| EIF3B stabilizes PTGS2 expression by counteracting MDM2-mediated ubiquitination to promote the development and progression of malignant melanoma. | EIF3B stabilizes PTGS2 expression by counteracting MDM2-mediated ubiquitination to promote the development and progression of malignant melanoma.
Fang P, Han Y, Qu Y, Wang X, Zhang Y, Zhang W, Zhang N, Li G, Ma W., Free PMC Article | 12/24/2022 |
| Eukaryotic translation initiation factor 3 subunit B could serve as a potential prognostic predictor for breast cancer. | Eukaryotic translation initiation factor 3 subunit B could serve as a potential prognostic predictor for breast cancer.
Song S, Liu J, Zhang M, Gao X, Sun W, Liu P, Wang Y, Li J., Free PMC Article | 02/26/2022 |
| EIF3B Associates with Exacerbated Clinical Features, Poor Treatment Response and Survival in Adult Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Patients. | EIF3B Associates with Exacerbated Clinical Features, Poor Treatment Response and Survival in Adult Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Patients.
Zhu F, Fu Y, He X., Free PMC Article | 02/12/2022 |
| Eukaryotic translation initiation factor 3 subunit b is a novel oncogenic factor in prostate cancer. | Eukaryotic translation initiation factor 3 subunit b is a novel oncogenic factor in prostate cancer.
Xiang P, Sun Y, Fang Z, Yan K, Fan Y. | 07/31/2021 |
| Downregulation of eukaryotic translation initiation factor 3b inhibited proliferation and metastasis of gastric cancer. | Downregulation of eukaryotic translation initiation factor 3b inhibited proliferation and metastasis of gastric cancer.
Ma F, Li X, Ren J, Guo R, Li Y, Liu J, Sun Y, Liu Z, Jia J, Li W., Free PMC Article | 09/12/2020 |
| High EIF3B expression is associated with cervical cancer. | Eukaryotic translation initiation factor 3B is overexpressed and correlates with deteriorated tumor features and unfavorable survival profiles in cervical cancer patients.
Zhu P, Tan Q, Jiang W, Ou Y, Xu P, Yuan L. | 03/21/2020 |
| Inhibition of EIF3B gene expression significantly inhibit the proliferation of ovarian cancer cells and increase the apoptosis of ovarian cancer cells. | Effects of EIF3B gene downregulation on apoptosis and proliferation of human ovarian cancer SKOV3 and HO-8910 cells.
Wang L, Ouyang L. | 04/6/2019 |
| EIF3B overexpression correlates with advanced disease conditions and poor prognosis, and it promotes cells proliferation while inhibits cells apoptosis in NSCLC. | EIF3B correlates with advanced disease stages and poor prognosis, and it promotes proliferation and inhibits apoptosis in non-small cell lung cancer.
Tian Y, Zhao K, Yuan L, Li J, Feng S, Feng Y, Fang Z, Li H, Deng R. | 02/16/2019 |
| Study demonstrated that EIF3B expression was up-regulated in esophageal squamous cell carcinoma cells and negatively correlated with the prognosis of patients. | Eukaryotic translation initiation factor 3B accelerates the progression of esophageal squamous cell carcinoma by activating β-catenin signaling pathway.
Xu F, Xu CZ, Gu J, Liu X, Liu R, Huang E, Yuan Y, Zhao G, Jiang J, Xu C, Chu Y, Lu C, Ge D., Free PMC Article | 12/30/2017 |
| The human eIF3b and octameric eIF3a subunits serve as the nucleation core around which other subunits assemble in an ordered way into two interconnected modules: the yeast-like core and the octamer. | Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer.
Wagner S, Herrmannová A, Šikrová D, Valášek LS., Free PMC Article | 06/24/2017 |
| eIF3 has a role in controlling cell size independently of S6K1-activity | eIF3 controls cell size independently of S6K1-activity.
Schipany K, Rosner M, Ionce L, Hengstschläger M, Kovacic B., Free PMC Article | 08/13/2016 |
| Novel RNA-binding protein P311 binds eIF3b to promote translation of TGF-beta1, TGF-beta2, TGF-beta3. | Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3).
Yue MM, Lv K, Meredith SC, Martindale JL, Gorospe M, Schuger L., Free PMC Article | 03/7/2015 |
| Report EIF3B binding within the IRES domain V of the coxsackie virus B3 mutant strain. | Impaired binding of standard initiation factors eIF3b, eIF4G and eIF4B to domain V of the live-attenuated coxsackievirus B3 Sabin3-like IRES--alternatives for 5'UTR-related cardiovirulence mechanisms.
Souii A, Gharbi J, Ben M'hadheb-Gharbi M., Free PMC Article | 07/12/2014 |
| eIF3b expression relates to human bladder and prostate cancer prognosis, is required for tumor growth, and thus a candidate therapeutic target. | Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization.
Wang H, Ru Y, Sanchez-Carbayo M, Wang X, Kieft JS, Theodorescu D., Free PMC Article | 01/11/2014 |
| EIF3B promotes the proliferation of U87 human glioblastoma cells and may play an important role in human glioblastoma development. | Knockdown of eukaryotic translation initiation factors 3B (EIF3B) inhibits proliferation and promotes apoptosis in glioblastoma cells.
Liang H, Ding X, Zhou C, Zhang Y, Xu M, Zhang C, Xu L. | 04/20/2013 |
| Yeast eIF3b exhibits RNA binding activity but huamn eIF3b doesn't. | Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b.
Khoshnevis S, Neumann P, Ficner R., Free PMC Article | 02/26/2011 |
| a conserved tryptophan residue in the human eIF3j N-terminal acidic motif (NTA) is held in the helix alpha1 and loop 5 hydrophobic pocket of the human eIF3b RNA recognition motif (RRM) | The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selection.
Elantak L, Wagner S, Herrmannová A, Karásková M, Rutkai E, Lukavsky PJ, Valásek L., Free PMC Article | 04/12/2010 |
| structural analysis of the eIF3b RNA recognition motif and its interaction with eIF3j | Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit.
ElAntak L, Tzakos AG, Locker N, Lukavsky PJ. | 01/21/2010 |