| PCAF promotes R-loop resolution via histone acetylation. | PCAF promotes R-loop resolution via histone acetylation.
Lee SY, Lee SH, Choi NH, Kim JY, Kweon JH, Miller KM, Kim JJ., Free PMC Article | 08/28/2024 |
| The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling. | The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling.
Ma W, Zhang J, Chen W, Liu N, Wu T., Free PMC Article | 05/1/2024 |
| Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. | Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYX, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW., Free PMC Article | 05/3/2023 |
| Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis. | Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis.
Ghasemi A, Farazmand A, Hassanzadeh V, Poursani S, Soltani S, Akhtari M, Akhlaghi M, Farhadi E, Jamshidi A, Mahmoudi M. | 01/28/2023 |
| Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation. | Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.
Qiu L, Liu X, Xia H, Xu C., Free PMC Article | 11/5/2022 |
| PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway. | PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway.
Kong C, Wang D, Wang F, Lv Y, Zhou W, Ye P, Gu Y, Jiang X, Zhu L, Ge Z, Chao Y, Chen S., Free PMC Article | 10/29/2022 |
| N4BP3 promotes angiogenesis in hepatocellular carcinoma by binding with KAT2B. | N4BP3 promotes angiogenesis in hepatocellular carcinoma by binding with KAT2B.
Han H, Zhu W, Lin T, Liu C, Zhai H., Free PMC Article | 10/15/2022 |
| Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts. | Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts.
Krošel M, Gabathuler M, Maciukiewicz M, Moser L, Lee GI, Marks M, Tomšič M, Distler O, Ospelt C, Klein K. | 02/26/2022 |
| Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity. | Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity.
Hatakeyama D, Shoji M, Ogata S, Masuda T, Nakano M, Komatsu T, Saitoh A, Makiyama K, Tsuneishi H, Miyatake A, Takahira M, Nishikawa E, Ohkubo A, Noda T, Kawaoka Y, Ohtsuki S, Kuzuhara T. | 02/26/2022 |
| Differential Expression Study of Lysine Crotonylation and Proteome for Chronic Obstructive Pulmonary Disease Combined with Type II Respiratory Failure. | Differential Expression Study of Lysine Crotonylation and Proteome for Chronic Obstructive Pulmonary Disease Combined with Type II Respiratory Failure.
Gan Q, Tang D, Yan Q, Chen J, Xu Y, Xue W, Xiao L, Zheng F, Xu H, Fu Y, Dai Y., Free PMC Article | 12/25/2021 |
| Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition. | Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition.
Hsu E, Zemke NR, Berk AJ., Free PMC Article | 12/11/2021 |
| Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma. | Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
Li L, Zhang J, Cao S., Free PMC Article | 11/13/2021 |
| P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation. | P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation.
Lim Y, Jeong A, Kwon DH, Lee YU, Kim YK, Ahn Y, Kook T, Park WJ, Kook H., Free PMC Article | 10/23/2021 |
| In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5. | In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5.
Hatakeyama D, Masuda T, Miki R, Ohtsuki S, Kuzuhara T., Free PMC Article | 05/22/2021 |
| Histone acetyltransferase p300 mediates the upregulation of CTEN induced by the activation of EGFR signaling in cancer cells. | Histone acetyltransferase p300 mediates the upregulation of CTEN induced by the activation of EGFR signaling in cancer cells.
Chang CC, Liu YC, Lin CH, Liao YC. | 04/17/2021 |
| Identification of epigenetic factor KAT2B gene variants for possible roles in congenital heart diseases. | Identification of epigenetic factor KAT2B gene variants for possible roles in congenital heart diseases.
Hou YS, Wang JZ, Shi S, Han Y, Zhang Y, Zhi JX, Xu C, Li FF, Wang GY, Liu SL., Free PMC Article | 04/3/2021 |
| PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation. | PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation.
Santi S, Cenni V, Capanni C, Lattanzi G, Mattioli E., Free PMC Article | 03/6/2021 |
| SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle. | SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle.
Lu YF, Xu XP, Lu XP, Zhu Q, Liu G, Bao YT, Wen H, Li YL, Gu W, Zhu WG., Free PMC Article | 11/28/2020 |
| PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. | PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
Kim JJ, Lee SY, Choi JH, Woo HG, Xhemalce B, Miller KM., Free PMC Article | 10/31/2020 |
| The Ras-ERK1/2 signaling pathway regulates H3K9ac through PCAF to promote the development of pancreatic cancer. | The Ras-ERK1/2 signaling pathway regulates H3K9ac through PCAF to promote the development of pancreatic cancer.
Li YH, Li YX, Li M, Song SW, Ge Y, Jin JY, Li XY, Tan XD, Ye J. | 09/5/2020 |
| PCAF regulated H3 Serine 28 phosphorylation and their axis promotes autophagy in osteosarcoma cancer. | PCAF regulates H3 phosphorylation and promotes autophagy in osteosarcoma cells.
Kong D, Ying B, Zhang J, Ying H. | 02/8/2020 |
| Our data suggest that PCAF-mediated p53 acetylation is an essential regulatory mechanism for increasing the susceptibility of colorectal cancer (CRC) to 5-FU. | Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil.
Liu T, Wang X, Hu W, Fang Z, Jin Y, Fang X, Miao QR., Free PMC Article | 11/30/2019 |
| a pro-apoptotic mechanism centered on the intrinsic (mitochondrial) pathway and regulated by PCAF/ADA3 can influence the progression from premalignant to malignant change, and thus act as a tumor suppression mechanism in gastric cancer. | Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.
Brasacchio D, Busuttil RA, Noori T, Johnstone RW, Boussioutas A, Trapani JA., Free PMC Article | 11/9/2019 |
| study revealed significant associations of two variants rs6598860 and rs4589135 in ARID1A with overweight/obesity. We also identified association of rs3804562 in KAT2B gene with body mass index | Common variants of ARID1A and KAT2B are associated with obesity in Indian adolescents.
Giri AK, Parekatt V, Dwivedi OP, Banerjee P, Bandesh K, Prasad G, Tandon N, Bharadwaj D., Free PMC Article | 10/12/2019 |
| Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells. | Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells.
Aoyama T, Okamoto T, Fukiage K, Otsuka S, Furu M, Ito K, Jin Y, Ueda M, Nagayama S, Nakayama T, Nakamura T, Toguchida J., Free PMC Article | 04/22/2019 |