TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Bi J, Cheng C, Zheng C, Huang C, Zheng X, Wan X, Chen YH, Tian Z, Sun H., Free PMC Article | 04/16/2022 |
| TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis. | TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis.
Li W, Li Y, Guan Y, Du Y, Zhao M, Chen X, Zhu F, Guo C, Jia Y, Li Y, Wang X, Wang X, Shi Y, Wang Q, Li Y, Zhang L., Free PMC Article | 01/1/2022 |
| A novel prognostic factor TIPE2 inhibits cell proliferation and promotes apoptosis in pancreatic ductal adenocarcinoma (PDAC). | A novel prognostic factor TIPE2 inhibits cell proliferation and promotes apoptosis in pancreatic ductal adenocarcinoma (PDAC).
Sun Y, Cao S, Li Z, Liu X, Xu J, Tian Y, Shen S, Zhou Y., Free PMC Article | 11/6/2021 |
| TIPE2 and PCNP expression abnormalities in peripheral blood mononuclear cells associated with disease activity in rheumatoid arthritis: a meta-analysis. | TIPE2 and PCNP expression abnormalities in peripheral blood mononuclear cells associated with disease activity in rheumatoid arthritis: a meta-analysis.
Han ZP, Yang Y, Chen HY, Zhong MY, Zhuang GH. | 09/18/2021 |
| Down-regulation of anti-inflammatory TIPE2 may aggravate adenoidal hypertrophy in children. | Down-regulation of anti-inflammatory TIPE2 may aggravate adenoidal hypertrophy in children.
Gao K, Li Y, Yue Z, Han J, Zhou X, Wang X., Free PMC Article | 07/10/2021 |
| TIPE2 suppresses progression and tumorigenesis of the oral tongue squamous cell carcinoma by regulating FoxP3(+) regulatory T cells. | TIPE2 suppresses progression and tumorigenesis of the oral tongue squamous cell carcinoma by regulating FoxP3(+) regulatory T cells.
Zhao LL. | 06/26/2021 |
| Decreased expression of TIPE2 in the eye under high-glucose conditions tested in vivo and in vitro. | Decreased expression of TIPE2 in the eye under high-glucose conditions tested in vivo and in vitro.
Suo LG, Qin RX, Cui YY, Qin XJ. | 06/19/2021 |
| TIPE2 inhibits the migration and invasion of endometrial cells by targeting beta-catenin to reverse epithelial-mesenchymal transition. | TIPE2 inhibits the migration and invasion of endometrial cells by targeting β-catenin to reverse epithelial-mesenchymal transition.
Liu Y, Wang X, Wan L, Liu X, Yu H, Zhang D, Sun Y, Shi Y, Zhang L, Zhou H, Wang J, Wei Z. | 05/8/2021 |
| Microarray gene expression profiling provides insights into functions of TIPE2 in HBV-related apoptosis. | Microarray gene expression profiling provides insights into functions of TIPE2 in HBV-related apoptosis.
Cui J, Zhang N, Liu Y, Zhang L, Gao C, Liu S. | 04/3/2021 |
| The SCF(beta-TrCP) E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2. | The SCF(β-TrCP) E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Lou Y, Han M, Song Y, Zhong J, Zhang W, Chen YH, Wang H. | 01/2/2021 |
| TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. | TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis.
Yan D, Wang J, Sun H, Zamani A, Zhang H, Chen W, Tang A, Ruan Q, Yang X, Chen YH, Wan X., Free PMC Article | 09/12/2020 |
| TIPE2 Induced the Proliferation, Survival, and Migration of Lung Cancer Cells Through Modulation of Akt/mTOR/NF-kappaB Signaling Cascade. | TIPE2 Induced the Proliferation, Survival, and Migration of Lung Cancer Cells Through Modulation of Akt/mTOR/NF-κB Signaling Cascade.
Bordoloi D, Banik K, Padmavathi G, Vikkurthi R, Harsha C, Roy NK, Singh AK, Monisha J, Wang H, Kumar AP, Kunnumakkara AB., Free PMC Article | 09/5/2020 |
| High TIPE2 expression is associated with proliferation, migration, and invasion in rectal adenocarcinoma. | Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
Wu DD, Liu SY, Gao YR, Lu D, Hong Y, Chen YG, Dong PZ, Wang DY, Li T, Li HM, Ren ZG, Guo JC, He F, Ren XQ, Sun SY, Duan SF, Ji XY., Free PMC Article | 07/25/2020 |
| aberrant TIPE2 expression may contribute to the occurrence of chemoresistance by interfering with autophagy in non-small-cell lung cancer in an mTOR-dependent manner. | TIPE2 suppressed cisplatin resistance by inducing autophagy via mTOR signalling pathway.
Guo H, Ren H, Li J, Hao M, Hao J, Ren H, Guo L, Liu R. | 07/25/2020 |