| ERbeta Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles. | ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles.
Chakravarthi VP, Dilower I, Ghosh S, Borosha S, Mohamadi R, Dahiya V, Vo K, Lee EB, Ratri A, Kumar V, Marsh CA, Fields PE, Rumi MAK., Free PMC Article | 04/23/2024 |
| miR-143 is implicated in growth plate injury by targeting IHH in precartilaginous stem cells. | miR-143 is implicated in growth plate injury by targeting IHH in precartilaginous stem cells.
Zhang FY, Zhen YF, Guo ZX, Dai J, Zhu LQ, Liang PR, Su GH, Zhang WY, Fang JF, Yuan QW, Yao F, Liu Y, Qiao Y, Zhang Y, Guo WL, Liu Y, Wang XD., Free PMC Article | 11/6/2021 |
| The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury. | The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury.
Deng C, Xu L, Zhang Y, Zhao L, Linghu Y, Yu Y., Free PMC Article | 09/11/2021 |
| the Ihh signaling pathway may activate the occurrence of Temporomandibular joint osteoarthritis by mediating the hypertrophy of chondrocytes | Expression of Ihh signaling pathway in condylar cartilage after bite-raising in adult rats.
Long HQ, Tian PF, Guan YX, Liu LX, Wu XP, Li B. | 02/1/2020 |
| IHH signaling pathway is active during the tendon-bone healing process and appears to be mechanosensitive | Indian hedgehog signaling and the role of graft tension in tendon-to-bone healing: Evaluation in a rat ACL reconstruction model.
Carbone A, Carballo C, Ma R, Wang H, Deng X, Dahia C, Rodeo S., Free PMC Article | 08/20/2016 |
| Increased Ihh is associated with the severity of osteoarthritis cartilage damage. | Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint.
Zhang C, Wei X, Chen C, Cao K, Li Y, Jiao Q, Ding J, Zhou J, Fleming BC, Chen Q, Shang X, Wei L., Free PMC Article | 01/17/2015 |
| The PTHrP and Ihh gene expressions decreased by 75 and 81%, respectively, although their protein expressions increased in surgically induced osteoarthritis. | The expressions of the SOX trio, PTHrP (parathyroid hormone-related peptide)/IHH (Indian hedgehog protein) in surgically induced osteoarthritis of the rat.
Kim SY, Im GI. | 07/30/2011 |
| investigation of role of Ihh in protection of insulin-secreting cells from pro-apoptotic effects of cytokines: cytokines increased Ihh expression; inhibition of hedgehog signaling or Ihh knockdown increased cytokine-induced apoptosis | Protective effect of hedgehog signaling on cytokine-induced cytotoxicity in pancreatic beta-cells.
Umeda H, Ozaki N, Mizutani N, Fukuyama T, Nagasaki H, Arima H, Oiso Y. | 03/26/2011 |
| Ihh signaling pathway plays an important role in regulating the proliferation and apoptosis of precartilaginous stem cells. | Blocking Ihh signaling pathway inhibits the proliferation and promotes the apoptosis of PSCs.
Xu K, Guo F, Zhang S, Liu C, Wang F, Zhou Z, Chen A. | 02/5/2011 |
| These results suggest that Ihh expression is maintained at a high level until the initiation of implantation, while the expression of Gli1 is decreased just prior to the initiation of implantation depending on the estradiol action. | Steroidal regulation of Ihh and Gli1 expression in the rat uterus.
Kubota K, Yamauchi N, Yamagami K, Nishimura S, Gobaru T, Yamanaka K, Wood C, Soh T, Takahashi M, Hattori MA. | 07/26/2010 |
| Bone malformations associated with defective cytochrome P450 oxidoreductase activity are due to reduced cholesterol synthesis and, in turn, reduced Indian hedgehog expression in chondrocytes. | P450 oxidoreductase expressed in rat chondrocytes modulates chondrogenesis via cholesterol- and Indian Hedgehog-dependent mechanisms.
Aguilar A, Wu S, De Luca F. | 01/21/2010 |
| Ihh is a predominant Hh protein in the rat uterus during early pregnancy. | Expression of hedgehog family genes in the rat uterus during early pregnancy.
Kubota K, Yamauchi N, Matsumoto K, Watanabe R, Oozono S, Aramaki S, Wood C, Soh T, Hattori MA. | 01/21/2010 |
| central role of MAPK in the regulation of Ihh in CFK-2 chondrocytic cells | Regulation of Indian hedgehog mRNA levels in chondrocytic cells by ERK1/2 and p38 mitogen-activated protein kinases.
Lai LP, DaSilva KA, Mitchell J. | 01/21/2010 |
| Indian hedgehog harbors the capacity to induce rather than inhibit chondrogenic differentiation; PTHrP antagonizes Hedgehog-mediated differentiation through a protein kinase A-dependent mechanism. | Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA.
Deckelbaum RA, Chan G, Miao D, Goltzman D, Karaplis AC. | 01/21/2010 |
| mechanical loading in a repeated manner triggers the expression of Ihh, which in turn increases the number of replicating mesenchymal cells as well as the amount of the cartilage formed to increase condylar growth | Repeated mechanical loading enhances the expression of Indian hedgehog in condylar cartilage.
Ng TC, Chiu KW, Rabie AB, Hägg U. | 01/21/2010 |
| in silico analysis of rat Desert hedgehog and Indian hedgehog genes | Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
Katoh Y, Katoh M. | 01/21/2010 |