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    BECN1 beclin 1 [ Homo sapiens (human) ]

    Gene ID: 8678, updated on 9-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Upregulation of miR-499a Targets Beclin1 to Modulate Astrocyte Autophagy and Promote Ischemic Stroke.

    Upregulation of miR-499a Targets Beclin1 to Modulate Astrocyte Autophagy and Promote Ischemic Stroke.
    Xian G, Song D, Wei Y, Huang F, Luo H.

    04/4/2024
    Targeting IL-6/STAT3 signaling abrogates EGFR-TKI resistance through inhibiting Beclin-1 dependent autophagy in HNSCC.

    Targeting IL-6/STAT3 signaling abrogates EGFR-TKI resistance through inhibiting Beclin-1 dependent autophagy in HNSCC.
    Wang Y, Zhou Q, Liu C, Zhang R, Xing B, Du J, Dong L, Zheng J, Chen Z, Sun M, Yao X, Ren Y, Zhou X.

    03/19/2024
    VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation.

    VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation.
    Wang Z, Yan M, Ye L, Zhou Q, Duan Y, Jiang H, Wang L, Ouyang Y, Zhang H, Shen Y, Ji G, Chen X, Tian Q, Xiao L, Wu Q, Meng Y, Liu G, Ma L, Lei B, Lu Z, Xu D., Free PMC Article

    03/19/2024
    THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway.

    THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway.
    Xu Z, Lu J, Gao S, Rui YN., Free PMC Article

    03/13/2024
    Clinical roles of autophagy-related proteins Beclin-1 and mTOR in smoking and non-smoking patients with oral leukoplakia.

    Clinical roles of autophagy-related proteins Beclin-1 and mTOR in smoking and non-smoking patients with oral leukoplakia.
    Zhang P, Zhou P, Yao M., Free PMC Article

    02/15/2024
    GRB2 is a BECN1 interacting protein that regulates autophagy.

    GRB2 is a BECN1 interacting protein that regulates autophagy.
    Montero-Vergara J, Plachetta K, Kinch L, Bernhardt S, Kashyap K, Levine B, Thukral L, Vetter M, Thomssen C, Wiemann S, Peña-Llopis S, Jendrossek V, Vega-Rubin-de-Celis S., Free PMC Article

    01/26/2024
    [Pro-oxidation status of rotator cuff tissue and expression of Beclin-1 and mTOR in patients with rotator cuff injury].

    [Pro-oxidation status of rotator cuff tissue and expression of Beclin-1 and mTOR in patients with rotator cuff injury].
    Liu ZJ, Wei HW, Zheng WP, Wan L, Liao ZH, Chen S.

    01/3/2024
    LncRNA MIAT Modulates LPS-Induced Acute Kidney Injury via BECN1-Dependent Autophagy by Interacting with PTBP1.

    LncRNA MIAT Modulates LPS-Induced Acute Kidney Injury via BECN1-Dependent Autophagy by Interacting with PTBP1.
    Xu M, Zhou Y.

    12/18/2023
    hsa_circRNA_BECN1 acts as a ceRNA to promote polycystic ovary syndrome progression by sponging the miR-619-5p/Rab5b axis.

    hsa_circRNA_BECN1 acts as a ceRNA to promote polycystic ovary syndrome progression by sponging the miR-619-5p/Rab5b axis.
    Fan H, Zhou D, Zhang X, Jiang M, Kong X, Xue T, Gao L, Lu D, Tao C, Wang L.

    11/13/2023
    Structural insights for selective disruption of Beclin 1 binding to Bcl-2.

    Structural insights for selective disruption of Beclin 1 binding to Bcl-2.
    Pan YZ, Liang Q, Tomchick DR, De Brabander JK, Rizo J., Free PMC Article

    11/1/2023
    COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.

    COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.
    Zhang H, Chen S, Xu S, Li X., Free PMC Article

    10/5/2023
    Investigation of Beclin 1 and TNF-alpha expressions in preeclampsia placentas: Immunohistochemical study.

    Investigation of Beclin 1 and TNF-α expressions in preeclampsia placentas: Immunohistochemical study.
    Öcal E, Toprak V, Akalin SA, Aşir F, Deveci E., Free PMC Article

    08/25/2023
    SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.

    SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
    Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F.

    06/25/2023
    SPINK1 contributes to proliferation and clonal formation of HT29 cells through Beclin1 associated enhanced autophagy.

    SPINK1 contributes to proliferation and clonal formation of HT29 cells through Beclin1 associated enhanced autophagy.
    Hu NA, Zhang S, Jin A, Guo L, Qu Z, Wang J., Free PMC Article

    06/22/2023
    Downregulation of Claudin5 promotes malignant progression and radioresistance through Beclin1-mediated autophagy in esophageal squamous cell carcinoma.

    Downregulation of Claudin5 promotes malignant progression and radioresistance through Beclin1-mediated autophagy in esophageal squamous cell carcinoma.
    Huang S, Zhang J, Li Y, Xu Y, Jia H, An L, Wang X, Yang Y., Free PMC Article

    06/21/2023
    Genetically prolonged beige fat in male mice confers long-lasting metabolic health.

    Genetically prolonged beige fat in male mice confers long-lasting metabolic health.
    Wu R, Park J, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y., Free PMC Article

    06/2/2023
    Upregulation of necroptosis markers RIPK3/MLKL and their crosstalk with autophagy-related protein Beclin-1 in primary immune thrombocytopenia.

    Upregulation of necroptosis markers RIPK3/MLKL and their crosstalk with autophagy-related protein Beclin-1 in primary immune thrombocytopenia.
    Kamal AM, Nabih NA, Rakha NM, Sanad EF., Free PMC Article

    05/30/2023
    Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy.

    Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy.
    Popli P, Tang S, Chadchan SB, Talwar C, Rucker EB 3rd, Guan X, Monsivais D, Lydon JP, Stallings CL, Moley KH, Kommagani R., Free PMC Article

    05/28/2023
    RNF113A targeted by miR-197 promotes proliferation and inhibits autophagy via CXCR4/CXCL12/AKT/ERK/Beclin1 axis in cervical cancer.

    RNF113A targeted by miR-197 promotes proliferation and inhibits autophagy via CXCR4/CXCL12/AKT/ERK/Beclin1 axis in cervical cancer.
    Zhang Q, Song J, Cao L, Sun M, Xu T, Yang S, Li S, Wang H, Fu X.

    05/23/2023
    Investigating the mechanism of interactive regulation of B-cell lymphoma-2/Beclin 1 through electroacupuncture intervention during reperfusion in myocardial ischemia-reperfusion injury in a rat model.

    Investigating the mechanism of interactive regulation of B-cell lymphoma-2/Beclin 1 through electroacupuncture intervention during reperfusion in myocardial ischemia-reperfusion injury in a rat model.
    Zhong Z, He P, Hua H, Bai H, Zhang H, Lu S, Qiu W, Gu Y, Qin X.

    05/5/2023
    Aberrant serum and tissue levels of Beclin1 and mechanistic target of rapamycin (mTOR) proteins in epithelial ovarian cancer.

    Aberrant serum and tissue levels of Beclin1 and mechanistic target of rapamycin (mTOR) proteins in epithelial ovarian cancer.
    Lu H, Hu H, Yang Z, Li S., Free PMC Article

    05/3/2023
    GAPR-1 Interferes with Condensate Formation of Beclin 1 in Saccharomyces cerevisiae.

    GAPR-1 Interferes with Condensate Formation of Beclin 1 in Saccharomyces cerevisiae.
    Sirati N, Shen Z, Olrichs NK, Popova B, Verhoek IC, Lagerwaard IM, Braus GH, Kaloyanova DV, Helms JB.

    03/1/2023
    Superenhancers activate the autophagy-related genes Beclin1 and LC3B to drive metastasis and drug resistance in osteosarcoma.

    Superenhancers activate the autophagy-related genes Beclin1 and LC3B to drive metastasis and drug resistance in osteosarcoma.
    Wang H, Liu Z, Wang J, Hu F, Zhou Q, Wei L, Bao Q, Wang J, Liang J, Liu Z, Zhang W.

    01/21/2023
    Roles of Beclin1 protein expression in cervical cancer: a meta-analysis and bioinformatics analysis.

    Roles of Beclin1 protein expression in cervical cancer: a meta-analysis and bioinformatics analysis.
    Ma GY, Shi S, Ma HY, Zhang ZG.

    01/14/2023
    [Expression and significance of microtubule associated protein 1 light chain 3B, p62 and Beclin1 in lesion tissues of oral lichen planus patients].

    [Expression and significance of microtubule associated protein 1 light chain 3B, p62 and Beclin1 in lesion tissues of oral lichen planus patients].
    Shen MX, Hu WY, Cai Y.

    12/24/2022
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