Calcitonin/PAC1 receptor splice variants: a blind spot in migraine research. | Calcitonin/PAC(1) receptor splice variants: a blind spot in migraine research. Rees TA, Labastida-Ramírez A, Rubio-Beltrán E., | 10/26/2023 |
Polymorphisms in Genes Encoding VDR, CALCR and Antioxidant Enzymes as Predictors of Bone Tissue Condition in Young, Healthy Men. | Polymorphisms in Genes Encoding VDR, CALCR and Antioxidant Enzymes as Predictors of Bone Tissue Condition in Young, Healthy Men. Jówko E, Długołęcka B, Cieśliński I, Kotowska J., Free PMC Article | 03/1/2023 |
Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions. | Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions. Ali FT, El-Azeem EMA, Hekal HFA, El-Gizawy MM, Sayed MS, Mandoh AY, Soliman AF., Free PMC Article | 10/29/2022 |
Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1. | Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1. Kar S, Sen S, Maji S, Saraf D, Ruturaj, Paul R, Dutt S, Mondal B, Rodriguez-Boulan E, Schreiner R, Sengupta D, Gupta A., Free PMC Article | 04/30/2022 |
Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion. | Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion. Walke G, Aupič J, Kashoua H, Janoš P, Meron S, Shenberger Y, Qasem Z, Gevorkyan-Airapetov L, Magistrato A, Ruthstein S., Free PMC Article | 04/16/2022 |
Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults. | Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults. Song E, Jeon MJ, Yoo HJ, Bae SJ, Kim TY, Kim WB, Shong YK, Kim HK, Kim WG., Free PMC Article | 03/19/2022 |
Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer's Disease Mouse Models. | Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer's Disease Mouse Models. Patel A, Kimura R, Fu W, Soudy R, MacTavish D, Westaway D, Yang J, Davey RA, Zajac JD, Jhamandas JH., Free PMC Article | 02/5/2022 |
CALCR knockdown inhibits the development and progression of non-small-cell lung cancer. | CALCR knockdown inhibits the development and progression of non-small-cell lung cancer. He T, Ling F. | 01/1/2022 |
CALCR rs1801197 might be associated with increased risk of calcium stone urolithiasis. There is insufficient data to fully confirm the association between CALCR rs1042138 and calcium stone urolithiasis susceptibility (Meta-Analysis) | Association between calcitonin receptor gene polymorphisms and calcium stone urolithiasis: A meta-analysis. Qin J, Cai Z, Xing J, Duan B, Bai P., Free PMC Article | 01/18/2020 |
CTR activates AKAP2-anchored cAMP-dependent protein kinase A, which then phosphorylates tight junction proteins ZO-1 and claudin 3. | Calcitonin receptor increases invasion of prostate cancer cells by recruiting zonula occludens-1 and promoting PKA-mediated TJ disassembly. Aljameeli A, Thakkar A, Shah G. | 03/10/2018 |
structure of a full-length class B receptor, the calcitonin receptor, in complex with peptide ligand and heterotrimeric Galphasbetagamma protein determined by Volta phase-plate single-particle cryo-electron microscopy | Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM., Free PMC Article | 10/14/2017 |
Data suggest that a single GlcNAc residue at CTR N130 (asparagine 130) is responsible for enhanced affinity of calcitonin for CTR ECD; the same appears to apply for enhanced affinity of amylin for RAMP2-CTR ECD. [GlcNAc = N-acetylglucosamine; CTR = calcitonin receptor; ECD = extracellular domain; RAMP2 = receptor (calcitonin) activity modifying protein 2]. | N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity. Lee SM, Booe JM, Gingell JJ, Sjoelund V, Hay DL, Pioszak AA., Free PMC Article | 07/29/2017 |
Males with CALCR TT genotype (rs1801197) have 13 fold increased risk for kidney stone disease. No significant association of rs1042138 with kidney stone in West Bengal, India. | Association of calcitonin receptor gene (CALCR) polymorphism with kidney stone disease in the population of West Bengal, India. Mitra P, Guha M, Ghosh S, Mukherjee S, Bankura B, Pal DK, Maity B, Das M. | 06/24/2017 |
Calcitonin and Amylin Receptor Peptide Interaction Mechanisms: INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYING PROTEINS. | Calcitonin and Amylin Receptor Peptide Interaction Mechanisms: INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYING PROTEINS. Lee SM, Hay DL, Pioszak AA., Free PMC Article | 10/8/2016 |
An association between fluorosis and the Alu I polymorphism in the CTR gene was observed in fluoride-exposed populations. | The relationship between Alu I polymorphisms in the calcitonin receptor gene and fluorosis endemic to Chongqing, China. Jiang M, Mu L, Wang Y, Yan W, Jiao Y., Free PMC Article | 10/17/2015 |
The C1377T polymorphism in the CTR gene is associated with bone mineral density at the lumbar spine in a postmenopausal Han Chinese population | Association of calcitonin receptor gene polymorphism with bone mineral density in postmenopausal Chinese women: a meta-analysis. Zhang H, Tao X, Wu J. | 06/6/2015 |
There was no statistically significant difference in CTR gene nucleotide sequence polymorphisms at 1377-bp between Chinese Xinjiang Han and Uygur patients with primary osteoporosis. | Calcitonin receptor gene polymorphism in cCinese Xinjiang Han and Uygur women with primary osteoporosis. Xu J, Gao Y, Yin J, Zhao X, Wang H, Yuan H, Wang F. | 05/30/2015 |
Data indicate a potential association between 3'UTR+18C>T and intron 1 polymorphisms in the CALCR and the risk of kidney stone disease. | Genetic polymorphisms in calcitonin receptor gene and risk for recurrent kidney calcium stone disease. Shakhssalim N, Basiri A, Houshmand M, Pakmanesh H, Golestan B, Azadvari M, Aryan H, Kashi AH. | 02/28/2015 |
Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias. | Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias. Andreassen KV, Hjuler ST, Furness SG, Sexton PM, Christopoulos A, Nosjean O, Karsdal MA, Henriksen K., Free PMC Article | 12/20/2014 |
High calcitonin receptor is associated with prostate cancer. | Profiling of the calcitonin-calcitonin receptor axis in primary prostate cancer: clinical implications and molecular correlates. Thakkar A, Bijnsdorp IV, Geldof AA, Shah GV., Free PMC Article | 06/14/2014 |
the polymorphic genotypes of BGLAP, ER1, Col1A1 and CALCR are not found to be associated with osteoporosis in a single form but found to be associated in combined forms. | Association between osteoporosis and polymorphisms of the bone Gla protein, estrogen receptor 1, collagen 1-A1 and calcitonin receptor genes in Turkish postmenopausal women. Tural S, Kara N, Alayli G, Tomak L. | 03/23/2013 |
CTR was expressed by glioma cells in a majority of GBM tumours tested. | The expression of calcitonin receptor detected in malignant cells of the brain tumour glioblastoma multiforme and functional properties in the cell line A172. Wookey PJ, McLean CA, Hwang P, Furness SG, Nguyen S, Kourakis A, Hare DL, Rosenfeld JV. | 08/18/2012 |
Allele C in CALCR gene was associated with reduced bone mass in cystic fibrosis children. | [Genetic risk markers of low bone mineral density in cystic fibrosis children]. Norek A, Sands D, Sobczyńska-Tomaszewska A, Chmielewski D, Szamotulska K, Czerska K, Bal J. | 04/23/2011 |
highly expressed on normal T- and B-lymphocytes | Functional expression of the calcitonin receptor by human T and B cells. Cafforio P, De Matteo M, Brunetti AE, Dammacco F, Silvestris F. | 02/8/2010 |
Activation of calcitonin receptor and calcitonin receptor-like receptor by membrane-anchored ligands. | Activation of calcitonin receptor and calcitonin receptor-like receptor by membrane-anchored ligands. Chang CL, Park JI, Hsu SY., Free PMC Article | 02/1/2010 |