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    AGMAT agmatinase (putative) [ Homo sapiens (human) ]

    Gene ID: 79814, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR151a5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.

    miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
    Xie Y, Zhang Y, Liu X, Cao L, Han M, Wang C, Chen J, Zhang X., Free PMC Article

    02/4/2023
    Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.

    Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway.
    Zhu HE, Yin JY, Chen DX, He S, Chen H., Free PMC Article

    09/5/2020
    Enzymes that are directly involved in the formation of urea are expressed in ocular tissues.

    Enzymes of urea synthesis are expressed at the ocular surface, and decreased urea in the tear fluid is associated with dry-eye syndrome.
    Jäger K, Kielstein H, Dunse M, Nass N, Paulsen F, Sel S.

    12/28/2013
    This study demonistrated that increased expression of agmatinase in hippocampal interneurons of subjects with mood disorders.

    Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders.
    Bernstein HG, Stich C, Jäger K, Dobrowolny H, Wick M, Steiner J, Veh R, Bogerts B, Laube G.

    08/18/2012
    Agmatinase activity was predominantly detected in neurons of rat and human brain.

    The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?
    Bernstein HG, Derst C, Stich C, Prüss H, Peters D, Krauss M, Bogerts B, Veh RW, Laube G.

    05/28/2011
    Observational study of gene-disease association. (HuGE Navigator)

    Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article

    12/5/2010
    Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

    Novel association strategy with copy number variation for identifying new risk Loci of human diseases.
    Chen X, Li X, Wang P, Liu Y, Zhang Z, Zhao G, Xu H, Zhu J, Qin X, Chen S, Hu L, Kong X., Free PMC Article

    12/5/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    X-ray crystallographic analysis of human agmatinase

    Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase.
    Kim KH, Ahn HJ, Kim DJ, Lee HH, Ha JY, Kim HK, Yoon HJ, Suh SW., Free PMC Article

    01/21/2010
    an alternative to ornithine decarboxylase for polyamine biosynthesis

    Cloning of human agmatinase. An alternate path for polyamine synthesis induced in liver by hepatitis B virus.
    Mistry SK, Burwell TJ, Chambers RM, Rudolph-Owen L, Spaltmann F, Cook WJ, Morris SM Jr.

    01/21/2010
    Agmatinase is down-regulated in the clear cell type of renal cell carcinoma

    Human agmatinase is diminished in the clear cell type of renal cell carcinoma.
    Dallmann K, Junker H, Balabanov S, Zimmermann U, Giebel J, Walther R.

    01/21/2010
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