| Expression of Metalloproteinases and Type I and III Collagens during Healing of Excisional Skin Wound on the Abdomen and Back in Rats. | Expression of Metalloproteinases and Type I and III Collagens during Healing of Excisional Skin Wound on the Abdomen and Back in Rats.
Kananykhina EY, Shmakova TV, Bolshakova GB, Rusanov FS, Elchaninov AV, Nikitina MP, Lokhonina AV, Makarov AV, Fatkhudinov TK. | 03/20/2021 |
| the activation of Pin1 promoted cardiac extracellular matrix deposition and oxidative stress damage by regulating the phosphorylation of the MEK1/2ERK1/2 signaling pathway and the expression of alphaSMA. | Pin1 facilitates isoproterenol‑induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2‑ERK1/2 signal transduction pathway in rats.
Wu X, Li M, Chen SQ, Li S, Guo F., Free PMC Article | 08/4/2018 |
| the diagnostic value of urinary collagen degradation products in a proteinuria-driven fibrosis rat model, was investigated. | Urinary collagen degradation products as early markers of progressive renal fibrosis.
Hijmans RS, Rasmussen DG, Yazdani S, Navis G, van Goor H, Karsdal MA, Genovese F, van den Born J., Free PMC Article | 11/4/2017 |
| miR-let-7b and COL3A1 might play critical roles in neuronal injury, they are potential therapeutic targets. | Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b.
Wang Q, She Y, Bi X, Zhao B, Ruan X, Tan Y. | 09/23/2017 |
| Data show that collagen type III (Col3), collagen type IV (Col4) and p38 mitogen-activated protein kinase (p38 MAPK) are up-regulated in models of diabetic nephropathy. | [Down-regulation of p38 MAPK and collagen by 1, 25-(OH)2-VD3 in rat models of diabetic nephropathy].
Xie X, Li Z, Pi M, Wu J, Zeng W, Zuo L, Zha Y. | 01/14/2017 |
| High Collagen Type III expression is associated with renal fibrosis in experimental kidney diseases. | Serum and urine markers of collagen degradation reflect renal fibrosis in experimental kidney diseases.
Papasotiriou M, Genovese F, Klinkhammer BM, Kunter U, Nielsen SH, Karsdal MA, Floege J, Boor P. | 12/5/2015 |
| Hypoxia alone can upregulate DNA synthesis and expression of collagen type I and III mRNA in adult rat cardiac fibroblasts. | [Hypoxia promote the DNA synthesis and the expression of collagen type I and III mRNA in cultured adult rat cardiac fibroblasts].
Yan J, Gao YQ, Xie ZZ. | 12/22/2012 |
| The mRNA and protein content of collagen I, collagen III and elastin in the abdominal aorta (AA) and femoral artery (FA) was investigated in Wistar-Kyoto rats. | Physiological regulation of extracellular matrix collagen and elastin in the arterial wall of rats by noradrenergic tone and angiotensin II.
Dab H, Kacem K, Hachani R, Dhaouadi N, Hodroj W, Sakly M, Randon J, Bricca G. | 06/30/2012 |
| The regulatory effect of melatonin (MLT)cannot be explained by its effect on procollagen gene expression, since neither MLT nor pinealectomy has an influence on alpha1 (I) and alpha1 (III) procollagen mRNA content in the scar. | Melatonin augments expression of the procollagen α1 (I) and α1 (III) genes in the infarcted heart scar of pinealectomized rats.
Drobnik J, Olczak S, Owczarek K, Hrabec Z, Hrabec E. | 09/3/2011 |
| mRNa expression of Col3a1 increases in kidney and decreases in heart under hyperglycaemic/hyperinsulinaemic conditions. | Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions.
Gaikwad AB, Gupta J, Tikoo K. | 01/1/2011 |
| Pioglitazone blocks the excretion of CTGF and collagen type III of cultured hepatic stellate cells. | [Effects of pioglitazone on the morphology and the expression of connective tissue growth factor of transforming growth factor beta-induced rat hepatic stellate cells in vitro].
Jia JB, Liu Y, Chen WH, Liu M, Lu LG. | 07/12/2010 |
| Data show that the aerosolized STAT1 ASON has anti-fibrosis effect, which may result from the lessened production of typeI and typeIII collagen through reducing TNF-alpha, PDGF-BB and TGF-beta1 and inhibiting the decline of IFN-gamma in BALF. | [Effect of signal transducer and activator of transcription 1 antisense oligodeoxynucleotides on inflammatory mediators, type I and type III collagen mRNA of rat pulmonary fibrosis].
Wang WJ, Zeng M, Liu D, Fan XM, Zhu C, Zhan XQ. | 03/15/2010 |
| Expression of procollagen-I and -III were significantly decreased on rat vocal fold postinjury days 1 and 56. | Extracellular matrix gene expression during wound healing of the injured rat vocal fold.
Ohno T, Hirano S, Rousseau B. | 01/21/2010 |
| Results suggest that the TRB3/MAPK signaling pathway participates in the regulation of collagen types I and III by advanced glycation end products. | Differential regulation of collagen types I and III expression in cardiac fibroblasts by AGEs through TRB3/MAPK signaling pathway.
Tang M, Zhong M, Shang Y, Lin H, Deng J, Jiang H, Lu H, Zhang Y, Zhang W., Free PMC Article | 01/21/2010 |
| We found that TGF-beta3 exhibited the highest potency in stimulating COL1A1 and COL3A1. TGF-beta1 exerted antagonistic effects to TGF-beta2 and beta3. | Expression of transforming growth factor beta isoforms and their roles in tendon healing.
Chan KM, Fu SC, Wong YP, Hui WC, Cheuk YC, Wong MW. | 01/21/2010 |
| These results suggest that high glucose accelerates the synthesis of collagen types I and III, and an ERK1/2 cascade in cardiac fibroblasts play an essential role in the control of collagen deposition by high glucose. | High glucose promotes the production of collagen types I and III by cardiac fibroblasts through a pathway dependent on extracellular-signal-regulated kinase 1/2.
Tang M, Zhang W, Lin H, Jiang H, Dai H, Zhang Y. | 01/21/2010 |
| Quinapril treatment reduced the levels of Col3a1 mRNA in congestive myopathic rats. | Quinapril inhibits progression of heart failure and fibrosis in rats with dilated cardiomyopathy after myocarditis.
Juan W, Nakazawa M, Watanabe K, Ma M, Wahed MI, Hasegawa G, Naito M, Yamamoto T, Fuse K, Kato K, Kodama M, Aizawa Y. | 01/21/2010 |
| In cortical bone a prominent discrete subperiosteal domain becomes wider with exercise and contains more numerous collagen III (CIII)-stained fibers, evidence that short-term voluntary exercise augments both cortical and cancellous microarchitecture. | Evidence for an extensive collagen type III proximal domain in the rat femur. II. Expansion with exercise.
Saino H, Luther F, Carter DH, Natali AJ, Turner DL, Shahtaheri SM, Aaron JE. | 01/21/2010 |
| Diminution of collagen type III cortical domain with trabecular atrophy suggests that it has a proactive or reactive role in determining bone mass and strength by facilitating musculoskeletal exchange in a form that is disengaged by ovariectomy. | Evidence for an extensive collagen type III/VI proximal domain in the rat femur. I. Diminution with ovariectomy.
Luther F, Saino H, Carter DH, Aaron JE. | 01/21/2010 |