| Death receptor 5 promotes tumor progression in gastric cancer. | Death receptor 5 promotes tumor progression in gastric cancer.
Chen J, Li L, Huangfu L, Du H, Ji X, Xing X, Ji J., Free PMC Article | 12/16/2023 |
| TRAIL or TRAIL-R2 as a Predictive Biomarker for Mortality or Cardiovascular Events: A Systematic Review and Meta-analysis. | TRAIL or TRAIL-R2 as a Predictive Biomarker for Mortality or Cardiovascular Events: A Systematic Review and Meta-analysis.
Kuang N, Shu B, Yang F, Li S, Zhang M. | 05/23/2023 |
| TNFRSF10B is involved in motor dysfunction in Parkinson's disease by regulating exosomal alpha-synuclein secretion from microglia. | TNFRSF10B is involved in motor dysfunction in Parkinson's disease by regulating exosomal α-synuclein secretion from microglia.
Dai M, Yan L, Yu H, Chen C, Xie Y. | 04/21/2023 |
| Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5. | Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5.
Woo SM, Kim S, Seo SU, Kim S, Park JW, Kim G, Choi YR, Hur K, Kwon TK., Free PMC Article | 10/15/2022 |
| Elevated soluble death receptor 5 can predict poor prognosis in patients with acute respiratory distress syndrome. | Elevated soluble death receptor 5 can predict poor prognosis in patients with acute respiratory distress syndrome.
Qin J, Wang H, Lyu Z, Liao Y, Zeng N, Wang K, Zhou Y, Zeng Z, Liao Z, Cao Y, He J, Wang T, Wen F. | 09/10/2022 |
| Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer. | Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer.
Mora-Molina R, López-Rivas A., Free PMC Article | 09/3/2022 |
| Induction of DR5-Dependent Apoptosis by PGA2 through ATF4-CHOP Pathway. | Induction of DR5-Dependent Apoptosis by PGA(2) through ATF4-CHOP Pathway.
Park KM, Park JY, Pyo J, Lee SY, Kim HS., Free PMC Article | 07/2/2022 |
| TRAIL-receptor 2-a novel negative regulator of p53. | TRAIL-receptor 2-a novel negative regulator of p53.
Willms A, Schupp H, Poelker M, Adawy A, Debus JF, Hartwig T, Krichel T, Fritsch J, Singh S, Walczak H, von Karstedt S, Schäfer H, Trauzold A., Free PMC Article | 01/29/2022 |
| Enhanced extrinsic apoptosis of therapy-induced senescent cancer cells using a death receptor 5 (DR5) selective agonist. | Enhanced extrinsic apoptosis of therapy-induced senescent cancer cells using a death receptor 5 (DR5) selective agonist.
Soto-Gamez A, Wang Y, Zhou X, Seras L, Quax W, Demaria M. | 01/8/2022 |
| Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. | Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia.
Watanabe A, Miyake K, Akahane K, Goi K, Kagami K, Yagita H, Inukai T., Free PMC Article | 12/18/2021 |
| JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis. | JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.
Engler MJ, Mimura J, Yamazaki S, Itoh K., Free PMC Article | 12/4/2021 |
| Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. | Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas.
An Y, Jeon J, Sun L, Derakhshan A, Chen J, Carlson S, Cheng H, Silvin C, Yang X, Van Waes C, Chen Z., Free PMC Article | 10/16/2021 |
| Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. | Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2.
Jeong D, Kim HS, Kim HY, Kang MJ, Jung H, Oh Y, Kim D, Koh J, Cho SY, Jeon YK, Lee EB, Lee SH, Shin EC, Kim HM, Yi EC, Chung DH., Free PMC Article | 09/25/2021 |
| The SCF(Skp2) ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L). | The SCF(Skp2) ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L).
Roberts JZ, Holohan C, Sessler T, Fox J, Crawford N, Riley JS, Khawaja H, Majkut J, Evergren E, Humphreys LM, Ferris J, Higgins C, Espona-Fiedler M, Moynagh P, McDade SS, Longley DB., Free PMC Article | 09/25/2021 |
| Therapeutic targeting of FOS in mutant TERT cancers through removing TERT suppression of apoptosis via regulating survivin and TRAIL-R2. | Therapeutic targeting of FOS in mutant TERT cancers through removing TERT suppression of apoptosis via regulating survivin and TRAIL-R2.
Liu R, Tan J, Shen X, Jiang K, Wang C, Zhu G, Xing M., Free PMC Article | 09/11/2021 |
| Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress. | Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.
Lam M, Marsters SA, Ashkenazi A, Walter P., Free PMC Article | 08/28/2021 |
| Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy. | Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.
Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA., Free PMC Article | 06/12/2021 |
| Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells. | Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells.
Woo SM, Min KJ, Kwon TK., Free PMC Article | 03/6/2021 |
| Non-Thermal Plasma Couples Oxidative Stress to TRAIL Sensitization through DR5 Upregulation. | Non-Thermal Plasma Couples Oxidative Stress to TRAIL Sensitization through DR5 Upregulation.
Hwang SY, Nguyen NH, Kim TJ, Lee Y, Kang MA, Lee JS., Free PMC Article | 02/20/2021 |
| Luteolin enhances TRAIL sensitivity in non-small cell lung cancer cells through increasing DR5 expression and Drp1-mediated mitochondrial fission. | Luteolin enhances TRAIL sensitivity in non-small cell lung cancer cells through increasing DR5 expression and Drp1-mediated mitochondrial fission.
Wu B, Xiong J, Zhou Y, Wu Y, Song Y, Wang N, Chen L, Zhang J. | 11/21/2020 |
| TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation. | TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation.
Sullivan GP, O'Connor H, Henry CM, Davidovich P, Clancy DM, Albert ML, Cullen SP, Martin SJ. | 10/24/2020 |
| Curcumin-loaded nanostructured lipid carrier induced apoptosis in human HepG2 cells through activation of the DR5/caspase-mediated extrinsic apoptosis pathway. | Curcumin-loaded nanostructured lipid carrier induced apoptosis in human HepG2 cells through activation of the DR5/caspase-mediated extrinsic apoptosis pathway.
Wang F, Ye X, Zhai D, Dai W, Wu Y, Chen J, Chen W. | 10/3/2020 |
| TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. | TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, Warnatz K, Seidl M, Venhoff N, Thiel J, Smulski CR, Rizzi M., Free PMC Article | 10/3/2020 |
| The 9F7-F11 favored the extrinsic apoptosis pathway by inducing TRAIL-R2/DR5 upregulation and TRAIL expression that promoted the formation of death-inducing signaling complex (DISC) | ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
Le Clorennec C, Lazrek Y, Dubreuil O, Sampaio C, Larbouret C, Lanotte R, Poul MA, Barret JM, Prost JF, Pèlegrin A, Chardès T., Free PMC Article | 09/12/2020 |
| DR5 related autophagy can promote apoptosis in gliomas after irradiation. | DR5 related autophagy can promote apoptosis in gliomas after irradiation.
Zhang P, Wang H, Chen Y, Lodhi AF, Sun C, Sun F, Yan L, Deng Y, Ma H. | 09/5/2020 |