| Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy. | Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy.
Liu TT, Yang H, Zhuo FF, Yang Z, Zhao MM, Guo Q, Liu Y, Liu D, Zeng KW, Tu PF., Free PMC Article | 01/14/2023 |
| Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. | Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Zhong Y, Zhang ZH, Wang JY, Xing Y, Ri MH, Jin HL, Zuo HX, Li MY, Ma J, Jin X. | 09/10/2022 |
| Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1. | Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1.
Wu W, Nelson GM, Koch R, Donovan KA, Nowak RP, Heavican-Foral TB, Nirmal AJ, Liu H, Yang L, Duffy J, Powers F, Stevenson KE, Jones MK, Ng SY, Wu G, Jain S, Xu R, Amaka S, Trevisani C, Donaldson NL, Hagner PR, de Leval L, Gaulard P, Iqbal J, Thakurta A, Fischer ES, Adelman K, Weinstock DM., Free PMC Article | 04/9/2022 |
| ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. | ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells.
Wang F, Zhang Y, Yu X, Teng XL, Ding R, Hu Z, Wang A, Wang Z, Ye Y, Zou Q., Free PMC Article | 12/4/2021 |
| MicroRNA1885p inhibits the progression of breast cancer by targeting zinc finger protein 91. | MicroRNA‑188‑5p inhibits the progression of breast cancer by targeting zinc finger protein 91.
Yang Z, Liu Z, Chang Z, Yan G., Free PMC Article | 07/10/2021 |
| E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing. | E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing.
Chen D, Wang Y, Lu R, Jiang X, Chen X, Meng N, Chen M, Xie S, Yan GR., Free PMC Article | 05/22/2021 |
| Zinc finger protein 91 accelerates tumour progression by activating beta-catenin signalling in pancreatic cancer. | Zinc finger protein 91 accelerates tumour progression by activating β-catenin signalling in pancreatic cancer.
Tang N, Xu S, Song T, Qiu Y, He J, Fu X., Free PMC Article | 05/15/2021 |
| Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis. | Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis.
Harel S, Sanchez-Gonzalez V, Echavarria R, Mayaki D, Hussain SN., Free PMC Article | 03/13/2021 |
| The ubiquitinase ZFP91 promotes tumor cell survival and confers chemoresistance through FOXA1 destabilization. | The ubiquitinase ZFP91 promotes tumor cell survival and confers chemoresistance through FOXA1 destabilization.
Tang DE, Dai Y, Xu Y, Lin LW, Liu DZ, Hong XP, Ou ML, Jiang HW, Xu SH. | 08/22/2020 |
| research describes a mechanism by which ZFP91 promotes production of IL-1beta under physiological conditions and suggests that ZFP91 may be a promising therapeutic target for intervention in inflammatory, infectious and autoimmune-related diseases | Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome.
Mi C, Wang Z, Li MY, Zhang ZH, Ma J, Jin X., Free PMC Article | 09/28/2019 |
| our findings indicated that miR-188-5p serves as a tumor suppressor in human gastric cancer (GC)by targeting ZFP91, suggesting that miR-188-5p might be a promising therapeutic target for GC treatment | miR-188-5p Suppresses Gastric Cancer Cell Proliferation and Invasion via Targeting ZFP91.
Peng Y, Shen X, Jiang H, Chen Z, Wu J, Zhu Y, Zhou Y, Li J., Free PMC Article | 02/2/2019 |
| lenalidomide induces the ubiquitination and degradation of ZFP91 | pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4(CRBN) ubiquitin ligase.
An J, Ponthier CM, Sack R, Seebacher J, Stadler MB, Donovan KA, Fischer ES., Free PMC Article | 12/22/2018 |
| Data show that NF-kappaB/p65 is required for the binding of zinc finger protein 91 (ZFP91) to the HIF-1alpha promoter and for the transcriptional activation of HIF-1alpha gene mediated by ZFP91. | Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer.
Ma J, Mi C, Wang KS, Lee JJ, Jin X., Free PMC Article | 12/30/2017 |
| ZFP91 is overexpressed in prostate cancer. | ZFP91: A Noncanonical NF-κB Signaling Pathway Regulator with Oncogenic Properties Is Overexpressed in Prostate Cancer.
Paschke L, Jopek K, Szyszka M, Tyczewska M, Ziolkowska A, Rucinski M, Malendowicz LK., Free PMC Article | 02/18/2017 |
| hHgher protein levels of ZFP91 in all cancer cell lines. | ZFP91-a newly described gene potentially involved in prostate pathology.
Paschke L, Rucinski M, Ziolkowska A, Zemleduch T, Malendowicz W, Kwias Z, Malendowicz LK., Free PMC Article | 10/10/2015 |
| These data clearly indicate that ZFP91 is a key regulator in LIGHT-induced activation of non-canonical NF-kappaB pathway in LTbetaR signaling. | Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-κB pathway.
Jin HR, Jin X, Lee JJ. | 11/27/2010 |
| An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination. | An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination.
Jin X, Jin HR, Jung HS, Lee SJ, Lee JH, Lee JJ., Free PMC Article | 10/30/2010 |
| likely to play an important role in cell proliferation and/or anti-apoptosis, and may serve as a molecular marker for AML | Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Unoki M, Okutsu J, Nakamura Y. | 01/21/2010 |