| Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A). | Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A).
Schmelter C, Fomo KN, Brueck A, Perumal N, Markowitsch SD, Govind G, Speck T, Pfeiffer N, Grus FH., Free PMC Article | 08/9/2023 |
| Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage. | Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage.
Quintiens J, De Roover A, Cornelis FMF, Escribano-Núñez A, Sermon A, Pazmino S, Monteagudo S, Lories RJ. | 03/24/2023 |
| Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis. | Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis.
Swann OC, Rasmussen AB, Peacock TP, Sheppard CM, Barclay WS., Free PMC Article | 03/3/2023 |
| [Silenced ANP32A inhibits the growth, invasion and migration of colorectal cancer in vitro via the inactivation of AKT pathway]. | [Silenced ANP32A inhibits the growth, invasion and migration of colorectal cancer in vitro via the inactivation of AKT pathway].
Ding H, Li X, Zhou L, Cui Z, Meng H, Wang J., Free PMC Article | 03/3/2023 |
| AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation. | AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Wei R, Zhu Y, Zhang Y, Zhao W, Yu X, Wang L, Gu C, Gu X, Yang Y., Free PMC Article | 11/19/2022 |
| KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity. | KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity.
Yu M, Sun L, Zhang Z, Zhang Y, Zhang H, Na L, Wang X., Free PMC Article | 03/19/2022 |
| ANP32A promotes the proliferation, migration and invasion of hepatocellular carcinoma by modulating the HMGA1/STAT3 pathway. | ANP32A promotes the proliferation, migration and invasion of hepatocellular carcinoma by modulating the HMGA1/STAT3 pathway.
Tian Z, Liu Z, Fang X, Cao K, Zhang B, Wu R, Wen X, Wen Q, Shi H, Wang R. | 06/26/2021 |
| Host ANP32A mediates the assembly of the influenza virus replicase. | Host ANP32A mediates the assembly of the influenza virus replicase.
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM., Free PMC Article | 04/3/2021 |
| Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A. | Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A.
Camacho-Zarco AR, Kalayil S, Maurin D, Salvi N, Delaforge E, Milles S, Jensen MR, Hart DJ, Cusack S, Blackledge M., Free PMC Article | 09/12/2020 |
| Avian ANP32A proteins harbor an additional 33 amino acids compared to human ANP32A proteins, which are crucial for their ability to support the avian-origin influenza virus polymerase. Species differences in ANP32A can restrict the host range of influenza virus. | Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A.
Mistry B, Long JS, Schreyer J, Staller E, Sanchez-David RY, Barclay WS., Free PMC Article | 07/25/2020 |
| ANP32A and ANP32B mediate the export of unspliced or partially spliced viral mRNA via interactions with Rev and CRM1. | ANP32A and ANP32B are key factors in the Rev-dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA.
Wang Y, Zhang H, Na L, Du C, Zhang Z, Zheng YH, Wang X., Free PMC Article | 06/27/2020 |
| The contribution of minimal asparagine ladder from the leucine-rich repeat protein pp32 to stability is tested and lattice rigidity and hydrogen bond character is investigated. Point substitutions of the two ladder asparagines of pp32 are strongly destabilizing and decrease the cooperativity of unfolding. Asparagine side chains are held in a very rigid, nondynamic structure, making a significant contribution to stability. | A Second Backbone: The Contribution of a Buried Asparagine Ladder to the Global and Local Stability of a Leucine-Rich Repeat Protein.
Klein SA, Majumdar A, Barrick D., Free PMC Article | 06/27/2020 |
| ANP32A and ANP32B from different species are powerful factors in the maintenance of viral polymerase activity. Human ANP32A and ANP32B contribute equally to support human influenza viral RNA replication. | Fundamental Contribution and Host Range Determination of ANP32A and ANP32B in Influenza A Virus Polymerase Activity.
Zhang H, Zhang Z, Wang Y, Wang M, Wang X, Zhang X, Ji S, Du C, Chen H, Wang X., Free PMC Article | 05/30/2020 |
| Human ANP32A and ANP32B homologues both support function of human-adapted influenza polymerase but do not support efficient activity of avian IAV polymerase which requires avian ANP32A. | Species specific differences in use of ANP32 proteins by influenza A virus.
Long JS, Idoko-Akoh A, Mistry B, Goldhill D, Staller E, Schreyer J, Ross C, Goodbourn S, Shelton H, Skinner MA, Sang H, McGrew MJ, Barclay W., Free PMC Article | 02/29/2020 |
| ANP32A differentially regulates vRNA levels for species-specific effects on PB2 627E polymerase activity. | Insights into species-specific regulation of ANP32A on the mammalian-restricted influenza virus polymerase activity.
Bi Z, Ye H, Wang X, Fang A, Yu T, Yan L, Zhou J., Free PMC Article | 01/18/2020 |
| PHAP1 expression is elevated in glioma patients, which may accelerate the proliferation of glioma cells by regulating the Akt/p27/stathmin pathway. | PHAP1 promotes glioma cell proliferation by regulating the Akt/p27/stathmin pathway.
Xie M, Ji Z, Bao Y, Zhu Y, Xu Y, Wang L, Gao S, Liu Z, Tian Z, Meng Q, Shi H, Yu R., Free PMC Article | 12/14/2019 |
| ANP32A/ATM axis discovered in cartilage is also present in brain and bone. | ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.
Cornelis FMF, Monteagudo S, Guns LKA, den Hollander W, Nelissen RGHH, Storms L, Peeters T, Jonkers I, Meulenbelt I, Lories RJ. | 10/12/2019 |
| our data indicate that ANP32A is a novel regulator of histone H3 acetylation and promotes leukemogenesis. | ANP32A regulates histone H3 acetylation and promotes leukemogenesis.
Yang X, Lu B, Sun X, Han C, Fu C, Xu K, Wang M, Li D, Chen Z, Opal P, Wen Q, Crispino JD, Wang QF, Huang Z. | 04/20/2019 |
| The C-terminal portion of ANP32A and the middle domains (residues 307-534) of PB2 were required for PB2-ANP32A interaction. | The interaction of cellular protein ANP32A with influenza A virus polymerase component PB2 promotes vRNA synthesis.
Wei X, Liu Z, Wang J, Yang R, Yang J, Guo Y, Tan H, Chen H, Liu Q, Liu L. | 03/9/2019 |
| our study reveals that ANP32A dysregulation may be a critical factor contributing to acute megakaryoblastic leukemia | ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia.
Sun X, Lu B, Han C, Qiu W, Jin Q, Li D, Li Q, Yang Q, Wen Q, Opal P, Kini AR, Crispino JD, Huang Z., Free PMC Article | 09/1/2018 |
| These data suggest compensatory mechanisms underlying viral Polymerase adaptation to host ANP32A independent of species-specific interactions. | Functional Insights into ANP32A-Dependent Influenza A Virus Polymerase Host Restriction.
Domingues P, Hale BG., Free PMC Article | 05/19/2018 |
| ANP32A promoted CRC proliferation by inhibition of p38. | ANP32A modulates cell growth by regulating p38 and Akt activity in colorectal cancer.
Yan W, Bai Z, Wang J, Li X, Chi B, Chen X. | 04/28/2018 |
| Data show that PP32 and SET/TAF-Ibeta proteins block HAT1-mediated H4 acetylation. | PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4.
Saavedra F, Rivera C, Rivas E, Merino P, Garrido D, Hernández S, Forné I, Vassias I, Gurard-Levin ZA, Alfaro IE, Imhof A, Almouzni G, Loyola A., Free PMC Article | 12/16/2017 |
| Results suggest that ANP32A is commonly increased in oral squamous cell carcinoma and ANP32A protein could act as a potential biomarker for prognosis assessment of oral cancer patients with lymph node metastasis. | Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) association with lymph node metastasis predicts poor survival in oral squamous cell carcinoma patients.
Velmurugan BK, Yeh KT, Lee CH, Lin SH, Chin MC, Chiang SL, Wang ZH, Hua CH, Tsai MH, Chang JG, Ko YC., Free PMC Article | 12/2/2017 |
| According to the cellular function of the characterized targets of ProTalpha, and the evolution in the composition of the diverse ProTalpha-complexes when proliferation activity was reduced or apoptosis induced, leads to hypothesized that ProTalpha interactions might be related to the proliferation activity and control of the cell survival. | Prothymosin α interacts with SET, ANP32A and ANP32B and other cytoplasmic and mitochondrial proteins in proliferating cells.
Barbeito P, Sarandeses CS, Díaz-Jullien C, Muras J, Covelo G, Moreira D, Freire-Cobo C, Freire M. | 12/2/2017 |