| MPZL1 Promotes Lung Adenocarcinoma Progression by Enhancing Tumor Proliferation, Invasion, Migration, and Suppressing Immune Function via Transforming Growth Factor-beta1. | MPZL1 Promotes Lung Adenocarcinoma Progression by Enhancing Tumor Proliferation, Invasion, Migration, and Suppressing Immune Function via Transforming Growth Factor-β1.
Wang A, Fan F, Zang C, Li C, Hong H, Wang Z, Gao Y, Chen L, Yu X, Zhou C, Zhao C. | 06/26/2023 |
| MPZL1 upregulation promotes tumor metastasis and correlates with unfavorable prognosis in non-small cell lung cancer. | MPZL1 upregulation promotes tumor metastasis and correlates with unfavorable prognosis in non-small cell lung cancer.
Feng J, Ouyang H, Wang J, Pan D, Sheng L, Xu C, Lin W, Hu D, Chang C, Jia D. | 12/3/2022 |
| LncRNA TNFRSF10A-AS1 promotes gastric cancer by directly binding to oncogenic MPZL1 and is associated with patient outcome. | LncRNA TNFRSF10A-AS1 promotes gastric cancer by directly binding to oncogenic MPZL1 and is associated with patient outcome.
Sun D, Gou H, Wang D, Li C, Li Y, Su H, Wang X, Zhang X, Yu J., Free PMC Article | 06/11/2022 |
| High MPZL1 expression is associated with proliferation and metastasis of ovarian cancer. | MPZL1 promotes tumor cell proliferation and migration via activation of Src kinase in ovarian cancer.
Chen D, Cao L, Wang X., Free PMC Article | 01/25/2020 |
| The present study showed that the expression and protein levels of MPZL1 were significantly higher in gallbladder carcinoma tissues, especially in patients diagnosed with advanced tumor stages. | MPZL1 is highly expressed in advanced gallbladder carcinoma and promotes the aggressive behavior of human gallbladder carcinoma GBC‑SD cells.
Liu X, Huang J, Liu L, Liu R., Free PMC Article | 01/18/2020 |
| Data indicate that myelin protein zero-like 1 (PZR) may promote the invasion and migration of colorectal cancer (CRC) cells through increasing the phosphorylation of focal adhesion kinase (FAK) and protooncogene SRC (Src). | PZR promotes metastasis of colorectal cancer through increasing FAK and Src phosphorylation.
Tan D, Zhang W, Tao Y, Galiya Y, Wang M. | 08/10/2019 |
| These data demonstrate that the formation of this MPZL1-PTPN11-GRB2 complex is triggered by the attachment of HER2+ breast cancer cells to fibronectin. | MPZL1 forms a signalling complex with GRB2 adaptor and PTPN11 phosphatase in HER2-positive breast cancer cells.
Beigbeder A, Chartier FJM, Bisson N., Free PMC Article | 06/29/2019 |
| dimerization of MPZL1 participates in control of its signal transmission in cell adhesion. | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1.
Yu T, Liang L, Zhao X, Yin Y. | 05/18/2019 |
| MPZL1 is a target gene within the 1q24.1-24.2 amplicon that plays a pivotal role in HCC cell migration and tumor metastasis, and a novel MPZL1/Src/cortactin signaling cascade. | Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma.
Jia D, Jing Y, Zhang Z, Liu L, Ding J, Zhao F, Ge C, Wang Q, Chen T, Yao M, Li J, Gu J, He X., Free PMC Article | 09/27/2014 |
| Clinico-electrophysiological features and MRI findings are described in leg musculature from three patients belonging to a CMT2J pedigree due to MPZ Thr124Met mutation. | Charcot–Marie–Tooth disease type 2J with MPZ Thr124Met mutation: clinico-electrophysiological and MRI study of a family.
Gallardo E, García A, Ramón C, Maraví E, Infante J, Gastón I, Alonso Á, Combarros O, De Jonghe P, Berciano J. | 01/21/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Phosphorylation and localization of PZR in cultured endothelial cells is reported. | Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells.
Kusano K, Thomas TN, Fujiwara K., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesFollow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.
Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW. MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese.
He G, Liu X, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L, He G, Liu X, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L. | 03/13/2008 |
| PZR is a major receptor of ConA and has an important role in cell signaling via c-Src. Considering the various biological activities of ConA, the study of PZR may have major therapeutic implications | Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling.
Zhao R, Guerrah A, Tang H, Zhao ZJ. | 01/21/2010 |
| Characterization of PZR1b, an alternative spliced isoform of PZR. | Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs.
Zhao R, Zhao ZJ. | 01/21/2010 |
| the MPZL1/PZR gene may be important in the predisposition to schizophrenia among Han Chinese | MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese.
He G, Liu X, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L, He G, Liu X, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L. | 01/21/2010 |