| Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways. | Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways.
Wang W, Zhao Y, Zhu P, Jia X, Wang C, Zhang Q, Li H, Wang J, Hou Y. | 02/22/2024 |
| Associations of ANGPTL6, DOCK6, FABP1, and PCSK9 single-nucleotide variants with hypercholesterolemia in the Polish population: a cross-sectional study. | Associations of ANGPTL6, DOCK6, FABP1, and PCSK9 single-nucleotide variants with hypercholesterolemia in the Polish population: a cross-sectional study.
Świderska MK, Mostowska A, Skrypnik D, Bogdański P, Jagodziński PP, Grzegorzewska AE. | 03/1/2023 |
| Relationship of ANGPTL6 With Neonatal Glucose Homeostasis and Fat Mass Is Disrupted in Gestational Diabetic Pregnancies. | Relationship of ANGPTL6 With Neonatal Glucose Homeostasis and Fat Mass Is Disrupted in Gestational Diabetic Pregnancies.
Valencia-Martínez A, Schaefer-Graf U, Amusquivar E, Herrera E, Ortega-Senovilla H. | 10/8/2022 |
| Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker. | Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker.
Hu G, Gao F, Wang G, Fang Y, Guo Y, Zhou J, Gu Y, Zhang C, Gao N, Wen Q, Qiao H., Free PMC Article | 09/18/2021 |
| Angiopoietin-Like Growth Factor Involved in Leptin Signaling in the Hypothalamus. | Angiopoietin-Like Growth Factor Involved in Leptin Signaling in the Hypothalamus.
Jang Y, Heo JY, Lee MJ, Zhu J, Seo C, Go DH, Yoon SK, Yukari D, Oike Y, Sohn JW, Shong M, Kweon GR., Free PMC Article | 07/10/2021 |
| ANGPTL6 Genetic Variants Are an Underlying Cause of Familial Intracranial Aneurysms. | ANGPTL6 Genetic Variants Are an Underlying Cause of Familial Intracranial Aneurysms.
Hostettler IC, O'Callaghan B, Bugiardini E, O'Connor E, Vandrovcova J, Davagnanam I, Alg V, Bonner S, Walsh D, Bulters D, Kitchen N, Brown MM, Grieve J, Werring DJ, Houlden H, Genetics and Observational Subarachnoid Haemorrhage (GOSH) study investigators., Free PMC Article | 02/27/2021 |
| Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes. | Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes.
Qaddoumi MG, Alanbaei M, Hammad MM, Al Khairi I, Cherian P, Channanath A, Thanaraj TA, Al-Mulla F, Abu-Farha M, Abubaker J., Free PMC Article | 12/12/2020 |
| ANGPTL6 is an important driver gene of angiogenesis in AFPGC development | ANGPTL6-mediated angiogenesis promotes alpha fetoprotein-producing gastric cancer progression.
Chen E, Tang C, Peng K, Cheng X, Wei Y, Liu T. | 01/18/2020 |
| rare coding variants in ANGPTL6 are causally related to familial forms of Intracranial aneurysms. | Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm.
Bourcier R, Le Scouarnec S, Bonnaud S, Karakachoff M, Bourcereau E, Heurtebise-Chrétien S, Menguy C, Dina C, Simonet F, Moles A, Lenoble C, Lindenbaum P, Chatel S, Isidor B, Génin E, Deleuze JF, Schott JJ, Le Marec H, ICAN Study Group, Loirand G, Desal H, Redon R., Free PMC Article | 12/22/2018 |
| Poor glycemic control in diabetes mellitus as reflected by higher serum HbA1c levels is associated with raised serum ANGPTL6 levels | Correlation of long-term glycemic control as measured by glycated hemoglobin with serum angiopoietin-like 6 protein levels in type 2 diabetes mellitus patients.
Sharma V, Pangtey GS, Gupta R, Rehan HS, Gupta LK., Free PMC Article | 06/30/2018 |
| ANGPTL6, S100A8 and S100A9 are overexpressed in skin of psoriasis patients versus zero expression in controls. | Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.
Tanigawa H, Miyata K, Tian Z, Aoi J, Kadomatsu T, Fukushima S, Ogata A, Takeda N, Zhao J, Zhu S, Terada K, Endo M, Morinaga J, Sugizaki T, Sato M, Morioka MS, Manabe I, Mashimo Y, Hata A, Taketomi Y, Yamamoto K, Murakami M, Araki K, Jinnin M, Ihn H, Oike Y., Free PMC Article | 06/23/2018 |
| Data suggest that serum AGF levels are up-regulated in type 2 diabetic patients with lower extremity peripheral arterial disease according to disease severity; patients with highest serum AGF levels exhibit increased cardiovascular mortality and all-cause mortality. | Angiopoietin-related growth factor is independently associated with lower extremity peripheral arterial disease.
Nie H, Liang Y, Wang HX, Ren HL, Wang YW, Li FD, Zheng YH. | 03/3/2018 |
| Serum ANGPTL6 levels increased in patients with a hypothyroid status, and both TSH and free T4 levels are associated with ANGPLT6 levels, suggesting a possible association between thyroid function and ANGPTL6 levels. | Influence of thyroid dysfunction on serum levels of angiopoietin-like protein 6.
Lim JA, Kim HJ, Ahn HY, Park KU, Yi KH, Park DJ, Jang HC, Park YJ. | 01/2/2016 |
| AGF concentrations is significantly higher in patients with type 2 diabetes as compared to controls. | Relationship between serum levels of angiopoietin-related growth factor and metabolic risk factors.
Ebert T, Kralisch S, Loessner U, Jessnitzer B, Stumvoll M, Fasshauer M, Tönjes A. | 06/20/2015 |
| In the second trimester, Angptl6 levels are higher in women with subsequent pregnancy-induced hypertension. | Elevated serum angiopoietin-like protein 6 in women with subsequent pregnancy-induced hypertension: a preliminary study.
Tuuri AL, Jauhiainen MS, Ehnholm CP, Tikkanen MJ, Nicholls MG, Kaaja RJ. | 07/19/2014 |
| There are no significant differences in maternal Angptl6/ARP5 serum level between pre-eclamptic women and normally pregnant control women | Alterations of angiopoietin-related growth factor (Angptl6) during pregnancy and in pre-eclampsia.
Xia G, Fang M, He Y, Zhang T, Jin Y, Jiang L. | 04/26/2014 |
| Serum AGF levels are significantly higher in subjects with polycystic ovary syndrome than those in the healthy control group. | Serum levels of angiopoietin-related growth factor (AGF) are increased in polycystic ovary syndrome.
Boztosun A, Deveci K, Klçl F, Söylemez MS, Muhtaroğlu S, Müderris II. | 10/26/2013 |
| Interaction between alpha6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. | A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6.
Marchiò S, Soster M, Cardaci S, Muratore A, Bartolini A, Barone V, Ribero D, Monti M, Bovino P, Sun J, Giavazzi R, Asioli S, Cassoni P, Capussotti L, Pucci P, Bugatti A, Rusnati M, Pasqualini R, Arap W, Bussolino F., Free PMC Article | 06/8/2013 |
| ANGPTL6 affects resting metabolic rate (RMR), significantly improves lipid profile and slightly improves insulin levels and insulin sensitivity, as well. | Evidence of a role of ANGPTL6 in resting metabolic rate and its potential application in treatment of obesity.
Mirzaei K, Hossein-Nezhad A, Chamari M, Shahbazi S. | 08/20/2011 |
| serum AGF levels were paradoxically increased in metabolic syndrome, in comparison with data from animal experiments and data on sex, age, and waist circumference | Serum levels of angiopoietin-related growth factor are increased in metabolic syndrome.
Namkung J, Koh SB, Kong ID, Choi JW, Yeh BI. | 05/28/2011 |
| study of associations between ANGPTL6 polymorphisms and metabolic syndrome or related phenotypes in a French population | Association between angiopoietin-like 6 (ANGPTL6) gene polymorphisms and metabolic syndrome-related phenotypes in the French MONICA Study.
Legry V, Goumidi L, Huyvaert M, Cottel D, Ferrières J, Arveiler D, Bingham A, Wagner A, Ruidavets JB, Ducimetière P, Amouyel P, Meirhaeghe A. | 01/21/2010 |
| Our results strongly suggest that AGF is an integrin ligand as well as a mitogenic growth factor and theoretically participates in cutaneous wound healing in a more complex mechanism. | Angiopoietin-related growth factor (AGF) supports adhesion, spreading, and migration of keratinocytes, fibroblasts, and endothelial cells through interaction with RGD-binding integrins.
Zhang Y, Hu X, Tian R, Wei W, Hu W, Chen X, Han W, Chen H, Gong Y. | 01/21/2010 |
| findings suggest that AGF affects epidermal proliferation and thereby plays a role in the wound healing process | Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration.
Oike Y, Yasunaga K, Ito Y, Matsumoto S, Maekawa H, Morisada T, Arai F, Nakagata N, Takeya M, Masuho Y, Suda T., Free PMC Article | 01/21/2010 |
| showed that AGF is a secreted protein, AGF directly promotes chemotactic activity of vascular endothelial cells, and AGF directly induces a permeability change in the local vasculature. | Angiopoietin-related growth factor (AGF) promotes angiogenesis.
Oike Y, Ito Y, Maekawa H, Morisada T, Kubota Y, Akao M, Urano T, Yasunaga K, Suda T. | 01/21/2010 |