Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19. | Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19. Shi W, Chen M, Pan T, Chen M, Cheng Y, Hao Y, Chen S, Tang Y., Free PMC Article | 11/28/2023 |
FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns. | FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns. Ebersberger S, Hipp C, Mulorz MM, Buchbender A, Hubrich D, Kang HS, Martínez-Lumbreras S, Kristofori P, Sutandy FXR, Llacsahuanga Allcca L, Schönfeld J, Bakisoglu C, Busch A, Hänel H, Tretow K, Welzel M, Di Liddo A, Möckel MM, Zarnack K, Ebersberger I, Legewie S, Luck K, Sattler M, König J. | 08/7/2023 |
FUBP1 promotes the proliferation of lung squamous carcinoma cells and regulates tumor immunity through PD-L1. | FUBP1 promotes the proliferation of lung squamous carcinoma cells and regulates tumor immunity through PD-L1. Yu J, Peng W, Xue Y, Li Y, Yang L, Geng Y. | 10/1/2022 |
FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/beta-catenin signaling. | FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/β-catenin signaling. Yin H, Gao T, Xie J, Huang Z, Zhang X, Yang F, Qi W, Yang Z, Zhou T, Gao G, Yang X., Free PMC Article | 07/16/2022 |
Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc. | Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc. Wang S, Wang Y, Li S, Nian S, Xu W, Liang F., Free PMC Article | 06/11/2022 |
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC. | The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC. Wang X, Xing L, Yang R, Chen H, Wang M, Jiang R, Zhang L, Chen J., Free PMC Article | 01/15/2022 |
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer. | TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer. Yang B, Chen J, Teng Y., Free PMC Article | 12/4/2021 |
LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC. | LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC. Qian X, Yang J, Qiu Q, Li X, Jiang C, Li J, Dong L, Ying K, Lu B, Chen E, Liu P, Lu Y., Free PMC Article | 11/6/2021 |
FUBP1 mediates the growth and metastasis through TGFbeta/Smad signaling in pancreatic adenocarcinoma. | FUBP1 mediates the growth and metastasis through TGFβ/Smad signaling in pancreatic adenocarcinoma. Zhang Y, Chen J, Zhou N, Lu Y, Lu J, Xing X, Chen H, Zhang X., Free PMC Article | 07/17/2021 |
Long non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p. | Long non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p. Zhang XX, Chen H, Li HY, Chen R, He L, Yang JL, Xiao LL, Chen JL., Free PMC Article | 06/19/2021 |
Differentially Expressed Long Noncoding RNAs Involved in FUBP1 Promoting Hepatocellular Carcinoma Cells Proliferation. | Differentially Expressed Long Noncoding RNAs Involved in FUBP1 Promoting Hepatocellular Carcinoma Cells Proliferation. Li X, Yu H, Xu F, Wu Y, Sheng J., Free PMC Article | 05/29/2021 |
High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity. | High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity. Liu W, Xiong X, Chen W, Li X, Hua X, Liu Z, Zhang Z., Free PMC Article | 05/8/2021 |
NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis. | NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis. Han T, Wu Y, Hu X, Chen Y, Jia W, He Q, Bian Y, Wang M, Guo X, Kang J, Wan X., Free PMC Article | 03/20/2021 |
Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival. | Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival. Kang M, Kim HJ, Kim TJ, Byun JS, Lee JH, Lee DH, Kim W, Kim DY., Free PMC Article | 03/6/2021 |
Overexpression of FUBP1 is associated with human cervical carcinoma development and prognosis. | Overexpression of FUBP1 is associated with human cervical carcinoma development and prognosis. Ma C, Huang Z, Wu Z, Di C, Lin X, Huang M, Hong H, Yin H. | 02/27/2021 |
Far upstream element-binding protein 1 facilitates hepatocellular carcinoma invasion and metastasis. | Far upstream element-binding protein 1 facilitates hepatocellular carcinoma invasion and metastasis. Fu PY, Hu B, Ma XL, Tang WG, Yang ZF, Sun HX, Yu MC, Huang A, Hu JW, Zhou CH, Fan J, Xu Y, Zhou J. | 02/6/2021 |
Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. | Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. Elman JS, Ni TK, Mengwasser KE, Jin D, Wronski A, Elledge SJ, Kuperwasser C., Free PMC Article | 10/24/2020 |
elevated FUBP1 promotes NB glycolysis and growth by targeting HIF1alpha rather than N-Myc, suggesting that FUBP1 is a novel and powerful oncogene in the development of NB independent of N-Myc and may have potential in the diagnosis and treatment of NB. | FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma. Jiang P, Huang M, Qi W, Wang F, Yang T, Gao T, Luo C, Deng J, Yang Z, Zhou T, Zou Y, Gao G, Yang X., Free PMC Article | 02/15/2020 |
Data indicate a T-cell acute lymphocytic leukaemia 1 (TAL1) /FUSE binding protein 1 (FUBP1) transcriptional relationship, whose physiological function in haematopoiesis is connected to proper erythropoiesis. | FUSE binding protein 1 (FUBP1) expression is upregulated by T-cell acute lymphocytic leukemia protein 1 (TAL1) and required for efficient erythroid differentiation. Steiner M, Schneider L, Yillah J, Gerlach K, Kuvardina ON, Meyer A, Maring A, Bonig H, Seifried E, Zörnig M, Lausen J., Free PMC Article | 11/23/2019 |
High FUBP1 expression is associated with myeloid leukemia. | The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia. Hoang VT, Verma D, Godavarthy PS, Llavona P, Steiner M, Gerlach K, Michels BE, Bohnenberger H, Wachter A, Oellerich T, Müller-Kuller U, Weissenberger E, Voutsinas JM, Oehler VG, Farin HF, Zörnig M, Krause DS. | 11/16/2019 |
The results reveal a new mechanism of action of RUNX1 that implicates FUBP1, as a facilitator, to trigger transcriptional regulation of c-KIT and to regulate cell proliferation in precursor B-cell lymphoblastic leukemia. | Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB, Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB., Free PMC Articles: PMC6265458, PMC6265458 | 06/22/2019 |
FUBP1 regulates the oncogene KIT by binding to its enhancer, and its promoter, and by interacting with RUNX1. | Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB, Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB., Free PMC Articles: PMC6265458, PMC6265458 | 05/30/2019 |
FUBP1 promotes tumor cell proliferation and migration and regulates the cancer cell immunity by increasing the PD-L1 expression mediated by Myc in pancreatic cancer cells. | Far upstream element-binding protein 1 is up-regulated in pancreatic cancer and modulates immune response by increasing programmed death ligand 1. Fan P, Ma J, Jin X. | 05/18/2019 |
High FUBP1 expression is associated with low Chemosensitivity to Adriamycin in Gastric Cancer. | MiR-16-1 Targeted Silences Far Upstream Element Binding Protein 1 to Advance the Chemosensitivity to Adriamycin in Gastric Cancer. Zhao D, Zhang Y, Song L. | 10/27/2018 |
Low FUBP1 expression is associated with adenovirus infection. | Adenovirus 5 E1A-Mediated Suppression of p53 via FUBP1. Frost JR, Mendez M, Soriano AM, Crisostomo L, Olanubi O, Radko S, Pelka P., Free PMC Article | 07/28/2018 |