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    CASP3 caspase 3 [ Homo sapiens (human) ]

    Gene ID: 836, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    HIV-1 Vpu induces neurotoxicity by promoting Caspase 3-dependent cleavage of TDP-43.

    HIV-1 Vpu induces neurotoxicity by promoting Caspase 3-dependent cleavage of TDP-43.
    Yang J, Li Y, Li H, Zhang H, Guo H, Zheng X, Yu XF, Wei W., Free PMC Article

    10/18/2024
    Neutrophil Extracellular Traps Induce Pyroptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the NF-kappaB/Caspase 3/GSDME Pathway.

    Neutrophil Extracellular Traps Induce Pyroptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the NF-κB/Caspase 3/GSDME Pathway.
    Mao J, Tan M, Li J, Liu C, Hao J, Zheng J, Shen H.

    10/7/2024
    PPARgamma regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.

    PPARγ regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.
    Yuan H, Yi N, Li D, Xu C, Yin GR, Zhuang C, Wang YJ, Ni S., Free PMC Article

    08/15/2024
    A Non-Apoptotic Pattern of Caspase-9/Caspase-3 Activation During Differentiation of Human Embryonic Stem Cells into Cardiomyocytes.

    A Non-Apoptotic Pattern of Caspase-9/Caspase-3 Activation During Differentiation of Human Embryonic Stem Cells into Cardiomyocytes.
    Ghorbani N, Shiri M, Alian M, Yaghubi R, Shafaghi M, Hojjat H, Pahlavan S, Davoodi J.

    06/28/2024
    Decreasing circ_0014614 promotes the differentiation of bone marrow flineage cells into megakaryocytes in essential thrombocythemia via activiation of miR-138-5p/caspase3 axis.

    Decreasing circ_0014614 promotes the differentiation of bone marrow flineage cells into megakaryocytes in essential thrombocythemia via activiation of miR-138-5p/caspase3 axis.
    Yu G, Chen X, Lu W, Li Y, Chen Y, Yin C, Zheng Z, Huang X, Xu D.

    06/12/2024
    A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells.

    A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells.
    Niedermeyer S, Yun X, Trujillo M, Jiang H, Andrade MR, Kolb TM, Suresh K, Damarla M, Shimoda LA.,

    05/23/2024
    MiR-98-5p plays suppressive effects on IL-1beta-induced chondrocyte injury associated with osteoarthritis by targeting CASP3.

    MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3.
    Lv H, Liu P, Hu H, Li X, Li P., Free PMC Article

    04/19/2024
    Expression and Clinical Significance of IRE1-XBP1s, p62, and Caspase-3 in Colorectal Cancer Patients.

    Expression and Clinical Significance of IRE1-XBP1s, p62, and Caspase-3 in Colorectal Cancer Patients.
    Zarafshani M, Mahmoodzadeh H, Soleimani V, Moosavi MA, Rahmati M., Free PMC Article

    03/12/2024
    CASP3 gene expression and the role of caspase 3 in the pathogenesis of depressive disorders.

    CASP3 gene expression and the role of caspase 3 in the pathogenesis of depressive disorders.
    Bliźniewska-Kowalska K, Gałecki P, Szemraj J, Su KP, Chang JP, Gałecka M., Free PMC Article

    09/8/2023
    Evaluation of the Expression of miRNAs, LncRNAs, and their Target Gene, Caspase 3 in Glioblastoma Multiform: A Case-Control Study.

    Evaluation of the Expression of miRNAs, LncRNAs, and their Target Gene, Caspase 3 in Glioblastoma Multiform: A Case-Control Study.
    Haghighi SS, Ghaderian SMH, Rakhshan A, Motamed N.

    08/23/2023
    In-Depth Characterization of Apoptosis N-Terminome Reveals a Link Between Caspase-3 Cleavage and Posttranslational N-Terminal Acetylation.

    In-Depth Characterization of Apoptosis N-Terminome Reveals a Link Between Caspase-3 Cleavage and Posttranslational N-Terminal Acetylation.
    Hanna R, Rozenberg A, Saied L, Ben-Yosef D, Lavy T, Kleifeld O., Free PMC Article

    07/26/2023
    Caspase-3 in glioma indicates an unfavorable prognosis by involving surrounding angiogenesis and tumor cell repopulation.

    Caspase-3 in glioma indicates an unfavorable prognosis by involving surrounding angiogenesis and tumor cell repopulation.
    Feng X, Zhu F, Dai L, Liu X, Shao L, Hao L, Cang S, Cheng J.

    07/12/2023
    [Overexpression of miR-431-5p impairs mitochondrial function and induces apoptosis in gastric cancer cells via the Bax/Bcl-2/caspase3 pathway].

    [Overexpression of miR-431-5p impairs mitochondrial function and induces apoptosis in gastric cancer cells via the Bax/Bcl-2/caspase3 pathway].
    Wu J, Deng Z, Zhu Y, Dou G, Li J, Huang L., Free PMC Article

    05/23/2023
    Central Centrifugal Cicatricial Alopecia Associated With PDL1 Loss and Increased Expression of Caspase 3: A Case Series.

    Central Centrifugal Cicatricial Alopecia Associated With PDL1 Loss and Increased Expression of Caspase 3: A Case Series.
    Smith SDB, Woddor N, Cassarino DS, Chen W, Clemetson N, Nava VE.

    05/19/2023
    Traumatic Brain Injury Induces Microglial and Caspase3 Activation in the Retina.

    Traumatic Brain Injury Induces Microglial and Caspase3 Activation in the Retina.
    Kovács-Öller T, Zempléni R, Balogh B, Szarka G, Fazekas B, Tengölics ÁJ, Amrein K, Czeiter E, Hernádi I, Büki A, Völgyi B., Free PMC Article

    03/27/2023
    Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis.

    Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis.
    Lai Y, Li X, Li T, Li X, Nyunoya T, Chen K, Kitsios G, Nouraie M, Zhang Y, McVerry BJ, Lee JS, Mallmapalli RK, Zou C., Free PMC Article

    03/20/2023
    Caspase-3, Caspase-8 and XIAP Gene Expression in the Placenta: Exploring the Causes of Spontaneous Preterm Labour.

    Caspase-3, Caspase-8 and XIAP Gene Expression in the Placenta: Exploring the Causes of Spontaneous Preterm Labour.
    Belousova V, Svitich O, Timokhina E, Ignatko I, Bogomazova I, Pesegova S, Silaeva T, Kuzmina T, Skorobogatova O., Free PMC Article

    02/4/2023
    Caspase 3 and Cleaved Caspase 3 Expression in Tumorogenesis and Its Correlations with Prognosis in Head and Neck Cancer: A Systematic Review and Meta-Analysis.

    Caspase 3 and Cleaved Caspase 3 Expression in Tumorogenesis and Its Correlations with Prognosis in Head and Neck Cancer: A Systematic Review and Meta-Analysis.
    Silva FFVE, Padín-Iruegas ME, Caponio VCA, Lorenzo-Pouso AI, Saavedra-Nieves P, Chamorro-Petronacci CM, Suaréz-Peñaranda J, Pérez-Sayáns M., Free PMC Article

    10/22/2022
    Expression levels of caspase-3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer.

    Expression levels of caspase-3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer.
    Huang YL, Zhang GH, Zhu Q, Wu X, Wu LG., Free PMC Article

    09/24/2022
    Caspase-3-Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma.

    Caspase-3-Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma.
    Mok EHK, Leung CON, Zhou L, Lei MML, Leung HW, Tong M, Wong TL, Lau EYT, Ng IOL, Ding J, Yun JP, Yu J, Zhu HL, Lin CH, Lindholm D, Leung KS, Cybulski JD, Baker DM, Ma S, Lee TKW.

    09/17/2022
    Association of the CASP3 rs4647602 Gene Polymorphism with Periodontitis in South Indians of Tamil Ethnicity.

    Association of the CASP3 rs4647602 Gene Polymorphism with Periodontitis in South Indians of Tamil Ethnicity.
    Loka AM, Ponnaiyan D, Parthasarathy H, Tadepalli A, Victor DJ.

    09/3/2022
    The evaluation of both the expression and serum protein levels of Caspase-3 gene in patients with different degrees of SARS-CoV2 infection.

    The evaluation of both the expression and serum protein levels of Caspase-3 gene in patients with different degrees of SARS-CoV2 infection.
    Yildiz Gulhan P, Eroz R, Ataoglu O, İnce N, Davran F, Öztürk CE, Gamsızkan Z, Balbay OA., Free PMC Article

    06/18/2022
    Lobaplatin Induces Pyroptosis in Cervical Cancer Cells via the Caspase-3/GSDME Pathway.

    Lobaplatin Induces Pyroptosis in Cervical Cancer Cells via the Caspase-3/GSDME Pathway.
    Chen J, Ge L, Shi X, Liu J, Ruan H, Heng D, Ye C.

    05/28/2022
    Placental apoptotic markers are associated with placental morphometry.

    Placental apoptotic markers are associated with placental morphometry.
    Kasture V, Sundrani D, Randhir K, Wagh G, Joshi S.

    03/5/2022
    Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway.

    Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway.
    Zhang Z, Zhang H, Li D, Zhou X, Qin Q, Zhang Q., Free PMC Article

    02/19/2022
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