| Bone morphogenetic protein-7 attenuates pancreatic damage under diabetic conditions and prevents progression to diabetic nephropathy via inhibition of ferroptosis. | Bone morphogenetic protein-7 attenuates pancreatic damage under diabetic conditions and prevents progression to diabetic nephropathy via inhibition of ferroptosis.
Song SH, Han D, Park K, Um JE, Kim S, Ku M, Yang J, Yoo TH, Yook JI, Kim NH, Kim HS., Free PMC Article | 06/21/2023 |
| Differentiation of rat bone marrow mesenchymal stem cells into neurons induced by bone morphogenetic protein 7 in vitro. | Differentiation of rat bone marrow mesenchymal stem cells into neurons induced by bone morphogenetic protein 7 in vitro.
Zhang H, Gao L, Zhang W, Li K. | 05/5/2023 |
| BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity. | BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity.
Yu XJ, Wang YG, Lu R, Guo XZ, Qu YK, Wang SX, Xu HR, Kang H, You HB, Xu Y., Free PMC Article | 03/7/2023 |
| Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells. | Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells.
Kim Y, Yu N, Jang YE, Lee E, Jung Y, Lee DJ, Taylor WR, Jo H, Kim J, Lee S, Kang SW., Free PMC Article | 02/25/2023 |
| Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease. | Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease.
Manzano-Lista FJ, Sanz-Gómez M, González-Moreno D, Vega-Martín E, Gil-Ortega M, Schulz A, Rubio MÁ, Ruiz-Hurtado G, Ruilope LM, Aránguez I, Kreutz R, Fernández-Alfonso MS., Free PMC Article | 01/21/2023 |
| Overexpression of bone morphogenetic protein 7 reduces oligodendrocytes loss and promotes functional recovery after spinal cord injury. | Overexpression of bone morphogenetic protein 7 reduces oligodendrocytes loss and promotes functional recovery after spinal cord injury.
Liu S, Zhang W, Yang L, Zhou F, Liu P, Wang Y., Free PMC Article | 02/26/2022 |
| Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-beta1 in renal fibrosis. | Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis.
Liu W, Gu R, Lou Y, He C, Zhang Q, Li D. | 11/13/2021 |
| Bone Morphogenetic Protein-7 (BMP-7) Promotes Neuronal Differentiation of Bone Marrow Mesenchymal Stem Cells (BMSCs) In Vitro. | Bone Morphogenetic Protein-7 (BMP-7) Promotes Neuronal Differentiation of Bone Marrow Mesenchymal Stem Cells (BMSCs) In Vitro.
Zhang H, Zhang W, Bai G, Gao L, Li K., Free PMC Article | 05/22/2021 |
| BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation. | BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
Yang Z, Li X, Jia H, Bai Y, Wang W. | 09/19/2020 |
| Therapeutic effect of liraglutide on expression of CTGF and BMP-7 in induced diabetic nephropathy. | Therapeutic effect of liraglutide on expression of CTGF and BMP-7 in induced diabetic nephropathy.
Ramzy MM, Abdalla AM, Zenhom NM, Okasha AM, Abdelkafy AE, Saleh RK. | 09/19/2020 |
| BMP-7 protects male and female rodents against neuropathic pain induced by nerve injury through a mechanism mediated by endogenous opioids. | BMP-7 protects male and female rodents against neuropathic pain induced by nerve injury through a mechanism mediated by endogenous opioids.
de la Puerta R, Carcelén M, Francés R, de la Fuente R, Hurlé MA, Tramullas M. | 08/29/2020 |
| miR-542-3p regulates osteogenic differentiation of vascular smooth muscle cell through targeting BMP7. | Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7.
Liu H, Wang H, Yang S, Qian D., Free PMC Article | 05/23/2020 |
| BMP-7/Smads-induced Id2 upregulation and Id2/Twist interaction was involved in attenuating diabetic renal tubulointerstitial fibrosis. | BMP-7/Smads-induced inhibitor of differentiation 2 (Id2) upregulation and Id2/Twist interaction was involved in attenuating diabetic renal tubulointerstitial fibrosis.
Xiao Y, Jiang X, Peng C, Zhang Y, Xiao Y, Liang D, Shi M, Wang Y, Zhang F, Guo B. | 03/21/2020 |
| axonal regeneration could be induced via upregulation of endogenous BMP-7 on SCs by PTH (1-34) administration. | BMP-7/Smad expression in dedifferentiated Schwann cells during axonal regeneration and upregulation of endogenous BMP-7 following administration of PTH (1-34).
Kokubu N, Tsujii M, Akeda K, Iino T, Sudo A. | 10/5/2019 |
| The present study demonstrated that BMP7 may serve an important role in alveolar development in a bronchopulmonary dysplasia model. BMP7 may be involved in abnormal alveolar development through the regulation of LF proliferation. | BMP7 regulates lung fibroblast proliferation in newborn rats with bronchopulmonary dysplasia.
Sun Y, Fu J, Xue X, Yang H, Wu L., Free PMC Article | 09/15/2018 |
| Together, these results established that BMP7 is a negative regulator for peripheral myelin gene expression and that p38 MAPK/c-Jun axis might be the main downstream target of BMP7 in this process. | BMP7 retards peripheral myelination by activating p38 MAPK in Schwann cells.
Liu X, Zhao Y, Peng S, Zhang S, Wang M, Chen Y, Zhang S, Yang Y, Sun C., Free PMC Article | 05/5/2018 |
| BMP7 may ameliorate diabetic nephropathy and renal fibrosis via increasing the expression of SnoN mRNA and protein in renal tubular epithelial cells, rather than directly inhibiting the degradation of SnoN by E3 ubiquitin ligase. | BMP-7 enhances SnoN mRNA expression in renal tubular epithelial cells under high-glucose conditions.
Wang Y, Xiao Y, Li S, Shi L, Liu L, Zhang Y, Shi M, Guo B., Free PMC Article | 04/28/2018 |
| The in vivo results revealed higher osteogenesis in the defects filled with the B2BMP-7 excreting BM-MSCs/scaffolds compared to the other two groups. | Acceleration of bone regeneration in bioactive glass/gelatin composite scaffolds seeded with bone marrow-derived mesenchymal stem cells over-expressing bone morphogenetic protein-7.
Kargozar S, Hashemian SJ, Soleimani M, Milan PB, Askari M, Khalaj V, Samadikuchaksaraie A, Hamzehlou S, Katebi AR, Latifi N, Mozafari M, Baino F. | 08/5/2017 |
| The anti-fibrotic effect of bone marrow mesenchymal stem cells (BMSCs) can be strengthened by bone morphogenetic protein-7 (BMP-7) on silica-induced pulmonary fibrosis. | Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis.
Li X, An G, Wang Y, Liang D, Zhu Z, Lian X, Niu P, Guo C, Tian L. | 06/3/2017 |
| Cpd 861 markedly upregulated the gene expression of BMP7 and Smad5, as well as the protein expression of BMP7 and Smad1/5. In addition, p-Smad1/5/8 protein expression was markedly increased by Cpd 861 in the liver fibrosis model. | Attenuation of liver fibrosis by herbal compound 861 via upregulation of BMP-7/Smad signaling in the bile duct ligation model rat.
Hou F, Liu R, Liu X, Cui L, Wen Y, Yan S, Yin C. | 02/25/2017 |
| overexpression of miRNA-21 counteracts the inhibitory effect of BMP-7 on TGF-beta1-induced fibronectin secretion and apoptosis. | BMP-7 Attenuates TGF-β1-Induced Fibronectin Secretion and Apoptosis of NRK-52E Cells by the Suppression of miRNA-21.
Yu Z, Zai-Chun X, Wun-Lun H, Yun-Yun Z., Free PMC Article | 12/31/2016 |
| the role of BMP-7 and its downstream signals in the neuroprotective effects of oxygen-glucose deprivation preconditioning | Oxygen-glucose deprivation preconditioning protects neurons against oxygen-glucose deprivation/reperfusion induced injury via bone morphogenetic protein-7 mediated ERK, p38 and Smad signalling pathways.
Guan J, Du S, Lv T, Qu S, Fu Q, Yuan Y. | 10/22/2016 |
| Adenovirus-mediated FoxC2 expression enhances BMP7-facilitated anabolism in nucleus pulposus cells of the intervertebral discs. | FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc.
Wang Z, Fu C, Chen Y, Xu F, Wang Z, Qu Z, Liu Y., Free PMC Article | 07/16/2016 |
| Authors investigated the expression and secretion of lubricin in BMSCs treated with different combinations of TGF-beta1, BMP-7, and/or KGN. | Kartogenin, transforming growth factor-β1 and bone morphogenetic protein-7 coordinately enhance lubricin accumulation in bone-derived mesenchymal stem cells.
Liu C, Ma X, Li T, Zhang Q. | 05/28/2016 |
| Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 induced the expression of the alphaV sub-unit. | Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis.
Garciadiego-Cázares D, Aguirre-Sánchez HI, Abarca-Buis RF, Kouri JB, Velasquillo C, Ibarra C., Free PMC Article | 04/23/2016 |