| Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains. | Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains.
Masutani M, Sakurai S, Shimizu T, Ohto U. | 05/15/2021 |
| Role of the Glycosylphosphatidylinositol-Anchored Protein TEX101 and Its Related Molecules in Spermatogenesis. | Role of the Glycosylphosphatidylinositol-Anchored Protein TEX101 and Its Related Molecules in Spermatogenesis.
Yoshitake H, Araki Y., Free PMC Article | 03/6/2021 |
| Study provides evidence that spermatozoa of rs35033974 homozygous men have substantially reduced levels of TEX101 and could be used as a model to elucidate the precise TEX101 function. Because TEX101 seminal plasma levels were found significantly lower in heterozygous than in WT men, rs35033974 status could be considered in TEX101 diagnostics. | Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974.
Schiza C, Korbakis D, Jarvi K, Diamandis EP, Drabovich AP., Free PMC Article | 11/30/2019 |
| Overexpression of TEX101 is associated with breast tumors. | Transcriptome analysis of the cancer/testis genes, DAZ1, AURKC, and TEX101, in breast tumors and six breast cancer cell lines.
Mobasheri MB, Shirkoohi R, Zendehdel K, Jahanzad I, Talebi S, Afsharpad M, Modarressi MH. | 01/30/2016 |
| Clinical assays for ECM1 and TEX101 have the potential to replace most of the diagnostic testicular biopsies and facilitate the prediction of outcome of sperm retrieval procedures, increasing the reliability and success of assisted reproduction techniques | Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma.
Drabovich AP, Dimitromanolakis A, Saraon P, Soosaipillai A, Batruch I, Mullen B, Jarvi K, Diamandis EP. | 07/12/2014 |
| TEX101 is a cancer-testis (CT) gene useful for detection of CML. It was expressed in 30% of CML patients, but not in healthy donors. Unlike many CT genes, overexpression of TEX101 was not shown to induce immunologic responses in these samples. | Expression of testis-specific genes, TEX101 and ODF4, in chronic myeloid leukemia and evaluation of TEX101 immunogenicity.
Ghafouri-Fard S, Modarressi MH, Yazarloo F., Free PMC Article | 10/20/2012 |
| Combination of two proteins, SPAG11B and TEX101, can be used for differential diagnosis of azoospermia | Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay.
Drabovich AP, Jarvi K, Diamandis EP., Free PMC Article | 04/7/2012 |
| Overexpression of NYD-SP8 in various nasopharyngeal carcinoma cell lines indicated its complicated functions, and that it could play an important role in nasopharyngeal carcinoma carcinogenesis. | Preparation of anti-NYD-SP8 rabbit polyclonal antibody and its application in the analysis of NYD-SP8 expression in nasopharyngeal carcinoma cell lines and clinical tissues.
Yang LL, Wu JB, Liu ZG, U L, Zeng MS, Yan SS, Chan HC, Xia YF. | 04/7/2012 |
| NYD-SP8 has a role in regulating ECM degradation, providing a novel mechanism that modulates urokinase signalling in the suppression of cancer progression | A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis.
Yin LL, Chung CM, Chen J, Fok KL, Ng CP, Jia RR, Ren X, Zhou J, Zhang T, Zhao XH, Lin M, Zhu H, Zhang XH, Tsang LL, Bi Y, Zhou Z, Mo F, Wong N, Chung YW, Sha J, Chan HC., Free PMC Article | 12/24/2011 |
| The SPATA19 and TEX101 genes may be possible targets for cancer immunotherapy and novel markers for early detection of basal cell carcinoma. | Elevated expression levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features.
Ghafouri-Fard S, Abbasi A, Moslehi H, Faramarzi N, Taba Taba Vakili S, Mobasheri MB, Modarressi MH. | 10/23/2010 |
| identification & function of a novel sperm GPI-anchored membrane protein, NYD-SP8; release of NYD-SP8 during sperm-egg interaction & binding to cumulus elicits cross-talk between the gametes leading to the acrosome reaction | A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction.
Yin L, Chung CM, Huo R, Liu H, Zhou C, Xu W, Zhu H, Zhang J, Shi Q, Wong HY, Chen J, Lu Y, Bi Y, Zhao C, Du Y, Ma M, Cai Y, Chen WY, Fok KL, Tsang LL, Li K, Ni Y, Chung YW, Zhou Z, Sha J, Chan HC., Free PMC Article | 01/21/2010 |