| Fc receptor-like A promotes malignant behavior in renal cell carcinoma and correlates with tumor immune infiltration. | Fc receptor-like A promotes malignant behavior in renal cell carcinoma and correlates with tumor immune infiltration.
Liu JP, Jiang YF, Liu JW, Tian CJ, Lin YZ, Yang YZ, Zhang ZK, Fang YL, Huang B, Lin H., Free PMC Article | 09/13/2024 |
| Development and Validation of the B Cell-Associated Fc Receptor-like Molecule-Based Prognostic Signature in Skin Cutaneous Melanoma. | Development and Validation of the B Cell-Associated Fc Receptor-like Molecule-Based Prognostic Signature in Skin Cutaneous Melanoma.
Liu Y, Chen Y, Hu X, Meng J, Li X., Free PMC Article | 05/8/2021 |
| FCRLA has long been viewed as a B cell specific protein, and this is the first time its expression has also been shown in human plasmacytoid dendritic cells | B cell-specific protein FCRLA is expressed by plasmacytoid dendritic cells in humans.
Reshetnikova E, Guselnikov S, Volkova O, Baranov K, Taranin A, Mechetina L. | 07/13/2019 |
| FCRLA-A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells | FCRLA-A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells.
Blackburn TE, Santiago T, Burrows PD. | 05/25/2019 |
| This first genome-wide association approach for cyclophosphamide response in lupus nephritis patients yielded a robust profile of genetic associations including large-effect SNP in the FCGR2B-FCRLA locus, which may provide better insights to cyclophosphamide metabolism and efficacy. | Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.
Kim K, Bang SY, Joo YB, Kim T, Lee HS, Kang C, Bae SC. | 12/9/2017 |
| FCGR2C SNPs that associated with vaccine efficacy in RV144 also strongly associated with the expression of FCGR2A/C and one of them also associated with the expression of Fc receptor-like A (FCRLA), another Fc-gamma receptor (FcgammaR) gene | FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.
Peng X, Li SS, Gilbert PB, Geraghty DE, Katze MG., Free PMC Article | 08/13/2016 |
| alternative splicing of FCRLA mRNA results in the production of isoforms differing by their domain composition and possessing either the short or long signal peptide. | Characterization of human FCRLA isoforms.
Kulemzin S, Chikaev N, Volkova O, Reshetnikova E, Taranin A, Najakshin A, Mechetina L. | 03/22/2014 |
| The studies reported here demonstrate that FCRLA is more broadly expressed among human B lineage cells than originally reported; it is found at significant levels in resting blood B cells and at varying levels in all B-cell subsets in tonsil. | FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA.
Santiago T, Kulemzin SV, Reshetnikova ES, Chikaev NA, Volkova OY, Mechetina LV, Zhao M, Davis RS, Taranin AV, Najakshin AM, Hendershot LM, Burrows PD., Free PMC Article | 03/26/2011 |
| Analysis of human cell lines has confirmed that FcRLA is not secreted but is maintained as an intracellular protein in B cells where it interacts with immunoglobulins. | Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses.
Wilson TJ, Gilfillan S, Colonna M. | 10/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. | 04/7/2010 |
| FCRL/FREB may function in melanocytes and melanoma and may be useful for development of diagnostic methods for various pigment disorders and immunotherapy of melanoma. | Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients.
Inozume T, Matsuzaki Y, Kurihara S, Fujita T, Yamamoto A, Aburatani H, Shimada S, Kawakami Y. | 01/21/2010 |
| The concentration of FREB FCRL in patients with rheumatoid arthritis is three times higher than in healthy adults. | Soluble FcgammaRIIIa as a marker for rheumatoid arthritis: the use of genetics in selected populations to study pathogenetic pathways.
Huizinga TW, Ioan-Facsinay A. | 01/21/2010 |