| O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency. | O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency.
Zhao FY, Chen X, Wang JM, Yuan Y, Li C, Sun J, Wang HQ. | 07/24/2024 |
| Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells. | Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells.
Ben Ahmed A, Scache J, Mortuaire M, Lefebvre T, Vercoutter-Edouart AS. | 07/11/2024 |
| O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis. | O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis.
Vang S, Helton ES, Guo Y, Burpee B, Rose E, Easter M, Bollenbecker S, Hirsch MJ, Matthews EL, Jones LI, Howze PH 4th, Rajasekaran V, Denson R, Cochran P, Attah IK, Olson H, Clair G, Melkani G, Krick S, Barnes JW., Free PMC Article | 04/30/2024 |
| Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Lu P, Liu Y, He M, Cao T, Yang M, Qi S, Yu H, Gao H., Free PMC Article | 11/3/2023 |
| Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. | Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Blankenship CM, Xie J, Benz C, Wang A, Ivarsson Y, Jiang J., Free PMC Article | 11/1/2023 |
| Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. | Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263.
Wang L, Li G, Zhou Z, Ge C, Chen Q, Liu Y, Zhang N, Zhang K, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y. | 07/25/2023 |
| LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway. | LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway.
Sun MX, An HY, Sun YB, Sun YB, Bai B., Free PMC Article | 01/28/2023 |
| O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes. | O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes.
Cui Y, Cruz M, Palatnik A, Olivier-Van Stichelen S., Free PMC Article | 01/21/2023 |
| O-GlcNAc transferase regulates p21 protein levels and cell proliferation through the FoxM1-Skp2 axis in a p53-independent manner. | O-GlcNAc transferase regulates p21 protein levels and cell proliferation through the FoxM1-Skp2 axis in a p53-independent manner.
de Queiroz RM, Moon SH, Prives C., Free PMC Article | 10/22/2022 |
| EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association. | EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association.
Wang Y, Shu H, Liu J, Jin X, Wang L, Qu Y, Xia M, Peng P, Feng Y, Wei M., Free PMC Article | 10/15/2022 |
| O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation. | O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation.
Ciraku L, Bacigalupa ZA, Ju J, Moeller RA, Le Minh G, Lee RH, Smith MD, Ferrer CM, Trefely S, Izzo LT, Doan MT, Gocal WA, D'Agostino L, Shi W, Jackson JG, Katsetos CD, Wellen KE, Snyder NW, Reginato MJ., Free PMC Article | 08/6/2022 |
| P53 suppresses the progression of hepatocellular carcinoma via miR-15a by decreasing OGT expression and EZH2 stabilization. | P53 suppresses the progression of hepatocellular carcinoma via miR-15a by decreasing OGT expression and EZH2 stabilization.
You Z, Peng D, Cao Y, Zhu Y, Yin J, Zhang G, Peng X., Free PMC Article | 02/19/2022 |
| Upregulation of OGT by Caveolin-1 promotes hepatocellular carcinoma cell migration and invasion. | Upregulation of OGT by Caveolin-1 promotes hepatocellular carcinoma cell migration and invasion.
Wang L, Feng Y, Zhang C, Chen X, Huang H, Li W, Zhang J, Liu Y. | 02/19/2022 |
| TET3- and OGT-Dependent Expression of Genes Involved in Epithelial-Mesenchymal Transition in Endometrial Cancer. | TET3- and OGT-Dependent Expression of Genes Involved in Epithelial-Mesenchymal Transition in Endometrial Cancer.
Ciesielski P, Jóźwiak P, Forma E, Krześlak A., Free PMC Article | 02/5/2022 |
| Inhibition of O-GlcNAc Transferase Alters the Differentiation and Maturation Process of Human Monocyte Derived Dendritic Cells. | Inhibition of O-GlcNAc Transferase Alters the Differentiation and Maturation Process of Human Monocyte Derived Dendritic Cells.
Weiss M, Anderluh M, Gobec M., Free PMC Article | 01/22/2022 |
| CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of beta-catenin. | CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin.
Hua Q, Zhang B, Xu G, Wang L, Wang H, Lin Z, Yu D, Ren J, Zhang D, Zhao L, Zhang T. | 01/1/2022 |
| Regulation of O-Linked N-Acetyl Glucosamine Transferase (OGT) through E6 Stimulation of the Ubiquitin Ligase Activity of E6AP. | Regulation of O-Linked N-Acetyl Glucosamine Transferase (OGT) through E6 Stimulation of the Ubiquitin Ligase Activity of E6AP.
Peng K, Liu R, Jia C, Wang Y, Jeong GH, Zhou L, Hu R, Kiyokawa H, Yin J, Zhao B., Free PMC Article | 11/6/2021 |
| OGT Protein Interaction Network (OGT-PIN): A Curated Database of Experimentally Identified Interaction Proteins of OGT. | OGT Protein Interaction Network (OGT-PIN): A Curated Database of Experimentally Identified Interaction Proteins of OGT.
Ma J, Hou C, Li Y, Chen S, Wu C., Free PMC Article | 10/30/2021 |
| The crosstalk network of XIST/miR-424-5p/OGT mediates RAF1 glycosylation and participates in the progression of liver cancer. | The crosstalk network of XIST/miR-424-5p/OGT mediates RAF1 glycosylation and participates in the progression of liver cancer.
Ning D, Chen J, Du P, Liu Q, Cheng Q, Li X, Zhang B, Chen X, Jiang L. | 08/7/2021 |
| Feedback Regulation of O-GlcNAc Transferase through Translation Control to Maintain Intracellular O-GlcNAc Homeostasis. | Feedback Regulation of O-GlcNAc Transferase through Translation Control to Maintain Intracellular O-GlcNAc Homeostasis.
Lin CH, Liao CC, Chen MY, Chou TY., Free PMC Article | 07/10/2021 |
| Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells. | Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells.
Raab S, Gadault A, Very N, Decourcelle A, Baldini S, Schulz C, Mortuaire M, Lemaire Q, Hardivillé S, Dehennaut V, El Yazidi-Belkoura I, Vercoutter-Edouart AS, Panasyuk G, Lefebvre T., Free PMC Article | 07/10/2021 |
| Exosomal O-GlcNAc transferase from esophageal carcinoma stem cell promotes cancer immunosuppression through up-regulation of PD-1 in CD8(+) T cells. | Exosomal O-GlcNAc transferase from esophageal carcinoma stem cell promotes cancer immunosuppression through up-regulation of PD-1 in CD8(+) T cells.
Yuan Y, Wang L, Ge D, Tan L, Cao B, Fan H, Xue L. | 06/26/2021 |
| Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase. | Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase.
Levine ZG, Potter SC, Joiner CM, Fei GQ, Nabet B, Sonnett M, Zachara NE, Gray NS, Paulo JA, Walker S., Free PMC Article | 06/12/2021 |
| Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. | Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.
Seo HG, Kim HB, Yoon JY, Kweon TH, Park YS, Kang J, Jung J, Son S, Yi EC, Lee TH, Yang WH, Cho JW., Free PMC Article | 04/24/2021 |
| Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe. | Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe.
Kositzke A, Fan D, Wang A, Li H, Worth M, Jiang J., Free PMC Article | 04/24/2021 |