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    CBS cystathionine beta-synthase [ Homo sapiens (human) ]

    Gene ID: 875, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cystathionine-beta-synthase expression correlates with tumour progression and adverse prognosis in patients with colon cancer.

    Cystathionine-β-synthase expression correlates with tumour progression and adverse prognosis in patients with colon cancer.
    Hu XJ, Sun Y, Liu GJ, Zhang J, Zhang LX, Peng YH., Free PMC Article

    10/3/2024
    Cellular turnover and degradation of the most common missense cystathionine beta-synthase variants causing homocystinuria.

    Cellular turnover and degradation of the most common missense cystathionine beta-synthase variants causing homocystinuria.
    Mijatovic E, Ascenção K, Szabo C, Majtan T., Free PMC Article

    08/23/2024
    Biochemical and structural impact of two novel missense mutations in cystathionine beta-synthase gene associated with homocystinuria.

    Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria.
    Al-Sadeq DW, Conter C, Thanassoulas A, Al-Dewik N, Safieh-Garabedian B, Martínez-Cruz LA, Nasrallah GK, Astegno A, Nomikos M.

    05/7/2024
    Architecture and regulation of filamentous human cystathionine beta-synthase.

    Architecture and regulation of filamentous human cystathionine beta-synthase.
    McCorvie TJ, Adamoski D, Machado RAC, Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C, Baslé A, Ambrosio ALB, Dias SMG, Yue WW., Free PMC Article

    04/12/2024
    Association between CBS gene T833C, G919A and 844ins68 polymorphisms in the 8th exon region and coronary artery disease: a meta-analysis.

    Association between CBS gene T833C, G919A and 844ins68 polymorphisms in the 8th exon region and coronary artery disease: a meta-analysis.
    Zhu Z, Geng Y, Ma L, Yao K, Chang R, Ma Y, Li J.

    03/19/2024
    [Exploration of cystathionine beta-synthase and cystathionine gamma-lyase gene expression poor prognostic predictive value with the application of bioinformatics data mining in liver cancer].

    [Exploration of cystathionine β-synthase and cystathionine γ-lyase gene expression poor prognostic predictive value with the application of bioinformatics data mining in liver cancer].
    Liu ZJ, Ma YN.

    01/31/2024
    Disease-causing cystathionine beta-synthase linker mutations impair allosteric regulation.

    Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation.
    Roman JV, Mascarenhas R, Ceric K, Ballou DP, Banerjee R., Free PMC Article

    01/29/2024
    The Role of Cystathionine-beta-Synthase, H2S, and miRNA-377 in Hypoxic-Ischemic Encephalopathy: Insights from Human and Animal Studies.

    The Role of Cystathionine-β-Synthase, H(2)S, and miRNA-377 in Hypoxic-Ischemic Encephalopathy: Insights from Human and Animal Studies.
    Liu CY, Al-Ward H, Liu N, Mekontso FN, Chen W, Gao W, Zhang C, Murshed A, Yu ZR, Fan O, Sun YE, Xu H.

    01/5/2024
    ERalpha/ERbeta-directed CBS transcription mediates E2beta-stimulated hUAEC H2S production.

    ERα/ERβ-directed CBS transcription mediates E2β-stimulated hUAEC H2S production.
    Bai J, Lechuga TJ, Makhoul J, Yan H, Major C, Hameed A, Chen DB., Free PMC Article

    02/11/2023
    Understanding the role of R266K mutation in cystathionine beta-synthase (CBS) enzyme: an in silico study.

    Understanding the role of R266K mutation in cystathionine β-synthase (CBS) enzyme: an in silico study.
    Bhatt A, Ali ME.

    01/7/2023
    Congenital cataract: An ocular manifestation of classical homocystinuria.

    Congenital cataract: An ocular manifestation of classical homocystinuria.
    Saba N, Irshad S., Free PMC Article

    03/19/2022
    Inhibition of cystathionine beta-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia.

    Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia.
    Wang D, Yang H, Zhang Y, Hu R, Hu D, Wang Q, Liu Y, Liu M, Meng Z, Zhou W, Song W., Free PMC Article

    03/5/2022
    Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.

    Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.
    Padmanabhan N, Kyon HK, Boot A, Lim K, Srivastava S, Chen S, Wu Z, Lee HO, Mukundan VT, Chan C, Chan YK, Xuewen O, Pitt JJ, Isa ZFA, Xing M, Lee MH, Tan ALK, Ting SHW, Luftig MA, Kappei D, Kruger WD, Bian J, Ho YS, Teh M, Rozen SG, Tan P., Free PMC Article

    01/22/2022
    Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation.

    Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation.
    Erdélyi K, Ditrói T, Johansson HJ, Czikora Á, Balog N, Silwal-Pandit L, Ida T, Olasz J, Hajdú D, Mátrai Z, Csuka O, Uchida K, Tóvári J, Engebraten O, Akaike T, Børresen Dale AL, Kásler M, Lehtiö J, Nagy P., Free PMC Article

    12/18/2021
    A comprehensive association analysis between homocysteine metabolic pathway gene methylation and ischemic stroke in a Chinese hypertensive population.

    A comprehensive association analysis between homocysteine metabolic pathway gene methylation and ischemic stroke in a Chinese hypertensive population.
    Li B, Li Y, Xu S, Chen H, Dai S, Peng X, Wang L, Liang Y, Li C, Tang B, Zhu L, Zhang T, Lv C, Wang C, Han L., Free PMC Article

    11/6/2021
    Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.

    Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
    Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP.

    08/14/2021
    Liver transplant as a curative treatment in a pediatric patient with classic homocystinuria: A case report.

    Liver transplant as a curative treatment in a pediatric patient with classic homocystinuria: A case report.
    Kerkvliet SP, Rheault MN, Berry SA.

    08/7/2021
    CBS gene polymorphism and promoter methylation-mediating effects on the efficacy of folate therapy in patients with hyperhomocysteinemia.

    CBS gene polymorphism and promoter methylation-mediating effects on the efficacy of folate therapy in patients with hyperhomocysteinemia.
    Zhao Q, Zhang C, Li D, Huang X, Ren B, Yue L, Du B, Godfrey O, Zhang W.

    07/17/2021
    Association of maternal dietary intakes and CBS gene polymorphisms with congenital heart disease in offspring.

    Association of maternal dietary intakes and CBS gene polymorphisms with congenital heart disease in offspring.
    Li Y, Diao J, Li J, Luo L, Zhao L, Zhang S, Wang T, Chen L, Yang T, Chen L, Zhu P, Qin J.

    06/5/2021
    The values of AHCY and CBS promoter methylation on the diagnosis of cerebral infarction in Chinese Han population.

    The values of AHCY and CBS promoter methylation on the diagnosis of cerebral infarction in Chinese Han population.
    Li X, Bu S, Pan RR, Zhou C, Qu K, Ying X, Zhong J, Xiao J, Yuan Q, Zhang S, Tipton L, Wang Y, Deng Y, Duan S., Free PMC Article

    05/15/2021
    Cysteine becomes conditionally essential during hypobaric hypoxia and regulates adaptive neuro-physiological responses through CBS/H2S pathway.

    Cysteine becomes conditionally essential during hypobaric hypoxia and regulates adaptive neuro-physiological responses through CBS/H(2)S pathway.
    Mishra S, Kumar G, Chhabra A, Sethy NK, Jain N, Meena RN, Tulsawani R, Prasad DN, Kumar B, Sharma M.

    01/9/2021
    Cystathionine beta-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs(-/-) mice and thrombosis-prone CBS(-/-) humans.

    Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs(-/-) mice and thrombosis-prone CBS(-/-) humans.
    Sikora M, Lewandowska I, Marczak Ł, Bretes E, Jakubowski H., Free PMC Article

    12/5/2020
    Clinical Significance of CBS and CCL21 in Gallbladder Adenocarcinomas and Squamous Cell/Adenosquamous Carcinomas.

    Clinical Significance of CBS and CCL21 in Gallbladder Adenocarcinomas and Squamous Cell/Adenosquamous Carcinomas.
    Li D, Yang Z, Liu Z, Zou Q, Yuan Y.

    11/28/2020
    Association between cystathionine beta-synthase c.844ins68 polymorphism and risk of non-syndromic cleft lip/palate: A meta-analysis of family-based and case-control studies.

    Association between cystathionine beta-synthase c.844ins68 polymorphism and risk of non-syndromic cleft lip/palate: A meta-analysis of family-based and case-control studies.
    Imani MM, Safaei M, Sadeghi M.

    10/31/2020
    Natural history, with clinical, biochemical, and molecular characterization of classical homocystinuria in the Qatari population.

    Natural history, with clinical, biochemical, and molecular characterization of classical homocystinuria in the Qatari population.
    Al-Dewik N, Ali A, Mahmoud Y, Shahbeck N, Ali R, Mahmoud L, Al-Mureikhi M, Al-Mesaifri F, Musa S, El-Akouri K, Almulla M, Al Saadi R, Nasrallah GK, Samara M, Abdoh G, Rifai HA, Häberle J, Thöny B, Kruger W, Blom HJ, Ben-Omran T.

    09/19/2020
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