| NETO2 promotes melanoma progression via activation of the Ca[2+]/CaMKII signaling pathway. | NETO2 promotes melanoma progression via activation of the Ca(2+)/CaMKII signaling pathway.
Zhu S, Zhang X, Guo Y, Tang L, Zhou Z, Chen X, Peng C. | 06/2/2023 |
| Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth. | Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.
Li Y, Wang W, Hou X, Huang W, Zhang P, He Y, Wang B, Duan Q, Mao F, Guo D., Free PMC Article | 01/21/2023 |
| Kainate receptor modulation by NETO2. | Kainate receptor modulation by NETO2.
He L, Sun J, Gao Y, Li B, Wang Y, Dong Y, An W, Li H, Yang B, Ge Y, Zhang XC, Shi YS, Zhao Y. | 02/5/2022 |
| NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway. | NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway.
Xu JC, Chen TY, Liao LT, Chen T, Li QL, Xu JX, Hu JW, Zhou PH, Zhang YQ., Free PMC Article | 01/8/2022 |
| Neuropilin and tolloid-like 2 regulates the progression of osteosarcoma. | Neuropilin and tolloid-like 2 regulates the progression of osteosarcoma.
Wang X, Bian Z, Hou C, Li M, Jiang W, Zhu L. | 01/23/2021 |
| NETO2 expression is up-regulated in Nasopharyngeal carcinoma (NPC) clinical specimens and cell lines. NETO2 down-regulation reduces proliferation, migration and invasion in irradiated NPC cell lines. | Reducing NETO2 expression prevents human nasopharyngeal carcinoma (NPC) progression by suppressing metastasis and inducing apoptosis.
He AR, Zhu Q, Gao S. | 05/2/2020 |
| NETO2 promotes invasion and metastasis of gastric cancer cells and represents a novel prognostic indicator as well as a potential therapeutic target in gastric cancer. | NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-ÎșB/Snail axis and predicts outcome of the patients.
Liu JY, Jiang L, He T, Liu JJ, Fan JY, Xu XH, Tang B, Shi Y, Zhao YL, Qian F, Wang Y, Cui YH, Yu PW., Free PMC Article | 04/11/2020 |
| upregulation of NETO2 gene is first stipulated by the isoform 1 (NM_018092.4), and the probable mechanism of its activation is associated with the increased expression of SAP30 transcription factor. | [Transcription Factor SAP30 Is Involved in the Activation of NETO2 Gene Expression in Clear Cell Renal Cell Carcinoma].
Snezhkina AV, Nyushko KM, Zaretsky AR, Shagin DA, Sadritdinova AF, Fedorova MS, Guvatova ZG, Abramov IS, Pudova EA, Alekseev BY, Dmitriev AA, Kudryavtseva AV. | 12/22/2018 |
| NETO2 may be involved in colorectal cancer progression, but is not directly associated with epithelial-mesenchymal transition | Upregulation of NETO2 gene in colorectal cancer.
Fedorova MS, Snezhkina AV, Pudova EA, Abramov IS, Lipatova AV, Kharitonov SL, Sadritdinova AF, Nyushko KM, Klimina KM, Belyakov MM, Slavnova EN, Melnikova NV, Chernichenko MA, Sidorov DV, Kiseleva MV, Kaprin AD, Alekseev BY, Dmitriev AA, Kudryavtseva AV., Free PMC Article | 12/22/2018 |
| Results suggested that the extracellular N-terminal region including the two CUB domains was largely responsible for the distinct regulatory effects of Neto1 and Neto2 on the desensitization properties of GluK1 homomeric receptors | The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors.
Fisher JL., Free PMC Article | 09/3/2016 |
| NETO2 upregulation could serve as a potential biomarker for the prediction of advanced tumor progression and unfavorable prognosis in patients with colorectal carcinoma. | Upregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma.
Hu L, Chen HY, Cai J, Yang GZ, Feng D, Zhai YX, Gong H, Qi CY, Zhang Y, Fu H, Cai QP, Gao CF., Free PMC Article | 08/13/2016 |
| Determination of the neuropilin and tolloid-like protein 2 signal peptide cleavage site by N-terminal sequencing. | Signal peptide prediction based on analysis of experimentally verified cleavage sites.
Zhang Z, Henzel WJ., Free PMC Article | 01/24/2011 |
| Rat neto2 plays a role in glutamate signaling in the brain by modulating the function of kainate receptors. | A transmembrane accessory subunit that modulates kainate-type glutamate receptors.
Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S., Free PMC Article | 01/21/2011 |