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    HMGA2 high mobility group AT-hook 2 [ Homo sapiens (human) ]

    Gene ID: 8091, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Beneath HMGA2 alterations in pleomorphic adenomas: Pathological, immunohistochemical, and molecular insights.

    Beneath HMGA2 alterations in pleomorphic adenomas: Pathological, immunohistochemical, and molecular insights.
    Alsugair Z, Lépine C, Descotes F, Lanic MD, Pissaloux D, Tirode F, Lopez J, Céruse P, Philouze P, Fieux M, Wassef M, Baglin AC, Mihaela O, Castain C, Sudaka A, Uro-Coste E, Champagnac A, Costes-Martineau V, Laé M, Benzerdjeb N, REFCOR network*.

    09/24/2024
    HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration.

    HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration.
    Yang Y, Gao C, Li Q, Liu Y, Cao J.

    08/19/2024
    Peculiar nuclear atypia associated with MDM2 gene amplification in carcinoma ex-pleomorphic adenoma harbouring an alteration of HMGA2.

    Peculiar nuclear atypia associated with MDM2 gene amplification in carcinoma ex-pleomorphic adenoma harbouring an alteration of HMGA2.
    Alsugair Z, Fieux M, Descotes F, Lopez J, Cordonnier C, Russel J, Champagnac A, Pissaloux D, Céruse P, Philouze P, Benzerdjeb N.

    08/12/2024
    Chromatin modifier Hmga2 promotes adult hematopoietic stem cell function and blood regeneration in stress conditions.

    Chromatin modifier Hmga2 promotes adult hematopoietic stem cell function and blood regeneration in stress conditions.
    Kubota S, Sun Y, Morii M, Bai J, Ideue T, Hirayama M, Sorin S, Eerdunduleng, Yokomizo-Nakano T, Osato M, Hamashima A, Iimori M, Araki K, Umemoto T, Sashida G., Free PMC Article

    07/23/2024
    Effects of HMGA2 on the biological characteristics and stemness acquisition of gastric cancer cells.

    Effects of HMGA2 on the biological characteristics and stemness acquisition of gastric cancer cells.
    Kong D, Zha L, Yao Y, Zhang Z, Gao J, Zhang R, Chen L, Wang Z.

    06/10/2024
    Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.

    Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.
    Najibi K, Moghanibashi M, Naeimi S., Free PMC Article

    06/5/2024
    Exosomal circFAM63Bsuppresses bone regeneration of postmenopausal osteoporosis via regulating miR-578/HMGA2 axis.

    Exosomal circFAM63Bsuppresses bone regeneration of postmenopausal osteoporosis via regulating miR-578/HMGA2 axis.
    Li F, Zhao X, Zhang Y, Zhuang Q, Wang S, Fang X, Xu T, Li X, Chen G.

    05/13/2024
    Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring an HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With Metastatic Disease, and Review of the Literature.

    Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring an HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With Metastatic Disease, and Review of the Literature.
    Patton A, Ilaslan H, Armstrong SM, Bakhshwin A, Cheng YW, Minhas F, Fritchie KJ.

    04/23/2024
    Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome.

    Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome.
    Maharaj AV, Cottrell E, Thanasupawat T, Joustra SD, Triggs-Raine B, Fujimoto M, Kant SG, van der Kaay D, Clement-de Boers A, Brooks AS, Aguirre GA, Martín Del Estal I, Castilla de Cortázar Larrea MI, Massoud A, van Duyvenvoorde HA, De Bruin C, Hwa V, Klonisch T, Hombach-Klonisch S, Storr HL., Free PMC Article

    04/4/2024
    SOX10-Internal Tandem Duplications and PLAG1 or HMGA2 Fusions Segregate Eccrine-Type and Apocrine-Type Cutaneous Mixed Tumors.

    SOX10-Internal Tandem Duplications and PLAG1 or HMGA2 Fusions Segregate Eccrine-Type and Apocrine-Type Cutaneous Mixed Tumors.
    Macagno N, Kervarrec T, Thanguturi S, Sohier P, Pissaloux D, Mescam L, Jullie ML, Frouin E, Osio A, Faisant M, Le Loarer F, Cribier B, Calonje E, Luna EVE, Massi D, Goto K, Nishida H, Paindavoine S, Houlier A, Tantot J, Benzerdjeb N, Tirode F, De la Fouchardière A, Battistella M.

    03/26/2024
    The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway.

    The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway.
    Qian S, Wang F, Liao W, Liu J.

    03/22/2024
    CircDLGAP4 overexpression ameliorates neuronal injury in Parkinson's disease by binding to EIF4A3 and increasing HMGA2 expression.

    CircDLGAP4 overexpression ameliorates neuronal injury in Parkinson's disease by binding to EIF4A3 and increasing HMGA2 expression.
    Bao H, Zhang Q, Li Y, Nie C.

    01/26/2024
    LncRNA HAGLROS contribute to papillary thyroid cancer progression by modulating miR-206/HMGA2 expression.

    LncRNA HAGLROS contribute to papillary thyroid cancer progression by modulating miR-206/HMGA2 expression.
    Zeng Z, Tang S, Chen L, Hou H, Liu Y, Li J., Free PMC Article

    01/26/2024
    Expanding the histological spectrum of salivary gland neoplasms with HMGA2::WIF1 fusion emphasising their malignant potential: a report of eight cases.

    Expanding the histological spectrum of salivary gland neoplasms with HMGA2::WIF1 fusion emphasising their malignant potential: a report of eight cases.
    Katabi N, Sukhadia P, DiNapoli SE, Weinreb I, Hahn E, Ghossein R, Xu B.,

    12/28/2023
    LINC02454 promotes thyroid carcinoma progression via upregulating HMGA2 through CREB1.

    LINC02454 promotes thyroid carcinoma progression via upregulating HMGA2 through CREB1.
    Cao Y, Li J, Du Y, Sun Y, Liu L, Fang H, Liang Y, Mao S.

    11/28/2023
    C2orf48 promotes the progression of nasopharyngeal carcinoma by regulating high mobility group AT-hook 2.

    C2orf48 promotes the progression of nasopharyngeal carcinoma by regulating high mobility group AT-hook 2.
    Jiang Y, Liang F, Chen R, Huang Y, Xiao Z, Zeng H, Han P, Huang X.

    10/24/2023
    MicroRNA-143-5p Suppresses ER-Positive Breast Cancer Development by Targeting Oncogenic HMGA2.

    MicroRNA-143-5p Suppresses ER-Positive Breast Cancer Development by Targeting Oncogenic HMGA2.
    Mansoori B, Kiani S, Mezajin AA, Zandi P, Banaie H, Rostamzadeh D, Cho WC, Duijf PHG, Mansoori B, Baradaran B.

    10/11/2023
    Unraveling the Roles of miR-204-5p and HMGA2 in Papillary Thyroid Cancer Tumorigenesis.

    Unraveling the Roles of miR-204-5p and HMGA2 in Papillary Thyroid Cancer Tumorigenesis.
    Van Branteghem C, Augenlicht A, Demetter P, Craciun L, Maenhaut C., Free PMC Article

    09/11/2023
    Circular RNA circ_KIAA1429 accelerates hepatocellular carcinoma progression via the miR-133a-3p/high mobility group AT-hook 2 (HMGA2) axis in an m6A-dependent manner.

    Circular RNA circ_KIAA1429 accelerates hepatocellular carcinoma progression via the miR-133a-3p/high mobility group AT-hook 2 (HMGA2) axis in an m6A-dependent manner.
    Zhang CP, Huang XY.

    08/25/2023
    Mammary stromal-epithelial lesions with myofibroblastic stroma and HMGA2 overexpression linked smooth muscle differentiation, a case series from single institution.

    Mammary stromal-epithelial lesions with myofibroblastic stroma and HMGA2 overexpression linked smooth muscle differentiation, a case series from single institution.
    Abada E, Tseng Y, Sung CJ, Singh K.

    08/19/2023
    Proteomic analysis identifies HMGA2 as a novel biomarker of overall survival in papillary renal cell carcinoma.

    Proteomic analysis identifies HMGA2 as a novel biomarker of overall survival in papillary renal cell carcinoma.
    Wei T, Xu H, Liang H, Lian Y, Chen H, Zheng Z, Zhong M, Liu J, Wang R, Wang F., Free PMC Article

    07/23/2023
    MicroRNA-23a-3p overexpression represses proliferation and accelerates apoptosis of granular cells in polycystic ovarian syndrome by targeting HMGA2.

    MicroRNA-23a-3p overexpression represses proliferation and accelerates apoptosis of granular cells in polycystic ovarian syndrome by targeting HMGA2.
    Wei J, Cheng P, Kong M, Zhang L, Liu S, Ning B, Huang X.

    03/30/2023
    Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation.

    Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation.
    Panagopoulos I, Andersen K, Brunetti M, Gorunova L, Lund-Iversen M, Micci F, Heim S., Free PMC Article

    03/14/2023
    HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA-less cancer cells.

    HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA-less cancer cells.
    Maruyama T, Saito K, Higurashi M, Ishikawa F, Kohno Y, Mori K, Shibanuma M., Free PMC Article

    01/11/2023
    HMGA2 Synergizes with EZH2 to Mediate Epithelial Cell Inflammation and Apoptosis in Septic Lung Dysfunction.

    HMGA2 Synergizes with EZH2 to Mediate Epithelial Cell Inflammation and Apoptosis in Septic Lung Dysfunction.
    Shi L, Shi CW, Cheng KW.

    01/11/2023
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