| Endosomal actin branching, fission, and receptor recycling require FCHSD2 recruitment by MICAL-L1. | Endosomal actin branching, fission, and receptor recycling require FCHSD2 recruitment by MICAL-L1.
Frisby D, Murakonda AB, Ashraf B, Dhawan K, Almeida-Souza L, Naslavsky N, Caplan S. | 10/29/2024 |
| MICAL-L1 is required for cargo protein delivery to the cell surface. | MICAL-L1 is required for cargo protein delivery to the cell surface.
Sikora R, Bun P, Danglot L, Alqabandi M, Bassereau P, Niedergang F, Galli T, Zahraoui A., Free PMC Article | 01/22/2022 |
| Defining the protein and lipid constituents of tubular recycling endosomes. | Defining the protein and lipid constituents of tubular recycling endosomes.
Farmer T, Xie S, Naslavsky N, Stöckli J, James DE, Caplan S., Free PMC Article | 08/21/2021 |
| A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis. | A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis.
Malinova TS, Angulo-Urarte A, Nüchel J, Tauber M, van der Stoel MM, Janssen V, de Haan A, Groenen AG, Tebbens M, Graupera M, Plomann M, Huveneers S., Free PMC Article | 06/5/2021 |
| Data support the notion that a pool of centriolar gamma-tubulin and/or alpha-tubulin-beta-tubulin heterodimers anchor MICAL-L1 to the centriole, where it might recruit EHD1 to promote ciliogenesis. | MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium.
Xie S, Farmer T, Naslavsky N, Caplan S., Free PMC Article | 07/25/2020 |
| Findings found that ectopic expression of MICALL1 significantly inhibited the proliferation of HCT116 colorectal cancer cells. Also, MICALL1 expression was found to be suppressed in colorectal cancer with p53 mutations. | Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.
Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K. | 04/28/2018 |
| suggesting an EHD1-independent function for MICAL-L1 earlier in mitosis | Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.
Reinecke JB, Katafiasz D, Naslavsky N, Caplan S., Free PMC Article | 01/30/2016 |
| DGKalpha generates phosphatidic acid to drive its own recruitment to tubular recycling endosomes via its interaction with MICAL-L1 | Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling.
Xie S, Naslavsky N, Caplan S., Free PMC Article | 01/24/2015 |
| MICAL-L1-mediated recruitment of EHD1 to Src-containing recycling endosomes is required for the release of Src from the perinuclear endocytic recycling compartment in response to growth factor stimulation. | Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1.
Reinecke JB, Katafiasz D, Naslavsky N, Caplan S., Free PMC Article | 12/6/2014 |
| Cooperation of MICAL-L1, pacsin 2 (syndapin2), and phosphatidic acid in tubular recycling endosome biogenesis. | Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Giridharan SS, Cai B, Vitale N, Naslavsky N, Caplan S., Free PMC Article | 12/21/2013 |
| Rab35 is a critical upstream regulator of MICAL-L1 and Arf6, while both MICAL-L1 and Arf6 regulate Rab8a function. | MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.
Rahajeng J, Giridharan SS, Cai B, Naslavsky N, Caplan S., Free PMC Article | 06/16/2012 |
| novel insights into the MICAL-L1/Rab protein complex that can regulate EGFR trafficking at late endocytic pathways. | MICAL-like1 mediates epidermal growth factor receptor endocytosis.
Abou-Zeid N, Pandjaitan R, Sengmanivong L, David V, Le Pavec G, Salamero J, Zahraoui A., Free PMC Article | 01/14/2012 |
| These data implicate MICAL-L1 as an unusual type of Rab effector that regulates endocytic recycling by recruiting and linking EHD1 and Rab8a on membrane tubules. | MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.
Sharma M, Giridharan SS, Rahajeng J, Naslavsky N, Caplan S., Free PMC Article | 03/15/2010 |