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    TRIM11 tripartite motif containing 11 [ Homo sapiens (human) ]

    Gene ID: 81559, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Tripartite Motif-containing Protein 11 Silencing Inhibits Proliferation and Glycolysis and Promotes Apoptosis of Esophageal Squamous Cell Carcinoma Cells by Inactivating Signal Transduction and Activation of Transcription Factor 3/c-Myc Signaling.

    Tripartite Motif-containing Protein 11 Silencing Inhibits Proliferation and Glycolysis and Promotes Apoptosis of Esophageal Squamous Cell Carcinoma Cells by Inactivating Signal Transduction and Activation of Transcription Factor 3/c-Myc Signaling.
    Xuan T.

    09/3/2024
    TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2.

    TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2.
    Yu T, Yang X, Fu Q, Liang J, Wu X, Sheng J, Chen Y, Xiao L, Wu Y, Nie D, You X, Mai H, Chen K, Hu S.

    12/5/2023
    TRIM11 promotes cell proliferation of non-small cell lung cancer through the inhibition of ferroptosis by AMPK.

    TRIM11 promotes cell proliferation of non-small cell lung cancer through the inhibition of ferroptosis by AMPK.
    Liang Z, Li J, Zhang G, Chen M., Free PMC Article

    10/4/2023
    TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.

    TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
    Zhang ZY, Harischandra DS, Wang R, Ghaisas S, Zhao JY, McMonagle TP, Zhu G, Lacuarta KD, Song J, Trojanowski JQ, Xu H, Lee VM, Yang X., Free PMC Article

    08/7/2023
    TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.

    TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.
    Pan Y, Yu H, Lu F., Free PMC Article

    06/2/2023
    TRIM11, a new target of p53, facilitates the migration and invasion of nasopharyngeal carcinoma cells.

    TRIM11, a new target of p53, facilitates the migration and invasion of nasopharyngeal carcinoma cells.
    Zhao Z, Deng J, Lu M, Yang J, Chen L, Li D, Sang Y., Free PMC Article

    02/4/2023
    Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Translocation : An Emerging Entity Analyzed in a Series of 41 Cases.

    Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Translocation : An Emerging Entity Analyzed in a Series of 41 Cases.
    Hanna J, Ko JS, Billings SD, Boivin F, Beaudoux O, Pissaloux D, Tirode F, Laga A, Fletcher CDM, de la Fouchardiere A.

    10/22/2022
    Tripartite motif-containing protein 11 promotes hepatocellular carcinogenesis through ubiquitin-proteasome-mediated degradation of pleckstrin homology domain leucine-rich repeats protein phosphatase 1.

    Tripartite motif-containing protein 11 promotes hepatocellular carcinogenesis through ubiquitin-proteasome-mediated degradation of pleckstrin homology domain leucine-rich repeats protein phosphatase 1.
    Yang J, Ye J, Ma T, Tang F, Huang L, Liu Z, Tian S, Cheng X, Zhang L, Guo Z, Tu F, He M, Xu X, Lu X, Wu Y, Zeng X, Zou J, Wang X, Peng W, Zhang P.

    08/20/2022
    Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/beta-catenin signaling pathway.

    Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
    Jin X, Shao X, Pang W, Wang Z, Huang J., Free PMC Article

    06/11/2022
    Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.

    Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.
    He F, Wu Z, Wang Y, Yin L, Lu S, Dai L., Free PMC Article

    03/19/2022
    Tripartite motif protein 11 (TRIM11), an oncogene for human lung cancer via the DUSP6-mediated ERK1/2 signaling pathway.

    Tripartite motif protein 11 (TRIM11), an oncogene for human lung cancer via the DUSP6-mediated ERK1/2 signaling pathway.
    Wang XL, Lu SC, Sun C, Jin WG, Fan YW, Shu YS, Shi HC, Min LF., Free PMC Article

    01/22/2022
    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease.

    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease.
    Zhu G, Harischandra DS, Ghaisas S, Zhang P, Prall W, Huang L, Maghames C, Guo L, Luna E, Mack KL, Torrente MP, Luk KC, Shorter J, Yang X., Free PMC Article

    12/18/2021
    miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.

    miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
    Song Z, Guo Q, Wang H, Gao L, Wang S, Liu D, Liu J, Qi Y, Lin B.

    08/28/2021
    Knockdown of TRIM5alpha or TRIM11 increases lentiviral vector transduction efficiency of human Muller cells.

    Knockdown of TRIM5α or TRIM11 increases lentiviral vector transduction efficiency of human Muller cells.
    Sauter MM, Brandt CR., Free PMC Article

    08/28/2021
    TRIM11 stimulates the proliferation of gastric cancer through targeting CPEB3/EGFR axis.

    TRIM11 stimulates the proliferation of gastric cancer through targeting CPEB3/EGFR axis.
    Luo N, Wang Z.

    07/24/2021
    Association of Tripartite Motif Containing 11 rs564309 With Tau Pathology in Progressive Supranuclear Palsy.

    Association of Tripartite Motif Containing 11 rs564309 With Tau Pathology in Progressive Supranuclear Palsy.
    Valentino RR, Koga S, Heckman MG, Brushaber DE, Diehl NN, Walton RL, Dickson DW, Ross OA., Free PMC Article

    05/8/2021
    TRIM11 promotes lymphomas by activating the beta-catenin signaling and Axin1 ubiquitination degradation.

    TRIM11 promotes lymphomas by activating the β-catenin signaling and Axin1 ubiquitination degradation.
    Hou Y, Ding M, Wang C, Yang X, Ye T, Yu H.

    10/31/2020
    TRIM11 might suppress the translation of DUSP6 via improving its ubiquitination. Additionally, TRIM11 silencing in osteosarcoma (OS) cells significantly reduced its tumorigenicity in vivo.

    Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.
    Wang Z, Xu X, Tang W, Zhu Y, Hu J, Zhang X., Free PMC Article

    07/4/2020
    During these processes, TRIM11 interacts with and stabilizes HSF1, increaseing HSF1 levels in the nucleus. These findings identify that TRIM11, through cooperation with HSF1, protects cells against the proteotoxic stress and promotes tumor cell survival.

    TRIM11 cooperates with HSF1 to suppress the anti-tumor effect of proteotoxic stress drugs.
    Chen L, Yang X., Free PMC Article

    02/22/2020
    TRIM11 locus is a genetic modifier of progressive supranuclear palsy phenotype.

    Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype.
    Jabbari E, Woodside J, Tan MMX, Shoai M, Pittman A, Ferrari R, Mok KY, Zhang D, Reynolds RH, de Silva R, Grimm MJ, Respondek G, Müller U, Al-Sarraj S, Gentleman SM, Lees AJ, Warner TT, Hardy J, Revesz T, Höglinger GU, Holton JL, Ryten M, Morris HR., Free PMC Article

    08/24/2019
    Study detected high expression levels of TRIM11 in breast cancer tissues. Downregulation of TRIM11 in MCF7 and MDAMB231 cells inhibited cell proliferation and promoted cell apoptosis.

    Tripartite motif‑containing 11 regulates the proliferation and apoptosis of breast cancer cells.
    Dai X, Geng F, Li M, Liu M.

    06/29/2019
    CRTC1-TRIM11 fusion appears to be specific of an unpigmented nodular tumor combining a melanocytic phenotype and low-grade tumor behavior.

    Cutaneous Melanocytoma With CRTC1-TRIM11 Fusion: Report of 5 Cases Resembling Clear Cell Sarcoma.
    Cellier L, Perron E, Pissaloux D, Karanian M, Haddad V, Alberti L, de la Fouchardière A.

    03/16/2019
    TRIM11 was upregulated in prostate cancer tissue and was associated with reduced prognosis. TRIM11 expression increased cell proliferation in vitro and was downregulated by miR-5193.

    Expression of Tripartite Motif-Containing Proteactiin 11 (TRIM11) is Associated with the Progression of Human Prostate Cancer and is Downregulated by MicroRNA-5193.
    Pan Y, Zhang R, Chen H, Chen W, Wu K, Lv J., Free PMC Article

    03/9/2019
    findings identify TRIM11 as an important activator of the proteasome, define a pathway that adjusts proteasome activity, and reveal a mechanism by which tumor cells acquire higher degradative power to support oncogenic growth

    TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.
    Chen L, Zhu G, Johns EM, Yang X., Free PMC Article

    12/22/2018
    Data show that miR-24-3p downregulation contributes to tripartite motif-containing protein 11 (TRIM11) upregulation in cancer (CC).

    TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer.
    Yin Y, Zhong J, Li SW, Li JZ, Zhou M, Chen Y, Sang Y, Liu L., Free PMC Article

    03/10/2018
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