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    RUNX1T1 RUNX1 partner transcriptional co-repressor 1 [ Homo sapiens (human) ]

    Gene ID: 862, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CNS erythroblastic sarcoma: a potential emerging pediatric tumor type characterized by NFIA::RUNX1T1/3 fusions.

    CNS erythroblastic sarcoma: a potential emerging pediatric tumor type characterized by NFIA::RUNX1T1/3 fusions.
    Tauziède-Espariat A, Lew-Derivry L, Abbou S, Métais A, Pierron G, Reynaud S, Masliah-Planchon J, Mariet C, Hasty L, Dangouloff-Ros V, Boddaert N, Csanyi M, Aline-Fardin A, Lamaison C, Chrétien F, Beccaria K, Puget S, Varlet P., Free PMC Article

    02/1/2024
    Single-cell RNA-seq reveals novel immune-associated biomarkers for predicting prognosis in AML patients with RUNX1::RUNX1T1.

    Single-cell RNA-seq reveals novel immune-associated biomarkers for predicting prognosis in AML patients with RUNX1::RUNX1T1.
    Li XP, Dai Y, Zhang WN, Pan MM, Mao J, Zhao B, Jiang L, Gao Y.

    11/28/2023
    RUNX1/ETO regulates reactive oxygen species (ROS) levels in t(8,21) acute myeloid leukaemia via FLT3 and RAC1.

    RUNX1/ETO regulates reactive oxygen species (ROS) levels in t(8,21) acute myeloid leukaemia via FLT3 and RAC1.
    Azlan A, Khor KZ, Rajasegaran Y, Rosli AA, Said MSM, Yusoff NM, Moses EJ.

    06/26/2023
    MiR-210-3p accelerates tumor-relevant cell functions of endometrial carcinoma by repressing RUNX1T1.

    MiR-210-3p accelerates tumor-relevant cell functions of endometrial carcinoma by repressing RUNX1T1.
    Dai Z, Luo H, Chen J, Li L.

    12/10/2022
    RUNX1T1 function in cell fate.

    RUNX1T1 function in cell fate.
    Hu N, Zou L, Wang C, Song G., Free PMC Article

    08/6/2022
    Immunohistochemical Staining to Identify Concomitant Systemic Mastocytosis in Acute Myeloid Leukemia with RUNX1::RUNX1T1.

    Immunohistochemical Staining to Identify Concomitant Systemic Mastocytosis in Acute Myeloid Leukemia with RUNX1::RUNX1T1.
    Hwang SM, Kim BJ, Lee JS, Seong MW, Seo SH, Paik JH, Kim SA, Lee JY, Lee JO, Chang YH, Bang SM., Free PMC Article

    07/9/2022
    Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.

    Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.
    Kumar P, Verma V, Mohania D, Gupta S, Babbar AK, Rathi B, Dhanda RS, Yadav M.

    03/19/2022
    RUNX1T1, a potential prognostic marker in breast cancer, is co-ordinately expressed with ERalpha, and regulated by estrogen receptor signalling in breast cancer cells.

    RUNX1T1, a potential prognostic marker in breast cancer, is co-ordinately expressed with ERα, and regulated by estrogen receptor signalling in breast cancer cells.
    Saikia S, Pal U, Kalita DJ, Rai AK, Sarma A, Kataki AC, Limaye AM.

    01/8/2022
    AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms.

    AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms.
    Rejeski K, Duque-Afonso J, Lübbert M., Free PMC Article

    01/1/2022
    Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts.

    Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts.
    Sasaki K, Tsujimoto S, Miyake M, Uchiyama Y, Ikeda J, Yoshitomi M, Shimosato Y, Tokumasu M, Matsuo H, Yoshida K, Ohki K, Kaburagi T, Yamato G, Hara Y, Takeuchi M, Kinoshita A, Tomizawa D, Taga T, Adachi S, Tawa A, Horibe K, Hayashi Y, Matsumoto N, Ito S, Shiba N.

    12/25/2021
    Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.

    Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
    Trinh BQ, Ummarino S, Zhang Y, Ebralidze AK, Bassal MA, Nguyen TM, Heller G, Coffey R, Tenen DE, van der Kouwe E, Fabiani E, Gurnari C, Wu CS, Angarica VE, Yang H, Chen S, Zhang H, Thurm AR, Marchi F, Levantini E, Staber PB, Zhang P, Voso MT, Pandolfi PP, Kobayashi SS, Chai L, Di Ruscio A, Tenen DG., Free PMC Article

    12/11/2021
    Identification of RUNX1T1 as a potential epigenetic modifier in small-cell lung cancer.

    Identification of RUNX1T1 as a potential epigenetic modifier in small-cell lung cancer.
    He T, Wildey G, McColl K, Savadelis A, Spainhower K, McColl C, Kresak A, Tan AC, Yang M, Abbas A, Dowlati A., Free PMC Article

    11/22/2021
    Optimized clinical application of minimal residual disease in acute myeloid leukemia with RUNX1-RUNX1T1.

    Optimized clinical application of minimal residual disease in acute myeloid leukemia with RUNX1-RUNX1T1.
    Wei H, Liu X, Wang Y, Lin D, Zhou C, Liu B, Qiu S, Gu R, Li Y, Wei S, Gong B, Liu K, Gong X, Liu Y, Zhang G, Fang Q, Zhang J, Jin J, Ma Y, Mi Y, Wang J.

    10/9/2021
    Relationships between AML1-ETO and MLL-AF9 fusion gene expressions and hematological parameters in acute myeloid leukemia.

    Relationships between AML1-ETO and MLL-AF9 fusion gene expressions and hematological parameters in acute myeloid leukemia.
    Muddathir ARM, Hamid TAM, Mohamed Elamin E, Khabour OF.

    08/21/2021
    Long non-coding RNA EPB41L4A-AS2 suppresses progression of ovarian cancer by sequestering microRNA-103a to upregulate transcription factor RUNX1T1.

    Long non-coding RNA EPB41L4A-AS2 suppresses progression of ovarian cancer by sequestering microRNA-103a to upregulate transcription factor RUNX1T1.
    Sun T, Yang P, Gao Y.

    05/29/2021
    The RUNX1/RUNX1T1 network: translating insights into therapeutic options.

    The RUNX1/RUNX1T1 network: translating insights into therapeutic options.
    Swart LE, Heidenreich O., Free PMC Article

    04/24/2021
    LncRNA RUNX1-IT1 which is downregulated by hypoxia-driven histone deacetylase 3 represses proliferation and cancer stem-like properties in hepatocellular carcinoma cells.

    LncRNA RUNX1-IT1 which is downregulated by hypoxia-driven histone deacetylase 3 represses proliferation and cancer stem-like properties in hepatocellular carcinoma cells.
    Sun L, Wang L, Chen T, Shi Y, Yao B, Liu Z, Wang Y, Li Q, Liu R, Niu Y, Tu K, Liu Q., Free PMC Article

    03/13/2021
    Definition of a small core transcriptional circuit regulated by AML1-ETO.

    Definition of a small core transcriptional circuit regulated by AML1-ETO.
    Stengel KR, Ellis JD, Spielman CL, Bomber ML, Hiebert SW., Free PMC Article

    02/27/2021
    RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia.

    RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia.
    Grinev VV, Barneh F, Ilyushonak IM, Nakjang S, Smink J, van Oort A, Clough R, Seyani M, McNeill H, Reza M, Martinez-Soria N, Assi SA, Ramanouskaya TV, Bonifer C, Heidenreich O., Free PMC Article

    02/13/2021
    RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.

    RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.
    Chin PS, Assi SA, Ptasinska A, Imperato MR, Cockerill PN, Bonifer C.

    01/16/2021
    Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1-ETO-dependent transcription in t(8;21) AML.

    Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1-ETO-dependent transcription in t(8;21) AML.
    Guo C, Li J, Steinauer N, Wong M, Wu B, Dickson A, Kalkum M, Zhang J., Free PMC Article

    12/12/2020
    [Clinical Prognostic Factors Analysis of Initially Treated AML Children with t(8;21)/RUNX1-RUNX1T1()].

    [Clinical Prognostic Factors Analysis of Initially Treated AML Children with t(8;21)/RUNX1-RUNX1T1()].
    Fan GL, Jiang PJ, Yuan M.

    10/24/2020
    Morphological characteristics, cytogenetic profile, and outcome of RUNX1-RUNX1T1-positive acute myeloid leukemia: Experience of an Indian tertiary care center.

    Morphological characteristics, cytogenetic profile, and outcome of RUNX1-RUNX1T1-positive acute myeloid leukemia: Experience of an Indian tertiary care center.
    Gupta R, Yadav S, Parashar Y, Rahman K, Singh MK, Chandra D, Gupta A, Nityanand S.

    10/3/2020
    Targeting miR-193a-AML1-ETO-beta-catenin axis by melatonin suppresses the self-renewal of leukaemia stem cells in leukaemia with t (8;21) translocation.

    Targeting miR-193a-AML1-ETO-β-catenin axis by melatonin suppresses the self-renewal of leukaemia stem cells in leukaemia with t (8;21) translocation.
    Zhou B, Ye H, Xing C, Liang B, Li H, Chen L, Huang X, Wu Y, Gao S., Free PMC Article

    08/15/2020
    Negative CD19 expression is associated with inferior relapse-free survival in children with RUNX1-RUNX1T1-positive acute myeloid leukaemia: results from the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study.

    Negative CD19 expression is associated with inferior relapse-free survival in children with RUNX1-RUNX1T1-positive acute myeloid leukaemia: results from the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study.
    Sakamoto K, Shiba N, Deguchi T, Kiyokawa N, Hashii Y, Moriya-Saito A, Tomizawa D, Taga T, Adachi S, Horibe K, Imamura T.

    06/20/2020
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