| Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation. | Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation.
Alard A, Katsara O, Rios-Fuller T, Parra C, Ozerdem U, Ernlund A, Schneider RJ., Free PMC Article | 10/13/2023 |
| eIF3d controls the persistent integrated stress response. | eIF3d controls the persistent integrated stress response.
Mukhopadhyay S, Amodeo ME, Lee ASY., | 10/2/2023 |
| Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity. | Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity.
She R, Luo J, Weissman JS., Free PMC Article | 07/24/2023 |
| eIF3d: A driver of noncanonical cap-dependent translation of specific mRNAs and a trigger of biological/pathological processes. | eIF3d: A driver of noncanonical cap-dependent translation of specific mRNAs and a trigger of biological/pathological processes.
Ma S, Liu JY, Zhang JT., Free PMC Article | 06/12/2023 |
| EIF3D promoted cervical carcinoma through Warburg effect by interacting with GRP78. | EIF3D promoted cervical carcinoma through Warburg effect by interacting with GRP78.
Liu Q, Liu J, Zheng D, Zhang R, Xiang Y, Xu F, Zhou X, Qin J. | 02/11/2023 |
| Overexpression of Eukaryotic translation initiation factor 3D induces stem cell-like properties and metastasis in cervix cancer by activating FAK through inhibiting degradation of GRP78. | Overexpression of Eukaryotic translation initiation factor 3D induces stem cell-like properties and metastasis in cervix cancer by activating FAK through inhibiting degradation of GRP78.
Zhong Y, Lan J., Free PMC Article | 03/19/2022 |
| EIF3D promotes the progression of preeclampsia by inhibiting of MAPK/ERK1/2 pathway. | EIF3D promotes the progression of preeclampsia by inhibiting of MAPK/ERK1/2 pathway.
Li X, Wang Z, Liu G, Guo J. | 03/5/2022 |
| A DAP5/eIF3d alternate mRNA translation mechanism promotes differentiation and immune suppression by human regulatory T cells. | A DAP5/eIF3d alternate mRNA translation mechanism promotes differentiation and immune suppression by human regulatory T cells.
Volta V, Pérez-Baos S, de la Parra C, Katsara O, Ernlund A, Dornbaum S, Schneider RJ., Free PMC Article | 01/8/2022 |
| Systematic Investigation of mRNA N (6)-Methyladenosine Machinery in Primary Prostate Cancer. | Systematic Investigation of mRNA N (6)-Methyladenosine Machinery in Primary Prostate Cancer.
Jiang M, Lu Y, Duan D, Wang H, Man G, Kang C, Abulimiti K, Li Y., Free PMC Article | 08/28/2021 |
| The current data highlight the importance of eIF3d in HIV infection by inhibiting CD8+ T cell function and promoting viral replication. | Reduced eIF3d accelerates HIV disease progression by attenuating CD8+ T cell function.
Pan Y, Zhang ZN, Yin LB, Fu YJ, Jiang YJ, Shang H., Free PMC Article | 06/20/2020 |
| EIF3D is a novel substrate of CUL3/KCTD10 ubiquitin ligase. The ubiquitin code of EIF3D is K27-polyubiquitination at the lysine 153 and 275 residues. | Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.
Maekawa M, Hiyoshi H, Nakayama J, Kido K, Sawasaki T, Semba K, Kubota E, Joh T, Higashiyama S. | 06/6/2020 |
| Results demonstrated that the overexpression of eIF3D could independently predict poor prognosis for patients with lung adenocarcinoma (LUAD). In silico analysis demonstrated that the altered expression of eIF3D was at least regulated by both copy number alterations (CNAs) and the hypomethylation of cg14297023 site. | Overexpression of eIF3D in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival.
Wang D, Jia Y, Zheng W, Li C, Cui W., Free PMC Article | 05/9/2020 |
| Mechanistical study demonstrated that EIF3D interacted with GRP78 and enhanced protein stability through blocking the ubiquitin-mediated-proteasome degradation of GRP78. | EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation.
Huang H, Gao Y, Liu A, Yang X, Huang F, Xu L, Danfeng X, Chen L., Free PMC Article | 04/4/2020 |
| results indicate that eIF3D plays a key role in the proliferation of AML cells, and suggest that eIF3D silencing might be a potential therapeutic strategy for leukemia. | Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.
Liu GZ, Liu JZ, Li XQ, Zhang L, Li SJ, Xiao TW, Wang JX, Li GY, Liu Y. | 07/14/2018 |
| eIF3d promotes gallbladder cancer (GBC) progression mainly via eIF3d-GRK2-AKT axis and it may be used as a prognostic factor. The therapeutic targeting of eIF3d-GRK2 axis may be a potential treatment approach for GBC. | EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway.
Zhang F, Xiang S, Cao Y, Li M, Ma Q, Liang H, Li H, Ye Y, Zhang Y, Jiang L, Hu Y, Zhou J, Wang X, Zhang Y, Nie L, Liang X, Gong W, Liu Y., Free PMC Article | 03/10/2018 |
| A transcript-specific eIF3 complex mediates global translational control of energy metabolism. | A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism.
Shah M, Su D, Scheliga JS, Pluskal T, Boronat S, Motamedchaboki K, Campos AR, Qi F, Hidalgo E, Yanagida M, Wolf DA., Free PMC Article | 11/18/2017 |
| Results provide evidences that EIF3D may function as a potential proto-oncogene that participates in the occurrence and progression of renal cell carcinoma. | EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling.
Pan XW, Chen L, Hong Y, Xu DF, Liu X, Li L, Huang Y, Cui LM, Gan SS, Yang QW, Huang H, Qu FJ, Ye JQ, Wang LH, Cui XG. | 03/11/2017 |
| Knockdown of eIF3D inhibited breast cancer cell proliferation and invasion. | Knockdown of eIF3D inhibits breast cancer cell proliferation and invasion through suppressing the Wnt/β-catenin signaling pathway.
Fan Y, Guo Y., Free PMC Article | 10/1/2016 |
| eIF3d makes specific contacts with the RNA cap, as exemplified by cap analogue competition, and these interactions are essential for assembly of translation initiation complexes on eIF3-specialized mRNAs such as the cell proliferation regulator c-Jun | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Lee AS, Kranzusch PJ, Doudna JA, Cate JH., Free PMC Article | 09/3/2016 |
| the critical involvement of EIF3D in the survival and progression of melanoma cells | Knockdown of EIF3D suppresses proliferation of human melanoma cells through G2/M phase arrest.
Li H, Zhou F, Wang H, Lin D, Chen G, Zuo X, Sun L, Zhang X, Yang S. | 07/30/2016 |
| EIF3D plays an important role in modulating glioma cell growth and migration. | RNAi-Mediated Silencing of EIF3D Alleviates Proliferation and Migration of Glioma U251 and U87MG Cells.
Ren M, Zhou C, Liang H, Wang X, Xu L. | 07/16/2016 |
| Findings suggest that eukaryotic translation initiation factor 3 subunit D (eIF3D) might play an important role in colon cancer progression. | Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells.
Yu X, Zheng B, Chai R., Free PMC Article | 08/29/2015 |
| eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome. | Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome.
Villa N, Do A, Hershey JW, Fraser CS., Free PMC Article | 01/25/2014 |
| Observational study of gene-disease association. (HuGE Navigator) | RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function.
Liu YL, Fann CS, Liu CM, Chen WJ, Wu JY, Hung SI, Chen CH, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Chang CC, Yang WC, Lin JJ, Chou FH, Faraone SV, Tsuang MT, Hwu HG. | 07/2/2008 |