Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis. | Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis. Yuan Y, Xu J, Jiang Q, Yang C, Wang N, Liu X, Piao HL, Lu S, Zhang X, Han L, Liu Z, Cai J, Liu F, Chen S, Liu J., Free PMC Article | 05/21/2024 |
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile. | A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile. Lindelöf L, Rantapää-Dahlqvist S, Lundtoft C, Sandling JK, Leonard D, Sayadi A, Rönnblom L, Enocsson H, Sjöwall C, Jönsen A, Bengtsson AA, Hong MG, Diaz-Gallo LM, Bianchi M, Kozyrev SV, Lindblad-Toh K, DISSECT consortium, ImmunoArray consortium, Nilsson Ekdahl K, Nilsson B, Gunnarsson I, Svenungsson E, Eriksson O. | 04/3/2024 |
Loss of ficolin-3 expression is associated with poor prognosis in patients with hepatocellular carcinoma. | Loss of ficolin-3 expression is associated with poor prognosis in patients with hepatocellular carcinoma. Chen CC, Yu TH, Wu CC, Hung WC, Lee TL, Tang WH, Tsai IT, Chung FM, Lee YJ, Hsu CC., Free PMC Article | 07/27/2023 |
Ficolin-3 and MASP-2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency. | Ficolin-3 and MASP-2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency. Tereshchenko SY, Smolnikova MV, Freidin MB. | 02/28/2023 |
A Novel Gene Signature Based on CDC20 and FCN3 for Prediction of Prognosis and Immune Features in Patients with Hepatocellular Carcinoma. | A Novel Gene Signature Based on CDC20 and FCN3 for Prediction of Prognosis and Immune Features in Patients with Hepatocellular Carcinoma. Lai X, Wu YK, Hong GQ, Li JK, Luo Q, Yuan J, Dai GH, Liu SQ, Feng HG., Free PMC Article | 04/23/2022 |
Ficolin-3 in rheumatic fever and rheumatic heart disease. | Ficolin-3 in rheumatic fever and rheumatic heart disease. Catarino SJ, Andrade FA, Bavia L, Guilherme L, Messias-Reason IJ. | 01/8/2022 |
Ficolin-3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency. | Ficolin-3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency. Lidani KCF, Andrade FA, Beltrame MH, Chakravarti I, Tizzot MR, Cavalcanti EO, Sandri TL, Luz PR, Messias-Reason IJ. | 12/18/2021 |
Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population. | Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population. Li Y, You EQ, Lin WH, Liu XN, Shen DP, Zhang XL, Ma DC, Li HM., Free PMC Article | 11/13/2021 |
FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress. | FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress. Jang H, Jun Y, Kim S, Kim E, Jung Y, Park BJ, Lee J, Kim J, Lee S, Kim J., Free PMC Article | 10/16/2021 |
The clinical value of ficolin-3 gene polymorphism in rheumatic heart disease. An Egyptian adolescents study. | The clinical value of ficolin-3 gene polymorphism in rheumatic heart disease. An Egyptian adolescents study. Gomaa MH, Khidr EG, Elshafei A, Hamza HS, Fattouh AM, El-Husseiny AA, Aglan A, Eldeib MG., Free PMC Article | 07/17/2021 |
Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults. | Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults. Sokołowska A, Świerzko AS, Gajek G, Gołos A, Michalski M, Nowicki M, Szala-Poździej A, Wolska-Washer A, Brzezińska O, Wierzbowska A, Jamroziak K, Kowalski ML, Thiel S, Matsushita M, Jensenius JC, Cedzyński M., Free PMC Article | 01/16/2021 |
Circulating Ficolin-2 and Ficolin-3 Form Heterocomplexes. | Circulating Ficolin-2 and Ficolin-3 Form Heterocomplexes. Jarlhelt I, Pilely K, Clausen JB, Skjoedt MO, Bayarri-Olmos R, Garred P. | 10/24/2020 |
Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus. | Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus. Barkai LJ, Sipter E, Csuka D, Prohászka Z, Pilely K, Garred P, Hosszúfalusi N., Free PMC Article | 09/5/2020 |
the relationship between death risk and serum ficolin-3 levels in patients with esophageal cancer | Evaluation of Ficolin-3 as a Potential Prognostic Serum Biomarker in Chinese Patients with Esophageal Cancer. Li Q, Lin Y. | 01/18/2020 |
increased SFRP4 and ficolin-3 levels are significantly associated with gestational diabetes mellitus development and might be important risk factors for this pregnancy complication. | Increased secreted frizzled-related protein 4 and ficolin-3 levels in gestational diabetes mellitus women. Yuan XS, Zhang M, Wang HY, Jiang J, Yu B. | 10/6/2018 |
Study found the ratio of ficolin-3/adiponectin at 16-18 weeks of gestation was changed in pregnant women who subsequently developed gestational diabetes mellitus GDM, and might provide effective early predicting and screening for GDM. | Ficolin-3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women. Yuan XS, Shi H, Wang HY, Yu B, Jiang J., Free PMC Article | 08/25/2018 |
Ficolin-3 was overexpressed in the serum of most hepatocellular carcinoma patients after Radiofrequency ablation . Ficolin-3 might be a biomarker for Radiofrequency ablation treatment efficacy and a potential target for hepatocellular carcinoma immunotherapy. | Screening for immune-potentiating antigens from hepatocellular carcinoma patients after radiofrequency ablation by serum proteomic analysis. Shen S, Peng H, Wang Y, Xu M, Lin M, Xie X, Peng B, Kuang M., Free PMC Article | 08/18/2018 |
Serum H-ficolin levels inversely correlated with ground-glass opacity score on chest computed tomography in systemic sclerosis-interstitial lung disease (SSc-ILD) patients. H-ficolin-related innate immunity may be involved in SSc-ILD development. | Serum H-ficolin levels: Clinical association with interstitial lung disease in patients with systemic sclerosis. Miyagawa T, Asano Y, de Mestier Y, Saigusa R, Taniguchi T, Yamashita T, Nakamura K, Hirabayashi M, Miura S, Ichimura Y, Takahashi T, Yoshizaki A, Miyagaki T, Sugaya M, Sato S. | 06/2/2018 |
Ficolin-3 plasma levels are associated with the presence and progression of abdominal aortic aneurysm (AAA), suggesting its potential role as a biomarker of AAA | Association of ficolin-3 with abdominal aortic aneurysm presence and progression. Fernandez-García CE, Burillo E, Lindholt JS, Martinez-Lopez D, Pilely K, Mazzeo C, Michel JB, Egido J, Garred P, Blanco-Colio LM, Martin-Ventura JL. | 02/3/2018 |
results suggest that anti-ficolin-3 antibodies could be useful for the diagnosis of active nephritis in SLE patients | Association between the Presence of Autoantibodies Targeting Ficolin-3 and Active Nephritis in Patients with Systemic Lupus Erythematosus. Plawecki M, Lheritier E, Clavarino G, Jourde-Chiche N, Ouili S, Paul S, Gout E, Sarrot-Reynauld F, Bardin N, Boëlle PY, Chiche L, Bouillet L, Thielens NM, Cesbron JY, Dumestre-Pérard C., Free PMC Article | 08/5/2017 |
this study shows that H-ficolin may aid clearance of influenza A virus by promoting monocyte uptake of the virus, while reducing viral replication and virus-induced TNF-a responses in these cells | Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production. White MR, Tripathi S, Verma A, Kingma P, Takahashi K, Jensenius J, Thiel S, Wang G, Crouch EC, Hartshorn KL. | 07/1/2017 |
These results suggest that polymorphisms in the FCN3 gene cooperate to increase ficolin-3 concentration and that it might contribute to leprosy susceptibility by favoring Mycobacterium leprae infection. | Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy. Andrade FA, Beltrame MH, Bini VB, Gonçalves LB, Boldt AB, de Messias-Reason IJ., Free PMC Article | 06/24/2017 |
subjects that were heterozygote carriers of both FCN2 + 6424 and FCN3 + 1637delC were sufficient mannan-binding lectin producers | Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes. Bjarnadottir H, Arnardottir M, Ludviksson BR., Free PMC Article | 05/13/2017 |
in patients with systemic lupus erythematosus, there was no significant association between ficolin-1 and ficolin-3 with lupus nephritis | Plasma ficolin levels and risk of nephritis in Danish patients with systemic lupus erythematosus. Tanha N, Pilely K, Faurschou M, Garred P, Jacobsen S. | 04/15/2017 |
Monitoring serum H-ficolin levels was shown to be of no benefit in terms of predicting severe infection. | Early Changes of Mannose-Binding Lectin, H-Ficolin, and Procalcitonin in Patients with Febrile Neutropenia: A Prospective Observational Study. Işlak Mutcalı S, Saltoğlu N, Balkan İİ, Özaras R, Yemişen M, Tabak F, Mert A, Öztürk R, Öngören Ş, Başlar Z, Aydın Y, Ferhanoğlu B, Soysal T., Free PMC Article | 03/18/2017 |