| <i>DEFB126</i> polymorphisms and association with idiopathic asthenozoospermia in China. | DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China.
He JY, Peng JY, Li QF, Lin XL, Cui YR, Ma SY, Fan SY, Liu YR, Song ZL, Deng JH, Wei X, Ding XP., Free PMC Article | 11/19/2022 |
| Beta-defensin126 is correlated with sperm motility in fertile and infertile mendagger. | Beta-defensin126 is correlated with sperm motility in fertile and infertile men†.
Aram R, Chan PTK, Cyr DG. | 06/12/2021 |
| The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome. | The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome.
Boroujeni PB, Ebrahimian S, Abedini M, Chayjan MR, Hassani M, Gourabi H, Sadighi-Gilani MA, Sabbaghian M, Meybodi AM. | 08/22/2020 |
| It is a immune component extensively expressed in mucosa and epidermis, which are responsible for the first line of host defense. | Influence of chewing on expression level of human beta-defensin 2 and secretory immunoglobulin A in the epithelium.
Ishida A, Wada T, Ogami K, Ueda T, Sakurai K. | 08/10/2019 |
| Data indicate a significant contribution of the frame-shift polymorphism of defensin beta 126 (DEFB126) rs11467497 to male infertility. | Another functional frame-shift polymorphism of DEFB126 (rs11467497) associated with male infertility.
Duan S, Shi C, Chen G, Zheng JF, Wu B, Diao H, Ji L, Gu Y, Xin A, Wu Y, Zhou W, Miao M, Xu L, Li Z, Yuan Y, Wang P, Shi H., Free PMC Article | 04/2/2016 |
| These results demonstrate that the DEFB126 core peptide has critical functions in parallel to its C-terminal tail by showing LPS-binding activity, anti-inflammatory effects and intracellular regulatory function. In addition, DEFB126 displays antimicrobial activity against E. coli, S. aureus, and C. elegans. | Human beta-defensin DEFB126 is capable of inhibiting LPS-mediated inflammation.
Liu H, Yu H, Gu Y, Xin A, Zhang Y, Diao H, Lin D. | 11/5/2014 |
| This review shows how DEFB126 is critical for efficient transport of sperm in the female reproductive tract, preventing their recognition by the female immune system. | Multifunctional glycoprotein DEFB126--a curious story of defensin-clad spermatozoa.
Tollner TL, Bevins CL, Cherr GN. | 05/25/2013 |
| DEFB126 genotype and lectin binding were correlated with sperm performance in the penetration assays. | A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility.
Tollner TL, Venners SA, Hollox EJ, Yudin AI, Liu X, Tang G, Xing H, Kays RJ, Lau T, Overstreet JW, Xu X, Bevins CL, Cherr GN., Free PMC Article | 01/14/2012 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Polymorphisms in innate immunity genes and risk of childhood leukemia.
Han S, Lan Q, Park AK, Lee KM, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Ahn YO, Chanock SJ, Kim H, Rothman N, Kang D., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesRisk of meningioma and common variation in genes related to innate immunity.
Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD. Common variation in genes related to innate immunity and risk of adult glioma.
Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ, Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ. | 06/30/2010 |
| Analyses restricted to glioblastoma (n = 254) yielded significant associations for the SELP, DEFB126/127, SERPINI1, and LY96 genetic regions. | Common variation in genes related to innate immunity and risk of adult glioma.
Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ, Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ., Free PMC Articles: PMC2771723, PMC2771723 | 01/21/2010 |