| The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4. | The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4.
Yu S, Sun Z, Ju T, Liu Y, Mei Z, Wang C, Qu Z, Li N, Wu F, Liu K, Lu M, Huang M, Pang X, Jia Y, Li Y, Zhang Y, Dou S, Jiang J, Dong X, Huang C, Li W, Zhang Y, Yuan Y, Yang B, Du W., Free PMC Article | 09/16/2024 |
| EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis. | EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis.
Wang R, Lv C, Li D, Song Y, Yan Z. | 08/21/2024 |
| Investigation of the effect of SRSF9 overexpression on HIV-1 production. | Investigation of the effect of SRSF9 overexpression on HIV-1 production.
Kim GN, Yu KL, Kim HI, You JC., Free PMC Article | 12/31/2022 |
| High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis. | High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.
Zhang G, Liu B, Shang H, Wu G, Wu D, Wang L, Li S, Wang Z, Wang S, Yuan J., Free PMC Article | 08/27/2022 |
| SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner. | SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner.
Wang X, Lu X, Wang P, Chen Q, Xiong L, Tang M, Hong C, Lin X, Shi K, Liang L, Lin J., Free PMC Article | 05/14/2022 |
| SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon. | SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon.
Ha J, Jang H, Choi N, Oh J, Min C, Pradella D, Jung DW, Williams DR, Park D, Ghigna C, Zheng X, Shen H., Free PMC Article | 10/23/2021 |
| AMP-activated protein kinase regulates beta-catenin protein synthesis by phosphorylating serine/arginine-rich splicing factor 9. | AMP-activated protein kinase regulates β-catenin protein synthesis by phosphorylating serine/arginine-rich splicing factor 9.
Matsumoto E, Matsumoto Y, Inoue J, Yamamoto Y, Suzuki T. | 04/24/2021 |
| High SRSF9 expression is associated with cervical cancer. | microRNA-802 inhibits cell proliferation and induces apoptosis in human cervical cancer by targeting serine/arginine-rich splicing factor 9.
Zhang Q, Lv R, Guo W, Li X. | 08/15/2020 |
| LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation. | LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation.
Ninomiya K, Adachi S, Natsume T, Iwakiri J, Terai G, Asai K, Hirose T., Free PMC Article | 08/13/2020 |
| Results identified SRSF9 protein as one of the factors involved in modulating the splicing of the DDC mutated (c.714+4A>T) transcript. | Antisense oligonucleotides modulate dopa decarboxylase function in aromatic l-amino acid decarboxylase deficiency.
Tsai CR, Lee HF, Chi CS, Yang MT, Hsu CC. | 10/12/2019 |
| The splicing factor SRSF9 is a key factor that serves to restrict the editing of numerous protein-coding and non-coding sites to the brain. The results highlight the importance of SRSF9 as an editing regulator and suggest potential roles for other splicing factors. | SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates.
Shanmugam R, Zhang F, Srinivasan H, Charles Richard JL, Liu KI, Zhang X, Woo CWA, Chua ZHM, Buschdorf JP, Meaney MJ, Tan MH., Free PMC Article | 06/29/2019 |
| Dehydroepiandrosterone (DHEA) and cortisol modulate SRSF9 and SRSF3 in a different way and data suggest that the anti-glucocorticoid effect of DHEA, among other mechanisms, is also exerted by modulating the expression of proteins involved in the splicing of the GR pre-mRNA. | Role of spliceosome proteins in the regulation of glucocorticoid receptor isoforms by cortisol and dehydroepiandrosterone.
Buoso E, Galasso M, Ronfani M, Serafini MM, Lanni C, Corsini E, Racchi M. | 01/6/2018 |
| Report no correlation between expression of glucocorticoid receptor isoforms and SRp30c. | Expression of glucocorticoid receptor isoforms and associations with serine/arginine-rich protein 30c and 40 in patients with systemic lupus erythematosus.
Guan YC, Jiang L, Ma LL, Sun XN, Yu DD, Liu J, Qu DX, Fang MY. | 05/30/2015 |
| Overexpression of SRSF9 and SRSF1 promote beta-catenin accumulation via the recruitment of beta-catenin mRNA and by enhancing its translation in an mTOR-dependent manner. | SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis.
Fu Y, Huang B, Shi Z, Han J, Wang Y, Huangfu J, Wu W., Free PMC Article | 11/16/2013 |
| Relative levels of SRp20, SRp30c, and SRp40 in TM cells control differential expression of the two alternatively spliced isoforms of the GR and thereby regulate GC responsiveness. | Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells.
Jain A, Wordinger RJ, Yorio T, Clark AF., Free PMC Article | 04/28/2012 |
| these data indicated that tumor suppressive miR-1 induces apoptosis through direct inhibition of SRSF9 in bladder cancer. | Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer.
Yoshino H, Enokida H, Chiyomaru T, Tatarano S, Hidaka H, Yamasaki T, Gotannda T, Tachiwada T, Nohata N, Yamane T, Seki N, Nakagawa M. | 03/24/2012 |
| These results suggest that SRp30c can activate human papillomavirus type 16 L1 mRNA expression via a bimodal mechanism: directly by stimulating splicing to late splice sites and indirectly by inhibiting competing early splice sites. | Serine/arginine-rich protein 30c activates human papillomavirus type 16 L1 mRNA expression via a bimodal mechanism.
Somberg M, Li X, Johansson C, Orru B, Chang R, Rush M, Fay J, Ryan F, Schwartz S. | 11/12/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders.
Fingert JH, Alward WL, Wang K, Yorio T, Clark AF., Free PMC Article | 06/30/2010 |
| findings indicate the importance of arginine methylation for the subnuclear localization of SFRS9. | Arginine methylation analysis of the splicing-associated SR protein SFRS9/SRP30C.
Bressan GC, Moraes EC, Manfiolli AO, Kuniyoshi TM, Passos DO, Gomes MD, Kobarg J., Free PMC Article | 01/21/2010 |
| SRp30c stimulates splicing to the downstream 5' splice site of Bcl-x(L), thereby attenuating the repressive effect of upstream U1 snRNP binding sit | Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x.
Cloutier P, Toutant J, Shkreta L, Goekjian S, Revil T, Chabot B. | 01/21/2010 |
| Results suggest that bombesin-induced expression of SRp30c affects gllucorticoid receptor (GR) pre-mRNA splicing, leading to increased GR beta expression and contributing to glucocorticoid resistance in PC cells. | Bombesin attenuates pre-mRNA splicing of glucocorticoid receptor by regulating the expression of serine-arginine protein p30c (SRp30c) in prostate cancer cells.
Zhu J, Gong JY, Goodman OB Jr, Cartegni L, Nanus DM, Shen R., Free PMC Article | 01/21/2010 |
| Study shows that PTB can function as an anti-repressor molecule to counteract the splicing inhibitory activity of SRp30c. | hnRNP I/PTB can antagonize the splicing repressor activity of SRp30c.
Paradis C, Cloutier P, Shkreta L, Toutant J, Klarskov K, Chabot B., Free PMC Article | 01/21/2010 |
| Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils. | Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils.
Xu Q, Leung DY, Kisich KO. | 01/21/2010 |
| SRp30c can function as a repressor of 3' splice site utilization and suggest that the SRp30c-CE9 interaction may contribute to the control of hnRNP A1 alternative splicing. | SRp30c is a repressor of 3' splice site utilization.
Simard MJ, Chabot B., Free PMC Article | 01/21/2010 |
| SRp30c protein is an interacting protein of YB-1 | Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection.
Raffetseder U, Frye B, Rauen T, Jürchott K, Royer HD, Jansen PL, Mertens PR. | 01/21/2010 |